Results 201 to 210 of about 266,823 (339)

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source

Anatomical and Functional Outcomes of Anti-VEGF Therapy in Pachychoroid Neovasculopathy. [PDF]

Clin Ophthalmol
Sitnilska V, Pohl JM, Tang Y, Löw K, Lammert JQ, Krohne TU, Altay L.   +6 more
europepmc   +1 more source

If a patient experiences a single floater immediately after an intravitreal anti-VEGF injection, will it resolve over time? If yes, how long does it take?

Tripdatabase
openalex   +1 more source

Outer retinal tubulations response to anti-VEGF treatment [PDF]

, 2015
Mark Espina, Cheryl A. Arcinue, Feiyan Ma, Natalia Camacho, Giulio Barteselli, Nadia Mendoza, Napoleone Ferrara, William R. Freeman   +7 more
openalex   +1 more source

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

Advanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang, Xin Zhou, Min Liu, Meimei Huang, Peirong Chen, Xinying Li, Fangchao Xue, Wenyan Zhao, Di Liu, Lang Li, Yuangang Lu, Wen Zeng   +11 more
wiley   +1 more source

Anti‐VEGF Therapy in Breast and Lung Mouse Models of Cancers [PDF]

, 2010
Marina Di Domenico, C. Ricciardi, Alfredo Fusco, Pierantoni Giovanna Maria   +3 more
openalex   +1 more source

Anti-VEGF Monoclonal Antibody [PDF]

, 2020
openaire   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

Factors Involved in Anti-VEGF Treatment Decisions for Neovascular Age-Related Macular Degeneration: Insights from Real-World Clinical Practice

Clinical Ophthalmology
Glenn Yiu,1 Shilpa Gulati,2 Victoria Higgins,3 Emily Coak,3 Daniel Mascia,3 Eunice Kim,4 Galin Spicer,4 David Tabano4 1Department of Ophthalmology & Vision Science, University of California, Davis Health, Sacramento, CA, USA; 2New England Retina ...
Yiu G, Gulati S, Higgins V, Coak E, Mascia D, Kim E, Spicer G, Tabano D   +7 more
doaj  

Gene profiling of human VEGF signaling pathways in human endothelial and retinal pigment epithelial cells after anti VEGF treatment [PDF]

, 2014
Shani Golan, Michal Entin‐Meer, Yonathan Semo, Sofia Maysel-Auslender, Daphna Mezad-Koursh, Gad Keren, Anat Loewenstein, Adiel Barak   +7 more
openalex   +1 more source