Results 141 to 150 of about 17,282 (226)
The Journal of Physiology, EarlyView.Abstract figure legend Sex‐specific models of the human atrial myocyte in normal sinus rhythm (nSR) and chronic atrial fibrillation (cAF) revealed increased alternans susceptibility in cAF males and DADs in females, driven primarily by ICaL and ryanodine receptor remodelling.
Nathaniel T. Herrera +6 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Mitochondrial SK channel enhancement reduces cardiac arrhythmia trigger. Spontaneous sarcoplasmic reticulum (SR) Ca2+ release via hyperactive RyR2s underlies an increased arrhythmia trigger, promoting early and delayed afterdepolarizations during stress. Hyperactive RyR2s causes rise in cytosolic [Ca2+] during diastole. Clearance
Dmitry Terentyev +7 more
wiley +1 more source
Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes
The Journal of Physiology, EarlyView.Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière +6 more
wiley +1 more source
Journal of Arrhythmia, Volume 42, Issue 3, June 2026.Efficacy and safety of a fixed low‐power, long‐duration radiofrequency catheter ablation of ventricular arrhythmias originating from the left ventricular summit. ABSTRACT Background Radiofrequency catheter ablation (RFCA) of ventricular arrhythmias originating from the left ventricular summit (LVS‐VAs) remains challenging.
Takuro Masuda +10 more
wiley +1 more source
Journal of Internal Medicine, Volume 299, Issue 6, Page 754-775, June 2026.Abstract Background Effectively identifying individuals exposed to drug underuse, overuse and potentially inappropriate medication (PIM) in older adults is essential for minimizing preventable drug‐related harms. Methods We analysed data from 54,296 individuals aged 60–74 years from the German National Cohort (NAKO).
Miriam Degen +18 more
wiley +1 more source
Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks
British Journal of Clinical Pharmacology, Volume 92, Issue 5, Page 1287-1308, May 2026.The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou +2 more
wiley +1 more source
Flecainide‐Induced Interstitial Lung Disease: A Case Report and Review of the Literature
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT This case describes a rare adverse effect in which the subject developed interstitial lung disease after initiating a class IC antiarrhythmic, flecainide. There is no current treatment recommendation for flecainide‐induced interstitial lung disease.
Elizabeth Jenkins +2 more
wiley +1 more source
Possible Deslanoside‐Induced Left Posterior Fascicular Ventricular Tachycardia: A Case Report
Annals of Noninvasive Electrocardiology, Volume 31, Issue 3, May 2026.A 73‐year‐old man with paroxysmal AF and no structural heart disease who developed left posterior fascicular ventricular tachycardia (LPFVT) shortly after intravenous Deslanoside administration for rate control. Highlights: cardiac glycosides, though effective for rate control, may occasionally precipitate Purkinje‐related ventricular tachycardia ...
Zhang Wenjun, Chen Yao
wiley +1 more source