Results 231 to 240 of about 266,823 (339)

Anti-VEGF Treatment for Bilateral Choroidal Neovascularization Secondary to Laser Pointer Injury in a Child: Case Report. [PDF]

Turk J Ophthalmol
Günay SE, Akça Bayar S, Gökgöz G, Yılmaz G.   +3 more
europepmc   +1 more source

Re: Israilevich et al.: Risk of endophthalmitis based on cumulative number of anti-VEGF intravitreal injections (Ophthalmology. 2024;131:667–673) [PDF]

Yohei Hashimoto
openalex   +1 more source

PTG‐Dependent Glycogen Metabolic Dysfunction Drives Impaired Adipose Browning: A Novel Mechanism Linking PM2.5 to Metabolic Disorders

Advanced Science, EarlyView.
This study provides the first evidence that PM2.5 impairs iWAT browning via PTG‐mediated glycogen metabolism disruption, which is initiated by ADRB3 inhibition and subsequently triggers VEGFB upregulation. It thereby delineates the ADRB3‐PTG‐VEGFB axis as central to PM2.5‐induced metabolic dysfunction and identifies adipose glycogen metabolism as a ...
Limin Wang, Renjie Hu, Yanxi Chai, Ping He, Sanduo Li, Lisha Zhao, Wenbin Zhao, Lu Zhang, Li Qin, Ran Li, Xiaoli Hou, Qinghua Sun, Cuiqing Liu   +12 more
wiley   +1 more source

DME-RWKV: An Interpretable Multimodal Deep Learning Framework for Predicting Anti-VEGF Response in Diabetic Macular Edema. [PDF]

Bioengineering (Basel)
Liu Y, Xu X, Zhang J, Wang H, Shen A, Song X, Xu X, Fu Y.   +7 more
europepmc   +1 more source

PBRM1 Deficiency Reshapes an Immune Suppressive Microenvironment Through Epigenetic Tuning of PBRM1‐KDM5C‐IL6 Axis in ccRCC

Advanced Science, EarlyView.
PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia, Hongru Wang, Yu Dong, Zitong Yang, Yiyang Zhou, Zhinan Xia, Qinchen Li, Liangliang Ren, Yichun Zheng, Junliang Yan, Dongmei Ma, Zhi Chen, Xingang Cui, Guixin Zhu, Cheng Zhang   +14 more
wiley   +1 more source

Novel anti-VEGF scFv antibodies with superior in vitro and in vivo activities. [PDF]

Sci Rep
Cakan-Akdogan G, Erez O, Ozer C, Onal E, Mert O, Gullu S, Arslan M, Avci ME, Inan M, Kalyoncu S.   +9 more
europepmc   +1 more source

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source

Analysis of OCT-Based Biomarkers and Recurrence in Eyes with Diabetic Macular Edema Following Anti-VEGF Therapy. [PDF]

Int J Gen Med
Zhu T, Wang Y, Hua Y, Zha X, Xu T.
europepmc   +1 more source

Immunomodulatory Hydrogel Coating with SeNPs and Lithium Silicate Synergistically Promotes Osseointegration and Prevents Infection on Titanium Implants

Advanced Science, EarlyView.
This study introduces a multifunctional hydrogel coating (Lap‐CMCSMA/GelMA@SeNPs) that scavenges ROS, modulates immune responses, and shows strong antibacterial activity. It effectively restores the peri‐implant microenvironment. The coating exhibits excellent biocompatibility and promotes osteogenic differentiation.
Su Jiang, Baisheng Cai, Cong Ye, Kefan Wu, Kuan Liu, Pengcheng Xu, Fan Liu, Yake Liu   +7 more
wiley   +1 more source

Future horizons in diabetic macular edema management: nanocarriers as a promising alternative to conventional anti-VEGF therapy. [PDF]

Ann Med Surg (Lond)
Ammer R, Khan MW, Hanan M, Talha M, Fatima M.   +4 more
europepmc   +1 more source