Results 81 to 90 of about 529,540 (301)

PTHrP treatment of colon cancer cells promotes tumor associated-angiogenesis by the effect of VEGF [PDF]

, 2019
We showed that Parathyroid Hormone-related Peptide (PTHrP) induces proliferation, migration, survival and chemoresistance via MAPKs and PI3K/AKT pathways in colorectal cancer (CRC) cells.
Calvo, Natalia Graciela, Carriere, Pedro Matias, Gentili, Claudia Rosana, Gigola, Graciela, Martín, María Julia   +4 more
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Patient Preferences for Anti-Vascular Endothelial Growth Factor Treatment for Wet Age-Related Macular Degeneration in Japan: A Discrete Choice Experiment

Patient Preference and Adherence, 2020
Takeshi Joko,1 Yoshimi Nagai,2 Ryusaburo Mori,3 Koji Tanaka,3 Yuji Oshima,4 Yusuke Hikichi,5 Tetsushi Komori,6 Joao Carrasco,7 Martine C Maculaitis,8 Oliver Will,8 Kathleen Beusterien,8 Kanji Takahashi2 1Department of Ophthalmology, Matsuyama Red Cross ...
Joko T, Nagai Y, Mori R, Tanaka K, Oshima Y, Hikichi Y, Komori T, Carrasco J, Maculaitis MC, Will O, Beusterien K, Takahashi K   +11 more
doaj  

Microvascular alterations in hypertension and vascular aging [PDF]

, 2017
Hypertension and aging are characterized by vascular remodelling and stiffness as well as endothelial dysfunction. Endothelial function declines with age, since aging is associated with senescence of the endothelium due to increased rate of apoptosis and
Battistoni, Allegra, Calvez, Valentin, Cesario, Vincenzo, Filippini, Antonio, Montefusco, G, Savoia, Carmine   +5 more
core   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

مروری بر درمان‌های دارويی ادم سيستوئيد ماکولای سودوفيکيک [PDF]

, 2012
زمينه و هدف : هدف اين مطالعه مروری بر درمان های دارويی ادم سيستوئيد ماکولای سودوفيکيک بود. روش کار : اين بررسی، مروری سيستماتيک بر روش های درمانی پذيرفته شده در ادم سيستوئيد ماکولای سودوفيکيک ( Pseudophakic Cystoid Macular Edema: PCME )است. پارامترهای
حتم خانی, شیما, صعودی, رضا, مدرس زاده, مهدی   +2 more
core  

Escaping Antiangiogenic Therapy: Strategies Employed by Cancer Cells [PDF]

, 2016
Indexación: Web of ScienceTumor angiogenesis is widely recognized as one of the hallmarks of cancer. Consequently, during the last decades the development and testing of commercial angiogenic inhibitors has been a central focus for both basic and ...
Carrasco-Avino, G, Corvalan, AH, Owen, GI, Pinto, MP, Sotomayor, P   +4 more
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Update on Anti-Vascular Endothelial Growth Factor Safety for Retinopathy of Prematurity

Asia-Pacific Journal of Ophthalmology, 2020
Retinopathy of prematurity (ROP) is a neovascular retinal disorder that occurs in infants born prematurely. Nowadays, ROP constitutes a leading cause of childhood blindness worldwide and for decades the standard of care has involved peripheral retinal ablation.
Ana Bety, Enríquez, Robert L, Avery, Caroline R, Baumal   +2 more
openaire   +2 more sources

High‐Resolution and Real‐Time In Situ Generation of Cellular Spheroids by Laser‐Assisted Bioprinting for Guided Microvascularization

Advanced Functional Materials, EarlyView.
Micro‐injection laser‐assisted bioprinting enables ultrafast and precise patterning of small endothelial cell spheroids by injecting a highly concentrated single‐cell suspension into GelMA/ColMA hydrogels. In co‐culture with fibroblasts, controlled pre‐vasculogenic network formation is obtained at microscale resolution.
Charles Handschin, Katharina Wulz, Clotilde Jugie, Marie‐Laure Stachowicz, Shane Fennell, Aurélien Mazet, Malou Lea, Nathalie Dusserre, Jean‐Christophe Fricain, Hugo Oliveira   +9 more
wiley   +1 more source