Results 91 to 100 of about 19,342 (221)

New Russian antiarrhythmic agent nibentan: clinical effectiveness and pharmacokinetics in supraventricular arrhythmia management

open access: yesРоссийский кардиологический журнал, 2007
Clinical effectiveness of a new Russian antiarrhythmic agent nibentan, Class III, was studied in various supraventricular arrhythmias. In total, 220 patients with atrial fibrillation (AF), atrial flutter (AFl), supraventricular tachycardia (SVT) and ...
A. E. Radzevich   +6 more
doaj  

Modulation by cAMP of a Slowly Activating Potassium Channel Expressed in \u3cem\u3eXenopus\u3c/em\u3e Oocytes [PDF]

open access: yes, 1992
When expressed in the Xenopus oocyte, the minK protein induces a slowly activating voltage-dependent potassium current (Isk). We studied the modulation of this current by altering intracellular cAMP levels and found that the amplitude of Isk is ...
Blumenthal, Edward M   +1 more
core   +1 more source

Structure mirroring function: What's the ‘matter’ with the funny current?

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The ‘funny’ (If) current of cardiac pacemaker cells has been first identified in the late 1970s as a major mechanism in the generation and control of cardiac pacemaking. Decades of studies have since described the properties of the funny current and of its molecular components, HCN channels, in the heart and brain, providing the ...
Andrea Saponaro, Dario DiFrancesco
wiley   +1 more source

Chloral Hydrate Overdose Survived after Cardiac Arrest with Excellent Response to Intravenous β-blocker

open access: yesOman Medical Journal, 2019
Chloral hydrate (CH) poisoning is not commonly seen in the emergency department. CH is a commonly prescribed sedative agent for various day care procedures despite its toxic profile even when other safe sedative medications are available.
Shaik Karimulla Shakeer   +3 more
doaj   +1 more source

Pharmacology of Antiarrhythmics: Quinidine, Beta-Blockers, Diphenylhydantoin, Bretylium [PDF]

open access: yes, 1973
The electrophysiologic effects of the antiarrhythmic drugs, presented elsewhere in this symposium, form only one of the bases for the selection of a therapeutic agent in any given clinical situation.
Proctor, Jack D., Wasserman, Albert J.
core   +1 more source

RHYTHM-AF: design of an international registry on cardioversion of atrial fibrillation and characteristics of participating centers [PDF]

open access: yes, 2012
BACKGROUND Atrial fibrillation is a serious public health problem posing a considerable burden to not only patients, but the healthcare environment due to high rates of morbidity, mortality, and medical resource utilization. There are limited data on the
AJ Camm   +36 more
core   +3 more sources

Atrial fibrosis in atrial fibrillation: Mechanisms, mapping techniques and clinical applications

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Summary of key aspects of atrial fibrosis in atrial fibrillation, highlighting atrial fibrosis as a hallmark of atrial fibrillation (AF). (1) Different types of fibrosis (blue), illustrating reparative and reactive fibrosis; (2) fibrosis detection techniques (green), illustrating late gadolinium enhancement cardiac magnetic ...
Caterina Vidal Horrach   +8 more
wiley   +1 more source

HD Physiology Project-Japanese efforts to promote multilevel integrative systems biology and physiome research. [PDF]

open access: yes, 2017
The HD Physiology Project is a Japanese research consortium that aimed to develop methods and a computational platform in which physiological and pathological information can be described in high-level definitions across multiple scales of time and size.
for HD physiology project investigators   +3 more
core  

Mechanistic insights into sex differences in atrial electrophysiology and arrhythmia vulnerability through sex‐specific computational models

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sex‐specific models of the human atrial myocyte in normal sinus rhythm (nSR) and chronic atrial fibrillation (cAF) revealed increased alternans susceptibility in cAF males and DADs in females, driven primarily by ICaL and ryanodine receptor remodelling.
Nathaniel T. Herrera   +6 more
wiley   +1 more source

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