Antitumor activity of a novel anti-vascular endothelial growth factor receptor-1 monoclonal antibody that does not interfere with ligand binding [PDF]
, 2016 Vascular endothelial growth factor receptor-1 (VEGFR-1) is a tyrosine kinase transmembrane receptor that has also a soluble isoform containing most of the extracellular ligand binding domain (sVEGFR-1).
Atzori, MG +10 more
core +1 more source
Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells
FEBS Open Bio, EarlyView.Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi +7 more
wiley +1 more source
Офтальмохирургия, 2023 Relevance. Radiation retinopathy and maculopathy are the most common causes of visual impairment in patients with uveal melanoma treated with plaque radiotherapy.
E.P. Sudakova +2 more
doaj +1 more source
The Effects of Channa Striatus Extract Administration on Wound Healing Markers (il-6, Mmp-9 and Vegf) in Post Lower Segment Caesarean Section (lscs) Women [PDF]
, 2016 Channa Striatus (Haruan) digunakan secara meluas di Malaysia untuk menggalakkan penyembuhan luka. Sejak turun temurun, C.striatus telah dipercayai mempunyai sifat anti-radang, anti-oksida dan anti sakit untuk penyembuhan luka yang lebih baik ...
Zainan, Ahmad Ezam
core
Specialized mouse embryonic stem cells for studying vascular development. [PDF]
, 2014 Vascular progenitor cells are desirable in a variety of therapeutic strategies; however, the lineage commitment of endothelial and smooth muscle cell from a common progenitor is not well-understood.
Burns, Andrew B +5 more
core +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
OkulistykaAngioid streaks, a rare defect of Bruch’s membrane, are most typically characterized by an asymptomatic course. However, when complications such as submacular hemorrhage or a neovascular membrane develop, visual acuity may deteriorate markedly, requiring
Karolina Agnieszka Korycińska +2 more
doaj +1 more source
Anti–Vascular Endothelial Growth Factor Bevacizumab (Avastin) for Radiation Retinopathy [PDF]
Archives of Ophthalmology, 2007 To evaluate intravitreal bevacizumab for radiation retinopathy.After plaque radiation therapy, 6 patients developed radiation retinopathy (retinal edema, hemorrhages, microangiopathy, and neovascularization). Intravitreal bevacizumab (1.25 mg in 0.05 mL) was periodically injected (every 6-8 weeks).
Paul T, Finger, Kimberly, Chin
openaire +2 more sources
VEGF(164)-mediated inflammation is required for pathological, but not physiological, ischemia-induced retinal neovascularization [PDF]
, 2003 Hypoxia-induced VEGF governs both physiological retinal vascular development and pathological retinal neovascularization. In the current paper, the mechanisms of physiological and pathological neovascularization are compared and contrasted.
Adamis, AP +14 more
core +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source