New Antiarrhythmic Agent to Stabilize Functional Activity of Rat Heart Sinus Node Cardiomyocytes [PDF]
Research Results in Pharmacology, 2020 Introduction: The aim of this study was to explore the antiarrhythmic activity of the new antiarrhythmic drug, succinic acid ester of 5-hydroxyadamantane-2-one (ADK-1110) and its effect on the functional activity of rat heart sinus node.
Ruben S. Mirzoyan +9 more
doaj +3 more sources
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Adenosine induced coronary spasm – A rare presentation
Indian Heart Journal, 2014 Adenosine is commonly used as a pharmacological agent in myocardial perfusion imaging, as an antiarrhythmic agent, and in Cath Lab. during PCI for treating no reflow phenomenon. Coronary spasm has been reported following adenosine injection during stress
P. Arora, V. Bhatia, M. Arora, U. Kaul
doaj +1 more source
Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle [PDF]
, 2005 Background - Although pharmacological block of the slow, delayed rectifier potassium current (I-Ks) by chromanol 293B, L-735,821, or HMR-1556 produces little effect on action potential duration (APD) in isolated rabbit and dog ventricular myocytes, the ...
Biliczki, Péter +10 more
core +1 more source
Unambiguous Assignment of the 1H- and 13C-NMR Spectra of Propafenone and a Thiophene Analogue
Molecules, 2001 Full and unambiguous asssignment of all 1H- and 13C-NMR resonances of the free bases as well as the hydrochloride salts of the antiarrhythmic agent propafenone and a thiophene analogue in different solutions (DMSO-d6, CDCl3) is reported.
Wolfgang Holzer
doaj +1 more source
Anti-Trypanosoma cruzi action of a new benzofuran derivative based on amiodarone structure [PDF]
, 2018 Chagas disease is a neglected tropical affection caused by the protozoan parasite Trypanosoma cruzi. There is no current effective treatment since the only two available drugs have a limited efficacy and produce side effects.
Benaim, Gustavo +4 more
core +1 more source
Allicin disrupts cardiac Cav1.2 channels via trafficking
Pharmaceutical Biology, 2019 Context: Allicin is a potential antiarrhythmic agent. The antiarrhythmic properties of allicin rely on its blockade of various cardiac ion channels.
Dan Han +5 more
doaj +1 more source
Journal of Arrhythmia, 2011 Introduction: Bepridil is effective for atrial fibrillation (AF), but it can induce torsades de pointes. Thus we examined the efficacy and safety of bepridil when started at 100 mg/day for AF after failed electrical cardioversion (EC).
Yasuyuki Egami, MD +7 more
doaj +1 more source
Atrial remodeling in permanent atrial fibrillation : Mechanisms and pharmacological implications [PDF]
, 2013 Atrial fibrillation (AF), the most prevalent rhythm disorder in clinical practice, is currently significantly contributing to morbidity and mortality of the ageing population.
Fazekas, Tamás +3 more
core +1 more source
Lidocaine Infusion: An Antiarrhythmic With Neurologic Toxicities
Cureus, 2022 As a renowned local anesthetic agent of choice, lidocaine is also a class 1b antiarrhythmic agent that is primarily used for the treatment of ventricular arrhythmias.
Y. Daraz, Omar H Abdelghffar
semanticscholar +1 more source