pH-Sensitive Chitosan–Heparin Nanoparticles for Effective Delivery of Genetic Drugs into Epithelial Cells [PDF]
Chitosan has been extensively studied as a genetic drug delivery platform. However, its efficiency is limited by the strength of DNA and RNA binding.
Korzhikov-Vlakh, Viktor +7 more
core +1 more source
BackgroundVascular endothelial growth factor-A (VEGF) is one of the key regulators of tumor development, hence it is considered to be an important therapeutic target for cancer treatment. However, clinical trials have suggested that anti-VEGF monotherapy
Kiyoshi Masuda +7 more
doaj +1 more source
Bevacizumab radioimmunotherapy (RIT) with accelerated blood clearance using the avidin chase [PDF]
学位記番号 ...
RYAN, YUDISTIRO +1 more
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Kemajuan Visus Penderita Retinopati Diabetik yang Diterapi dengan Laser Fotokoagulasi dan atau Injeksi Intravitreal di Rumah Sakit Mohammad Hoesin Palembang [PDF]
Retinopati diabetes adalah kelainan retina yang ditemukan pada penderita diabetes melitus. Insiden retinopati diabetik mencapai 40-50% penderita diabetes dan prognosisnya yang kurang baik terutama bagi tajam penglihatan.
Amin, R. (Ramzi) +2 more
core +2 more sources
Anti-VEGF in a Marathon Runner’s Retinopathy Case
Central retinal vein occlusion (CRVO) is one of the most common retinal vascular disorders. Intense exercise associated CRVO have been described in otherwise healthy young patients. We describe a case of a young male ultramarathoner who presented with a CRVO, presumably associated with dehydration, making part of a marathon runner’s retinopathy ...
Alexander Kahjun Soon +2 more
openaire +4 more sources
EMP2 regulates angiogenesis in endometrial cancer cells through induction of VEGF. [PDF]
Understanding tumor-induced angiogenesis is a challenging problem with important consequences for the diagnosis and treatment of cancer. In this study, we define a novel function for epithelial membrane protein-2 (EMP2) in the control of angiogenesis ...
Braun, J +7 more
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NF2/merlin in hereditary neurofibromatosis 2 versus cancer: biologic mechanisms and clinical associations. [PDF]
Inactivating germline mutations in the tumor suppressor gene NF2 cause the hereditary syndrome neurofibromatosis 2, which is characterized by the development of neoplasms of the nervous system, most notably bilateral vestibular schwannoma.
Angelo, Laura S +2 more
core +3 more sources
Vascular endothelial growth factor (VEGF) plays a critical role in initiating a cascade of reactions important for the normal as well as abnormal angiogenesis.
Ashok K Dubey, N R Biswas, G K Das
doaj +1 more source
Integrated results from the COPERNICUS and GALILEO studies. [PDF]
OBJECTIVES: To report on the efficacy and safety of intravitreal aflibercept in patients with macular edema secondary to central retinal vein occlusion (CRVO) in an integrated analysis of COPERNICUS and GALILEO.
Ahlers, Christiane +13 more
core +3 more sources
Thromboembolic events in patients treated with anti-angiogenic drugs [PDF]
Induction of neo-angiogenesis is a fundamental step in many pathological conditions. The therapeutic value of inhibiting angiogenesis is an interesting area of research in oncology, with vascular endothelial growth factor (VEGF) being the most suitable ...
Ferroni, P +3 more
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