Results 101 to 110 of about 41,794 (337)

Role of pharmacotherapy in Brugada syndrome [PDF]

, 2004
In patients who undergo aborted sudden cardiac death or syncope of unknown origin (symptomatic Brugada syndrome), no one argues that the implantation of an ICD is the first-line therapy regardless of the findings of the EP study.
Tsuchiya, Takeshi
core   +1 more source

Cellular and molecular cross‐talk in atrial fibrillation: The role of non‐cardiomyocytes in creating an arrhythmogenic substrate

The Journal of Physiology, EarlyView.
Abstract figure legend Illustration of cellular and molecular cross‐talk in atrial fibrillation. Left: a schematic of cardiac tissue showing cardiomyocytes, fibroblasts, adipocytes, inflammatory cells and the coagulation system. Right: direct and indirect cross‐talk between different cell types, with the impact of direct cross‐talk on action potential (
Zhenyu Dong, Ruben Coronel, Joris R. de Groot   +2 more
wiley   +1 more source

Ventricular tachycardia characteristics and outcomes with catheter ablation vs. antiarrhythmic therapy: insights from the VANISH trial. [PDF]

Europace, 2022
Deyell MW, Doucette S, Parkash R, Nault I, Gula L, Gray C, Gardner M, Sterns LD, Healey JS, Essebag V, Sapp JL.   +10 more
europepmc   +1 more source

Association of Air Pollution with Increased Incidence of Ventricular Tachyarrhythmias Recorded by Implanted Cardioverter Defibrillators [PDF]

, 2005
Epidemiologic studies have demonstrated a consistent link between sudden cardiac deaths and particulate air pollution. We used implanted cardioverter defibrillator (ICD) records of ventricular tachyarrhythmias to assess the role of air pollution as a ...
David Q. Rich, Diane R. Gold, Douglas W. Dockery, Heike Luttmann-Gibson, Joel D. Schwartz, Mark S. Link, Murray A. Mittleman, Myerburg RJ, Petros Koutrakis, Richard L. Verrier   +9 more
core   +2 more sources

Structure mirroring function: What's the ‘matter’ with the funny current?

The Journal of Physiology, EarlyView.
Abstract figure legend The ‘funny’ (If) current of cardiac pacemaker cells has been first identified in the late 1970s as a major mechanism in the generation and control of cardiac pacemaking. Decades of studies have since described the properties of the funny current and of its molecular components, HCN channels, in the heart and brain, providing the ...
Andrea Saponaro, Dario DiFrancesco
wiley   +1 more source

THE UNRESOLVED ISSUES AND MODERN VIEW ON ATRIAL FIBRILLATION PATIENTS MANAGEMENT

Российский кардиологический журнал, 2017
T he article focuses on the main debating and unresolved issues on atrial fibrillation patients therapy, e.g. anticoagulation, antiarrhythmic, intervention and surgical tactics.
D. V. Losik, S. A. Bayramova, E. A. Pokushalov, I. L. Mikheenko, V. V. Shabanov, A. B. Romanov   +5 more
doaj   +1 more source

Mechanisms and risk factors for proarrhythmia with type Ia compared with Ic antiarrhythmic drug therapy. [PDF]

, 1989
J H Levine, Joel Morganroth, Alan H. Kadish   +2 more
openalex   +1 more source

Computational modelling of the pro‐ and antiarrhythmic effects of atrial high rate‐dependent trafficking of small‐conductance calcium‐activated potassium channels

The Journal of Physiology, EarlyView.
Abstract figure legend Small‐conductance calcium‐activated potassium (SK) channels are important for atrial repolarization and can be targeted for atrial‐specific antiarrhythmic treatments. We developed a computational model with a calcium sensor to study the effects of increased pacing rate (5 Hz), which enhances SK‐channel gating and forward ...
Stefan Meier, Dobromir Dobrev, Paul G. A. Volders, Jordi Heijman   +3 more
wiley   +1 more source

Antiarrhythmic Drug Combination Therapy

Cardiac Electrophysiology Review, 1998
Enhanced antiarrhythmic ef~cacy may be achieved using a number of theoretic strategies. First, a drug that prolongs “time to ~rst recurrence” of a symptomatic arrhythmia could be combined with a second drug that changes the character of the recurrent arrhythmia from a hemodynamically compromising episode to one that produces few symptoms and no ...
openaire   +3 more sources

Sodium-glucose transporter 2 inhibitors and their antiarrhythmic role: New insights and future perspective

Acta Marisiensis - Seria Medica
Sodium-glucose transporter 2 inhibitors have been identified as pleiotropic pharmacological agents with demonstrated efficacy in a wide range of pathologies.
Prația-Aron Diana-Ioana, Cozac Dan-Alexandru, Scridon Alina   +2 more
doaj   +1 more source