Results 111 to 120 of about 19,342 (221)
An intramolecular Mannich reaction (A/B/E/F rings) and intermolecular Diels–Alder reactions (C/D rings) afforded a cage‐like hexacyclic core skeleton of denudatine alkaloids. Derivatization of the hexacyclic intermediate enabled the first asymmetric total syntheses of four denudatine alkaloids: (–)‐cochlearenine, (–)‐macrocentrine, (–)‐dictizine, and (–
Shun Kawano +5 more
wiley +2 more sources
A QUANTUM CHEMICAL STUDY OF THE CONFORMATION OF ALINIDINE A NEW ANTIARRHYTHMIC AGENT [PDF]
The conformation of alinidine a new and specific bradycardic agent was studied using MNDO method. It has been found that the rotation of both phenyl and imidazoline ring of this compound is restricted.
doaj
Supraventricular Tachycardias Using Multiple Accessory Pathways
Three atrioventricular reciprocating tachycardias (AVRTs) using 3 accessory pathways (APs) occurred with the His bundle eliminated by the previous ablation. Two AVRTs using 2 right APs rotated reversely, and the other AVRT was one with a retrograde conduction through the left AP and anterograde conduction through the 2 right APs.
Takumi Yamada
wiley +1 more source
ABSTRACT Background Gender‐affirming testosterone therapy is one part of the standard of care for more than 1 million transgender adults in the United States. Testosterone therapy may influence the activities of drug‐metabolizing enzymes and transporters, but knowledge about its effect on the pharmacokinetics of other medications is limited.
Michiko Hunter +9 more
wiley +1 more source
ABSTRACT Severe obesity is associated with an increased cardiovascular risk. Metabolic‐bariatric surgery (MBS) can reduce the risk of cardiovascular events and mortality, potentially depending on weight loss composition. This study assessed the association between post‐MBS weight loss composition and major adverse cardiovascular events (MACE) and all ...
Malou A. H. Nuijten +8 more
wiley +1 more source
ABSTRACT Background Postoperative atrial arrhythmia (POAA) is common after lung transplant, but data on its implications and management are limited. This study assessed POAA incidence and timing, its association with mortality and rehospitalizations, and outcomes related to postoperative beta‐blocker use.
Daniel M. Chen +11 more
wiley +1 more source
Do antiarrhythmics prevent sudden death in patients with heart failure? [PDF]
Beta-blockers (class II antiarrhythmics) reduce sudden death and total mortality in patients with heart failure (strength of recommendation [SOR]: A, based on systematic reviews of randomized controlled trials).
Ball, Thomas A. +2 more
core
Abstract Aims To determine whether sodium glucose co‐transporter 2 inhibitors (SGLT2i) use, compared with dipeptidyl peptidase‐4 inhibitors (DPP4i) use, is associated with the risk of ventricular arrhythmias (VA) among patients with type 2 diabetes. Materials and Methods We conducted a population‐based cohort study using a prevalent new‐user design and
Wang‐Choi Tang +5 more
wiley +1 more source

