Results 41 to 50 of about 1,059,639 (249)
Therapy for patient with atrial fibrillation: in search of a balance between efficacy and safety
Клинический разбор в общей медицинеThis paper analyzes aspects of the efficacy and safety of antiarrhythmic drugs in the treatment of atrial fibrillation. It considers drug-drug interactions of antiarrhythmics with other drugs, especially in the near circle, i.e.
Yakov G. Bozhko +2 more
doaj +1 more source
Effects of Antiarrhythmic Drugs on Apoptotic Pathways in H9c2 Cardiac Cells
Journal of Pharmacological Sciences, 2006 .: Antiarrhythmic drugs may induce cellular apoptosis in the heart. By using representatives of 5 different categories of antiarrhythmic drugs, that is, pilsicainide, propranolol, nifekalant, verapamil, and amiodarone, we investigated whether these ion ...
Shojiro Isomoto +5 more
doaj +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 955-967, April 2025.Abstract Wild‐type transthyretin amyloid cardiomyopathy (ATTRwt‐CM) is a progressive and infiltrative cardiac disorder that may cause fatal consequences if left untreated. The estimated survival time from diagnosis is approximately 3–6 years. Because of the non‐specificity of initial symptom manifestation and insufficient awareness among treating ...
Yasuhiro Izumiya +9 more
wiley +1 more source
Management of tachyarrhythmia during pregnancy
Türk Kardiyoloji Derneği Arşivi, 2017 Maternal tachyarrhythmia is a common complication during pregnancy due to hormonal changes that enhance pre-existing arrhythmias or induce new arrhythmias in the presence of congenital heart defects in pregnant females. Presence of tachyarrhythmia during
Emily Ann Enderlin +4 more
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Frontiers in Physiology, 2022 Background: Carbon monoxide (CO) is gaining increased attention in air pollution-induced arrhythmias. The severe cardiotoxic consequences of CO urgently require effective pharmacotherapy to treat it.
Huasen Jiang +6 more
doaj +1 more source
The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle
ESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley +1 more source
Frontiers in Tropical Diseases, 2023 The repurposing of approved drugs is an appealing method to fast-track the development of novel therapies for neglected diseases. Amiodarone and dronedarone, two approved antiarrhythmic agents, have been reported to have potential for the management of ...
Amanda F. Francisco +16 more
doaj +1 more source
ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi +6 more
wiley +1 more source
Mexiletine: Antiarrhythmic mechanisms, emerging clinical applications and mortality
, 2023 Mexiletine, a class Ib antiarrhythmic drug, exhibits its major antiarrhythmic effect via inhibition of the fast and late Na currents in myocardial tissues that are dependent on the opening of Na channels for their excitation.
Tse, Gary +5 more
core +1 more source
Elevation of ventricular defibrillation threshold in dogs by antiarrhythmic drugs [PDF]
, 1979 Effects of antiarrhythmic drugs upon the threshold delivered energy (TDE) and threshold peak current (TPC) for electrical ventricular defibrillation by damped sinusoidal shocks were investigated in 25 pentobarbital-anesthetized dogs.
Babbs, Charles F +4 more
core +1 more source