Results 131 to 140 of about 3,249,675 (219)

Nonsteroidal Anti‐Inflammatory Drugs as Modulators of Cation Channels: Fenamates Repurposing in Channelopathies

open access: yesChemMedChem, Volume 20, Issue 20, October 15, 2025.
Beyond their established role as nonsteroidal anti‐inflammatory drugs (NSAIDs), fenamates (niflumic, flufenamic, mefenamic, meclofenamic, and tolfenamic acids) have recently been identified as modulators of cationic ion channels. This review highlights their differential effects on ion channel activity and explores their potential for repurposing in ...
Paola Laghetti   +4 more
wiley   +1 more source

Dronedarone for the treatment of atrial fibrillation and atrial flutter: approval and efficacy

open access: yesVascular Health and Risk Management, 2010
Deborah Wolbrette, Mario Gonzalez, Soraya Samii, Javier Banchs, Erica Penny-Peterson, Gerald NaccarelliPenn State Heart and Vascular Institute, Penn State Milton S Hershey Medical Center, Hershey, Pennsylvania, USAAbstract: Dronedarone, a new Class III ...
Deborah Wolbrette   +3 more
doaj  

MK-0448, a Specific Kv1.5 Inhibitor: Safety, Pharmacokinetics and Pharmacodynamic Electrophysiology in Experimental Animal Models and in Humans. [PDF]

open access: yes, 2012
BACKGROUND: -We evaluated the viability of I(Kur) as a target for maintenance of sinus rhythm in patients with a history of atrial fibrillation through the testing of MK-0448, a novel I(Kur) inhibitor.
Bilodeau, Mark T   +13 more
core   +1 more source

Efficacy and safety of 1C class antiarrhythmic agent (propafenone) for supraventricular arrhythmias in septic shock compared to amiodarone: protocol of a prospective randomised double-blind study. [PDF]

open access: yesBMJ Open, 2019
Balik M   +16 more
europepmc   +1 more source

Ventricular Tachycardia Ablation versus Escalation of Antiarrhythmic Drugs.

open access: yesNew England Journal of Medicine, 2016
J. Sapp   +19 more
semanticscholar   +1 more source

Effect of the antiarrhythmic agent moricizine on survival after myocardial infarction.

open access: yesNew England Journal of Medicine, 1992
W. Rogers   +383 more
semanticscholar   +1 more source

Electrophysiological Effects of a New Antiarrhythmic Agent, Flecainide, on the Intact Canine Heart

open access: yesJournal of Cardiovascular Pharmacology, 1979
A. Hodess   +3 more
semanticscholar   +1 more source

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