AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
New progress in understanding the cellular mechanisms of anti-arrhythmic drugs
Open Life Sciences, 2018 Antiarrhythmic drugs are widely used, however, their efficacy is moderate and they can have serious side effects. Even if catheter ablation is effective for the treatment of atrial fibrillation and ventricular tachycardia, antiarrhythmic drugs are still ...
An Zhe +4 more
doaj +1 more source
Therapeutic drug monitoring: antiarrhythmic drugs [PDF]
British Journal of Clinical Pharmacology, 1998 Antiarrhythmic agents are traditionally classified according to Vaughan Williams into four classes of action. Class I antiarrhythmic agents include most of the drugs traditionally thought of as antiarrhythmics, and have as a common action, blockade of the fast‐inward sodium channel on myocardium. These agents have a very significant toxicity, and while
T J, Campbell, K M, Williams
openaire +4 more sources
Sex‐specific activation of SK current by isoproterenol facilitates action potential triangulation and arrhythmogenesis in rabbit ventricles [PDF]
, 2018 Sex has a large influence on cardiac electrophysiological properties. Whether sex differences exist in apamin‐sensitive small conductance Ca2+‐activated K+ (SK) current (IKAS) remains unknown.
Chen, Mu +10 more
core +1 more source
The year in cardiology: arrhythmias and pacing. [PDF]
, 2020 During this last year, there has been much progress with regard to anticoagulant and ablation therapy for atrial fibrillation (AF). Apart from recently issued European Society of Cardiology Guidelines for the management of patients with supraventricular ...
Calkins, H +4 more
core +4 more sources
Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle [PDF]
, 2005 Background - Although pharmacological block of the slow, delayed rectifier potassium current (I-Ks) by chromanol 293B, L-735,821, or HMR-1556 produces little effect on action potential duration (APD) in isolated rabbit and dog ventricular myocytes, the ...
Biliczki, Péter +10 more
core +1 more source
Journal of Pharmacy and Bioallied Sciences, 2017 Cardiac arrhythmias are a major cause of morbidity and mortality across the world. Learning the science behind the use of antiarrhythmic drugs is essential for all medical graduates. However, many antiarrhythmic drugs are available, and most of them have
Ameya A Hasamnis, Aditya Arya
doaj +1 more source
Effect of catheter ablation on quality of life in patients with atrial fibrillation and its correlation with arrhythmia outcome [PDF]
, 2015 Objective To assess the effect of catheter ablation on atrial fibrillation (AF) symptoms and quality of life (QoL). Methods Patients with AF scheduled for ablation were recruited.
Bourke, John P +6 more
core +1 more source
Frontiers in Cardiovascular Medicine, 2022 ObjectiveTo evaluate the effectiveness and safety of Linggui Zhugan decoction (LZD) as an adjunct treatment of premature contraction in patients with coronary heart disease.MethodsPubMed, Embase, Web of Science, ClinicalTrials.gov Cochrane Library ...
Longkun Liu +7 more
doaj +1 more source
Antiarrhythmic Drug Therapy in Arrhythmogenic Right Ventricular Cardiomyopathy
Biomedicines, 2023 Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a heritable progressive myocardial disorder that predisposes patients to ventricular arrhythmias and sudden cardiac death.
Sean P. Gaine, Hugh Calkins
doaj +1 more source