Results 51 to 60 of about 42,366 (268)

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga   +20 more
wiley   +1 more source

Impact of Antiarrhythmic Drugs on the Outcome of Short QT Syndrome

open access: yesFrontiers in Pharmacology, 2019
Short QT syndrome (SQTS) is associated with sudden cardiac arrest. There are limited data on the impact of antiarrhythmic drugs on the outcome of SQTS.Materials and Methods: We studied data that describe the clinical outcome of 62 SQTS patients treated ...
Ibrahim El-Battrawy   +19 more
doaj   +1 more source

Transplacental Treatment of Fetal Tachyarrhythmia: Current Trends and Future Perspectives

open access: yesFuture Pharmacology, 2023
Fetal arrhythmias complicate 1% of pregnancies. Although most of them have a benign and intermittent course, sustained fetal tachyarrhythmias constitute an emerging situation, which is associated with high fetal morbidity and mortality.
Ángel Chimenea   +3 more
doaj   +1 more source

Role of pharmacotherapy in Brugada syndrome [PDF]

open access: yes, 2004
In patients who undergo aborted sudden cardiac death or syncope of unknown origin (symptomatic Brugada syndrome), no one argues that the implantation of an ICD is the first-line therapy regardless of the findings of the EP study.
Tsuchiya, Takeshi
core   +1 more source

Catheter ablation of atrial fibrillation : radiofrequency catheter ablation for redo procedures after cryoablation [PDF]

open access: yes, 2013
Aim: To evaluate the effectiveness of two different strategies using radiofrequency catheter ablation for redo procedures after cryoablation of atrial fibrillation. Methods: Thirty patients (paroxysmal atrial fibrillation: 22 patients, persistent atrial
Gramley, Felix, Kettering, Klaus
core   +1 more source

Impact of empiric potassium supplementation on mortality, sudden cardiac arrest and stroke in furosemide initiators

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim A prior non‐randomized study suggests that potassium supplementation may improve survival among furosemide initiators, and a randomized trial suggests that salt substitutes containing potassium might lower stroke risk. We conducted a retrospective cohort study using health‐care data to confirm or refute these associations among new users of ...
Thanh Phuong Pham Nguyen   +8 more
wiley   +1 more source

The European Network for Translational Research in Atrial Fibrillation (EUTRAF): objectives and initial results. [PDF]

open access: yes, 2015
Atrial fibrillation (AF) is the most common sustained arrhythmia in the general population. As an age-related arrhythmia AF is becoming a huge socio-economic burden for European healthcare systems. Despite significant progress in our understanding of the
Antoons, G   +22 more
core   +3 more sources

Drug Critical Limits for Urgent Physician Notification

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Critical limits represent quantitative decision thresholds for drugs that require immediate clinician notification and potential life‐saving intervention. United States hospitals lack a national standard for drug critical limits. We collected critical limits from 417 US hospitals across all 50 states and Washington, D.C.; of these, 411 maintained drug ...
Elina Kuang   +3 more
wiley   +1 more source

ADJUSTMENT OF PHARMACOLOGICAL ANTIARRHYTHMIC THERAPY IN PATIENTS WITH PAROXYSMAL ATRIAL FIBRILLATION DURING SERIAL TESTING OF ANTIARRHYTHMIC DRUGS WITH TRANSESOPHAGEAL ELECTROPHYSIOLOGICAL STUDIES

open access: yesРоссийский кардиологический журнал, 2003
The work has studied opportunities for ТЕ EPS in serial testing of antiarrhythmic drugs testing to prevent recurrent arrhythmia in patients with atrial fibrillation.
K. A. Skiba, V. V. Petry, V. A. Sulimov
doaj  

Efficacy and Safety of Catheter Ablation vs Antiarrhythmic Drugs as Initial Therapy for Management of Symptomatic Paroxysmal Atrial Fibrillation: A Meta-Analysis

open access: yesReviews in Cardiovascular Medicine, 2022
Background: Catheter ablation is an effective treatment for atrial fibrillation (AF), primarily performed in patients who fail antiarrhythmic drugs. Whether early catheter ablation, as first-line therapy, is associated with improved clinical outcomes ...
Aminah Abdul Razzack   +16 more
doaj   +1 more source

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