Results 121 to 130 of about 2,377,916 (241)

Treatment planning study comparing proton therapy, RapidArc and intensity modulated radiation therapy for a synchronous bilateral lung cancer case

, 2014
Purpose: The main purpose of this study is to perform a treatment planning study on a synchronous bilateral non-small cell lung cancer case using three treatment modalities: uniform scanning proton therapy, RapidArc, and intensity modulated radiation ...
Zheng, Yuanshui; Department of Medical Physics, ProCure Proton Therapy Center, Oklahoma City, OK, USA., Zhao, Li; Department of Medical Physics, ProCure Proton Therapy Center, Oklahoma City, OK, USA., Risalvato, Dina; Department of Medical Dosimetry, ProCure Proton Therapy Center, Oklahoma City, Oklahoma, USA., Vargas, Carlos; Radiation Oncology, Proton Collaborative Group (PCG), Bloomington, Indiana, USA., Rana, Suresh; Department of Medical Physics, ProCure Proton Therapy Center, Oklahoma City, OK, USA., Pokharel, Shyam; Department of Medical Physics, 21st Century Oncology, Fort Myers, Florida, USA., Cersonsky, Nancy; Department of Radiation Oncology, ProCure Proton Therapy Center, Oklahoma City, Oklahoma, USA.   +6 more
core   +1 more source

hERG1 channels and potential therapeutics for long QT syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend Prolonged QT results from hERG1 channel dysfunction. (A) Physiological anterograde trafficking of hERG1 channels to the plasma membrane, leading to a normal electrocardiogram. (B) Prolonged QT results from the presence of fewer hERG1 channels on the plasma membrane due to decreased anterograde trafficking or reduced function due ...
Elizabeth H. Schneider, Kelly A. Aromolaran, Michael C. Sanguinetti, Ademuyiwa S. Aromolaran   +3 more
wiley   +1 more source

Paroxysmal atrioventricular nodal reentrant tachycardias: epidemiology, clinical picture, diagnostics, treatment (review) [PDF]

Саратовский научно-медицинский журнал, 2012
Nowadays paroxysmal AV nodal reentrant tachycardia (AVNRT) is one of the most widespread arrhythmias. In most cases AVRNT is a recurrent process, and it worsens the life quality of such patients, reduces their workability and increases the incidence of ...
Morozov I.A., FurmanN.V., Rakovskaya I.M., Oleynik G.S., Korobkov E.A.   +4 more
doaj  

Surgical Removal of Residual Tumor Masses in Patients Undergoing Targeted Therapy for EGFR‐Mutated Locally Advanced or Metastatic Lung Cancer

International Journal of Cancer, Volume 159, Issue 9, Page 2244-2261, 1 November 2026.
Non‐small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations often exhibit significant tumor reduction following tyrosine kinase inhibitor (TKI) therapy. Residual tumors frequently remain, however, leading to drug resistance and disease progression.
Fedor Moiseenko, Daniil Stroyakovskiy, Evgeniy Levchenko, Mikhail Fedyanin, Albina Gabina, Ani Oganesian, Sergey Belukhin, Maria Stepanova, Ekaterina Stepanova, Elizaveta Artemyeva, Alexander Myslik, Nikita Volkov, Alexei Bogdanov, Tatiana Shuginova, Kirill Kryukov, Valeria Kheinshtein, Arif Allakhverdiev, Ivan Zaberegniy, Yana Akhmadiyarova, Mikhail Popov, Anastasiya Danilova, Dmitriy Sehniaidze, Nikita Savelov, Nikita Levchenko, Evgeniy Slugin, Olga Lopushanskaya, Ekaterina Kuligina, Svetlana Aleksakhina, Aglaya Iyevleva, Alexandr Ivantsov, Vladimir Moiseyenko, Evgeny Imyanitov   +31 more
wiley   +1 more source

Antiarrhythmic drugs and the importance of beat rate variability in clinical practice

