Results 91 to 100 of about 3,249,675 (219)

Cost effectiveness of the implantable cardioverter defibrillator: a preliminary analysis [PDF]

, 1992
Background-An implantable cardioverter defibrillator (ICD) maybe effective in reducing the risk of sudden cardiac death. The high cost of ICD treatment, however, compared with alternatives raises the question of whether this new technology is an ...
Buxton, MJ, O'Brien, BJ, Rusby, RA
core  

The study of electrophysiological mechanisms of the action compounds LMG-124

Фармакокинетика и Фармакодинамика, 2017
In vitro experiments performed on the isolated rats hippocampal neurons, the antiarrhythmic activity electrophysiological mechanisms of the complex compound LMG-124 containing an antiarrhythmic agent of the class I by Vaughan Williams, Lappaconitine ...
I. B. Tsorin, V. P. Zinchenko, I. Yu. Teplov, A. M. Kosenkov, Yu. I. Murinov, M. S. Yunusov, S. A. Kryzhanovskii   +6 more
doaj  

Case Report of Long QT Syndrome in a Patient With Syncope

The Kaohsiung Journal of Medical Sciences, EarlyView.
Chun‐Yu Chen, Rui‐Xian Wang, Ken‐Pen Weng, Shih‐Ming Huang   +3 more
wiley   +1 more source

Can Artificial Intelligence Identify the Ideal Ablation Area for the Patients With Atypical Atrial Flutter? A Proof of Concept Study Using Developed Software

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Catheter ablation for atypical atrial flutter (AFL) is challenging owing to its complex circuit. Consequently, the success rate varies depending on the circuit complexity and the operator's level of experience. Objective This study aimed to create software using artificial intelligence to identify the critical isthmus of atypical ...
Motoki Amagasaki, Tadashi Hoshiyama, Takuma Meitoma, Masato Kiyama, Kenji Morihisa, Yuji Ogura, Kenichi Tsujita   +6 more
wiley   +1 more source

Dronedarone in high-risk permanent atrial fibrillation [PDF]

, 2011
BACKGROUND: Dronedarone restores sinus rhythm and reduces hospitalization or death in intermittent atrial fibrillation. It also lowers heart rate and blood pressure and has antiadrenergic and potential ventricular antiarrhythmic effects.
Afzal, R, Alings, M, Amerena, J, Atar, D, Avezum, Á, BaretCormel, L, Blomström, P, Borggrefe, M, Budaj, A, Camm, AJ, Chen, SA, Ching, CK, Chrolavicius, S, Commerford, P, Connolly, SJ, Dans, A, Davy, JM, Delacrétaz, E, Di Pasquale, G, Diaz, R, Dorian, P, Flaker, G, Golitsyn, S, GonzalezHermosillo, A, Granger, CB, Halperin, JL, Heidbüchel, H, Hohnloser, SH, Joyner, C, Kautzner, J, Kim, JS, Lanas, F, Lewis, BS, Merino, JL, Morillo, C, Murin, J, Narasimhan, C, Paolasso, E, Parkhomenko, A, Peters, NS, Sim, KH, Staiger, C, Stiles, MK, Tanomsup, S, Toivonen, L, Tomcsányi, J, TorpPedersen, C, Tse, HF, Vardas, P, Vinereanu, D, Weinling, E, Xavier, D, Yusuf, S, Zhu, J, Zhu, JR   +54 more
core   +1 more source

Etripamil Nasal Spray for Recurrent Paroxysmal Supraventricular Tachycardia Conversion: Results From the NODE‐303 Open‐Label Study

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Introduction Etripamil is a fast‐acting intranasally self‐administered calcium‐channel blocker developed for termination of paroxysmal supraventricular tachycardia (PSVT). Prior studies have demonstrated safety and efficacy of etripamil for PSVT termination following an initial medically supervised test dose during sinus rhythm. NODE‐303 is an
James E. Ip, Benoit Coutu, John H. Ip, Peter A. Noseworthy, Maria L. Parody, Farhad Rafii, Samuel F. Sears, Narendra Singh, Bruce S. Stambler, Naeem K. Tahirkheli, Juan Agudelo‐Uribe, Derek Hu, Silvia Shardonofsky, Muhammad B. Sheikh, Anita Holz, David B. Bharucha, A. John Camm   +16 more
wiley   +1 more source

Modulation by cAMP of a Slowly Activating Potassium Channel Expressed in \u3cem\u3eXenopus\u3c/em\u3e Oocytes [PDF]

, 1992
When expressed in the Xenopus oocyte, the minK protein induces a slowly activating voltage-dependent potassium current (Isk). We studied the modulation of this current by altering intracellular cAMP levels and found that the amplitude of Isk is ...
Blumenthal, Edward M, Kaczmarek, Leonard K.   +1 more
core   +1 more source

Effect of sotalol on heart rate, QT interval, and atrial fibrillation cycle length in horses with atrial fibrillation [PDF]

, 2018
Background: Based on its pharmacokinetic profile and electrophysiological effects in healthy horses, sotalol potentially could be used as a long-term PO antiarrhythmic drug in horses.
Anderson, Barrell, Brakel, Broux, Broux, Campbell, Clercq, Clercq, Clercq, Decloedt, Decloedt, Decloedt, Deem, Dufourni, Haugaard, Heliczer, January, Kerin, Lafuente-Lafuente, Loon, Mansour, McGurrin, Meurs, Milan, Pedersen, Rasmussen, Reef, Reef, Verheyen, Wang, Wijffels, Wijffels   +31 more
core   +2 more sources

New Russian antiarrhythmic agent nibentan: clinical effectiveness and pharmacokinetics in supraventricular arrhythmia management

Российский кардиологический журнал, 2007
Clinical effectiveness of a new Russian antiarrhythmic agent nibentan, Class III, was studied in various supraventricular arrhythmias. In total, 220 patients with atrial fibrillation (AF), atrial flutter (AFl), supraventricular tachycardia (SVT) and ...
A. E. Radzevich, V. G. Valiev, V. A. Gorshkov, E. M. Zeltyn, A. B. Bezprozvanny, E. N. Ostroumov, S. A. Appolonova   +6 more
doaj  

Blockade by NIP-142, an Antiarrhythmic Agent, of Carbachol-Induced Atrial Action Potential Shortening and GIRK1/4 Channel

Journal of Pharmacological Sciences, 2006
.: Mechanisms for the atria-specific action potential-prolonging action of NIP-142 ((3R*,4S*)-4-cyclopropylamino-3,4-dihydro-2,2-dimethyl-6-(4-methoxyphenylacetylamino)-7-nitro-2H-1-benzopyran-3-ol), a benzopyran compound that terminates experimental ...
Matsuda Tomoyuki, Ito Mie, Ishimaru Sayoko, Tsuruoka Noriko, Saito Tomoaki, Iida-Tanaka Naoko, Hashimoto Norio, Yamashita Toru, Tsuruzoe Nobutomo, Tanaka Hikaru, Shigenobu Koki   +10 more
doaj   +1 more source