Results 1 to 10 of about 19,342 (221)

Arrhythmogenic Risk Assessment Following Four-Week Pretreatment With Nicotine and Black Tea in Rat [PDF]

open access: yes, 2015
Background: There is the controversy concerning the main component of tobacco, which is responsible for its arrhythmogenesis. In addition, there is the lack of adequate information about the influence of combination of black tea and nicotine on heart ...
Ghasemipoor Afshar, Elham   +4 more
core   +1 more source

Propafenone HCl fast dissolving tablets containing subliming agent prepared by direct compression method

open access: yesSaudi Pharmaceutical Journal, 2017
Propafenone HCl (PPH), an antiarrhythmic drug, has a bitter taste, short half-life, delayed drug dissolution and side effects. Thus, the purpose of this work is to develop orally fast dissolving tablets (OFDTs) containing PPH to provide a rapid drug ...
Saleh Abd El Rasoul, Gamal A. Shazly
doaj   +1 more source

Dronedarone. [PDF]

open access: yes, 2009
Amiodarone is the most effective antiarrhythmic drug for maintaining sinus rhythm for patients with atrial fibrillation. Extra-cardiac side effects have been a limiting factor, especially during chronic use, and may offset its benefits.
Kowey, Peter R   +2 more
core   +1 more source

A review on dronedarone: Pharmacological, pharmacodynamic and pharmacokinetic profile

open access: yesJournal of Acute Disease, 2016
Dronedarone, a benzofuran containing chemical compound, is a derivative of amiodarone which is classified as a Class III antiarrhythmic agent. It is prescribed to the cardiovascular patients who have paroxysmal or persistent atrial fibrillation to lower ...
Farah Iram   +4 more
doaj   +1 more source

Cost effectiveness of the implantable cardioverter defibrillator: a preliminary analysis [PDF]

open access: yes, 1992
Background-An implantable cardioverter defibrillator (ICD) maybe effective in reducing the risk of sudden cardiac death. The high cost of ICD treatment, however, compared with alternatives raises the question of whether this new technology is an ...
Buxton, MJ, O'Brien, BJ, Rusby, RA
core  

On mechanism of antiarrhythmic action of some dimethylphenylacetamide derivatives [PDF]

open access: yes, 2018
The study aim was to identify essential elements of the antiarrhythmic action mechanism of tertiary and quaternary derivatives of Dimethylphenylacetamide.
Blinova, E. V.   +4 more
core   +2 more sources

Blockade by NIP-142, an Antiarrhythmic Agent, of Carbachol-Induced Atrial Action Potential Shortening and GIRK1/4 Channel

open access: yesJournal of Pharmacological Sciences, 2006
.: Mechanisms for the atria-specific action potential-prolonging action of NIP-142 ((3R*,4S*)-4-cyclopropylamino-3,4-dihydro-2,2-dimethyl-6-(4-methoxyphenylacetylamino)-7-nitro-2H-1-benzopyran-3-ol), a benzopyran compound that terminates experimental ...
Matsuda Tomoyuki   +10 more
doaj   +1 more source

Management of atrial fibrillation [PDF]

open access: yes, 1997
Atrial fibrillation is the most commonly encountered sustained arrhythmia. The spectrum of symptomatology and presentation are broad. The goals of treatment should include (1) identification of any underlying cause(s) and/or precipitating factor(s), (2 ...
Lau, CP, Tse, HF
core   +1 more source

The study of electrophysiological mechanisms of the action compounds LMG-124

open access: yesФармакокинетика и Фармакодинамика, 2017
In vitro experiments performed on the isolated rats hippocampal neurons, the antiarrhythmic activity electrophysiological mechanisms of the complex compound LMG-124 containing an antiarrhythmic agent of the class I by Vaughan Williams, Lappaconitine ...
I. B. Tsorin   +6 more
doaj  

Amiodarone-Induced Pulmonary Toxicity - A Frequently Missed Complication. [PDF]

open access: yes, 2016
IntroductionAmiodarone is often used in the suppression of tachyarrhythmias. One of the more serious adverse effects includes amiodarone pulmonary toxicity (APT).
Dang, Natasha   +4 more
core   +2 more sources

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