This thesis explores the importance of antiarrhythmic drugs in the treatment of arrhythmia with a focus on evidence-based clinical practice. Although a lot of new drugs have been added to a modernized classification of antiarrhythmic drugs, most of them ...
Khong, Minh Dat
core  

End‐Of‐Life Care in a Cardiac Intensive Care Unit: A Retrospective Analysis of Interventions During the Last 48 Hours

Nursing in Critical Care, Volume 31, Issue 6, November 2026.
ABSTRACT Background Palliative care in intensive care units should be planned jointly with patients and their families and documented in medical records. Proximity to death should prompt reassessment of the therapeutic strategy. Aim To analyse the interventions performed during the last 48 h in patients who died in the cardiac intensive care unit ...
Eduardo Tavares Gomes, Larissa Braga Celes, Geovana Aparecida dos Reis Cirino   +2 more
wiley   +1 more source

Application of Plasma Level Determinations to Antiarrhythmic Drug Management Integration with Various End-points of Therapy

Therapeutic effectiveness of antiarrhythmic agents, defined as the prevention of lethal or potentially lethal arrhythmias, must incorporate considerations of 3 elements: the forms and/or frequency of chronic ventricular arrhythmias, as well as the ...
Kessler, Kenneth M, Saoudi, Nadir, Castellanos, Agustin, Zaman, Liaqat, Myerburg, Robert J, Trohman, Richard G   +5 more
core   +1 more source

Glucagon‐Like Peptide‐1 Agonists and the Incidence of Atrial Fibrillation in Obese Patients With Heart Failure With Preserved Ejection Fraction and No Diabetes

Journal of Arrhythmia, Volume 42, Issue 5, October 2026.
Among obese, non‐diabetic patients with HFpEF, GLP‐1 RA therapy was not significantly associated with incident atrial fibrillation but was associated with lower all‐cause mortality. Prospective studies are needed to clarify the potential role of GLP‐1 RAs in AF prevention. ABSTRACT Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) reduce
Farah Rassam, Esteban Kosak Lopez, Sarah Sass, Thitiphan Srikulmontri, Evan Isaacs, John Malin, Phuuwadith Wattanachayakul, Olayinka Afolabi‐Brown   +7 more
wiley   +1 more source

Association Between the Change in Interleukin‐6 Levels and Early Recurrence of Atrial Fibrillation: A Comparison of Pulsed Field Ablation and Radiofrequency Ablation

Journal of Arrhythmia, Volume 42, Issue 5, October 2026.
Despite causing greater myocardial injury and hemolysis, pulsed field ablation induces significantly less systemic inflammation than radiofrequency ablation. This reduced inflammatory response is independently associated with a lower incidence of early atrial fibrillation recurrence.
Ken Watanabe, Takanori Arimoto, Mashu Toyoshima, Kyoko Koyama, Yuta Kobayashi, Naoaki Hashimoto, Masafumi Watanabe   +6 more
wiley   +1 more source

Clinical Vulnerability Refines Rhythm‐Related Outcomes in Older Patients Undergoing Pulmonary Vein Isolation for Atrial Fibrillation: An Observational Cohort Study

Journal of Arrhythmia, Volume 42, Issue 5, October 2026.
In patients undergoing pulmonary vein isolation, age ≥ 75 years was associated with greater recurrence‐related rhythm intervention. However, outcomes varied markedly among older adults. A simple score incorporating persistent AF, heart failure, chronic kidney disease, and valve disease identified elderly patients with low or high clinical vulnerability.
Yazan Mohsen, Jascha Fernholz, Lucas Steffens, Iryna Novikov, Shreeram Sabareesan, Ishan Vatsaraj, Kensuke Sakata, Moritz Knitter, Henning Horlitz, Marc Horlitz, Mustafa Zakkar, Riyaz Somani, G. Andre Ng, Dennis Rottländer, Florian Stöckigt, Ibrahim Antoun   +15 more
wiley   +1 more source