Results 111 to 120 of about 2,377,916 (241)

The Effect of Sacubitril/Valsartan on Supraventricular and Ventricular Arrhythmias in Patients With Heart Failure

Annals of Noninvasive Electrocardiology
Background Patients with heart failure with reduced ejection fraction (HFrEF) frequently experience electrical disturbances, such as ventricular or atrial fibrillation (AF).
Alireza Arzhangzadeh, Mohammad Hossein Nikoo, Majid Haghjoo, Fatemeh Rasekh, Shayan Shojaei, Asma Mousavi, Salma Nozhat, Roozbeh Narimani‐Javid, Helia Bazroodi, Sana Neisi, Mitra Mojibpour, Mohammad Abedini, Saghi Eslamzadeh, Hamed Bazrafshan Drissi, Sasan Shafiei   +14 more
doaj   +1 more source

Present and future of antiarrhythmic therapy for atrial fibrillation: A review

Consilium Medicum
Despite the emergence and active development of interventional methods for the treatment of arrhythmias, to date, the use of antiarrhythmic drugs to recover and maintain sinus rhythm is the most significant and in demand in patients with paroxysmal and ...
Aida I. Tarzimanova
doaj   +1 more source

Personalized Antiarrhythmic Therapy Using a Self-Managed Daily-ECG Device. [PDF]

Diagnostics (Basel), 2023
Mattei E, Lino S, Censi F, Calcagnini G, Calò L.   +4 more
europepmc   +1 more source

Mechanistic insights into sex differences in atrial electrophysiology and arrhythmia vulnerability through sex‐specific computational models

The Journal of Physiology, EarlyView.
Abstract figure legend Sex‐specific models of the human atrial myocyte in normal sinus rhythm (nSR) and chronic atrial fibrillation (cAF) revealed increased alternans susceptibility in cAF males and DADs in females, driven primarily by ICaL and ryanodine receptor remodelling.
Nathaniel T. Herrera, Haibo Ni, Charlotte E. R. Smith, Yixuan Wu, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +6 more
wiley   +1 more source

Atrial fibrillation-associated electrical remodelling in human induced pluripotent stem cell-derived atrial cardiomyocytes: a novel pathway for antiarrhythmic therapy development. [PDF]

Cardiovasc Res, 2023
Seibertz F, Rubio T, Springer R, Popp F, Ritter M, Liutkute A, Bartelt L, Stelzer L, Haghighi F, Pietras J, Windel H, Pedrosa NDI, Rapedius M, Doering Y, Solano R, Hindmarsh R, Shi R, Tiburcy M, Bruegmann T, Kutschka I, Streckfuss-Bömeke K, Kensah G, Cyganek L, Zimmermann WH, Voigt N.   +24 more
europepmc   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source

The interplay between dynamic regulation of ion‐channel gating and trafficking in cardiac arrhythmogenesis

The Journal of Physiology, EarlyView.
Abstract figure legend Cardiac cellular electrophysiology is modulated by multiple factors, including temperature, extracellular K+, heart rate/pacing frequency, and drugs. These modulators can have distinct effects on ion‐channel gating and transcription/trafficking over time.
Stefan Meier, Anna S. Savchenko, Paul G. A. Volders, Jordi Heijman   +3 more
wiley   +1 more source

Antiarrhythmic Treatment in Heart Failure

<jats:title>Abstract   </jats:title><jats:sec> <jats:title>Purpose of Review</jats:title> <jats:p>Arrhythmias are common in patients with heart failure (HF) and are associated with a ...
Eckardt, Lars, Ellermann, Christian, Könemann, Hilke, Frommeyer, Gerrit, Güler-Eren, Sati   +4 more
core   +1 more source

Regional electrical differences and arrhythmia in the rat atria: Role of sympathetic nerve distribution and function

The Journal of Physiology, EarlyView.
Abstract figure legend Atrial fibrillation commonly develops in the left atrium and pulmonary veins (PVs), and can be triggered by sympathetic nerve activity. Here, we examined regional atrial differences in sympathetic nerve distribution and function in the rat.
James Saleeb‐Mousa, Manish Kalla, Neil Herring, Christopher O'Shea, Andrew M. Coney, Keith L. Brain, Andrew P. Holmes   +6 more
wiley   +1 more source

Development of Antiarrhythmic Therapy-Resistant Ventricular Tachycardia, Ventricular Fibrillation, and Premature Ventricular Contractions in a 15-Year-Old Patient. [PDF]

J Pediatr Intensive Care, 2022
Yozgat CY, Yesilbas O, Iscan A, Yurtsever I, Temur HO, Bayramova N, Ergun G, Tekin N, Yozgat Y.   +8 more
europepmc   +1 more source