Results 211 to 220 of about 44,369 (290)

Thorough QT/QTc Clinical Study to Evaluate the Effect of Remdesivir on Cardiac Repolarization in Healthy Participants

open access: yesClinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT QT interval prolongation associated with drug administration is an important consideration in drug development. Patients with COVID‐19 are at increased risk for cardiac complications, and QT interval prolongation correlates with higher mortality.
Chi‐Chi Peng   +6 more
wiley   +1 more source

Advances in Electrocardiogram‐Based Non‐Invasive Blood Glucose Monitoring Technology

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4445-4463, June 2026.
ABSTRACT Blood glucose monitoring is fundamental to diabetes management, yet traditional invasive methods are limited by patient discomfort and infection risks. In recent years, electrocardiogram (ECG), a conventional tool for cardiovascular assessment, has gained attention as a prospective method for non‐invasive blood glucose monitoring.
Qi Zeng   +5 more
wiley   +1 more source

Anti‐cancer drugs targeting the NADH‐binding site of VDAC rewire channel electrophysiology and partially suppress cation selectivity

open access: yesThe FEBS Journal, Volume 293, Issue 12, Page 3663-3682, June 2026.
VA molecules alter VDAC1 gating by increasing anion flow and reducing cation permeability. In cancer cells, which rely on ER‐mitochondria Ca2+ transfer and overexpress VDAC1, this imbalance triggers bioenergetic stress, ROS buildup, and mitochondrial collapse, leading to cell death.
Stefano Conti‐Nibali   +6 more
wiley   +1 more source

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