Results 151 to 160 of about 17,282 (226)
Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway
British Journal of Pharmacology, Volume 183, Issue 9, Page 1939-1957, May 2026.Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu +4 more
wiley +1 more source
Opening closed inward rectifier potassium channel doors
British Journal of Pharmacology, Volume 183, Issue 10, Page 2197-2218, May 2026.Inwardly rectifying potassium (KIR) channels are essential regulators of membrane potential in excitable and non‐excitable tissues. Although KIR channels exhibit a biophysical preference for potassium influx due to voltage‐dependent block of outward current by polyamines and Mg2+, under physiological conditions, they predominantly mediate K+ efflux ...
Anna Stary‐Weinzinger +3 more
wiley +1 more source
Prehospital Risk Stratification Using Unsupervised Machine Learning in STEMI
European Journal of Clinical Investigation, Volume 56, Issue 5, May 2026.Machine learning identified three phenotypes with 30‐day mortality of 3.4%, 22.1%, and 75%. Phenotype‐2 reveals an "occult high‐risk" group: hemodynamically stable yet six‐fold higher mortality. ABSTRACT Background ST‐elevation myocardial infarction (STEMI) exhibits substantial clinical heterogeneity complicating prehospital risk stratification ...
Ana Ramos‐Rodríguez +7 more
wiley +1 more source
Pacing and Clinical Electrophysiology, Volume 49, Issue 5, Page 636-643, May 2026.ABSTRACT Background Procedural and clinical outcomes in patients with obesity undergoing catheter ablation for atrial fibrillation (AF) have been mixed. Clinical data in the context of pulsed field ablation (PFA) are currently limited in this patient cohort.
Francis J. Ha +6 more
wiley +1 more source
Technical Feasibility of the RHYTHMIA Mapping System in Pediatric Patients Weighing Less Than 20Kg
Pacing and Clinical Electrophysiology, Volume 49, Issue 5, Page 523-530, May 2026.ABSTRACT Background Catheter ablation in pediatric patients remains technically challenging. The RHYTHMIA high‐density mapping system is increasingly used in pediatric electrophysiology; however, procedural experience in patients weighing less than 20 kg is limited.
Wataru Sasaki +12 more
wiley +1 more source
Antiarrhythmic therapy and ECG [PDF]
British Journal of Anaesthesia, 2006 W.S. Brown, G Kessell
openaire +1 more source
Noninvasive cardiac radiation for ablation of ventricular tachycardia [PDF]
, 2017 Cooper, Daniel +12 more
core +2 more sources
Structure mirroring function: What's the ‘matter’ with the funny current?
The Journal of Physiology, Volume 604, Issue 9, Page 3513-3532, 1 May 2026.Abstract figure legend The ‘funny’ (If) current of cardiac pacemaker cells has been first identified in the late 1970s as a major mechanism in the generation and control of cardiac pacemaking. Decades of studies have since described the properties of the funny current and of its molecular components, HCN channels, in the heart and brain, providing the ...
Andrea Saponaro, Dario DiFrancesco
wiley +1 more source
2019 HRS/EHRA/APHRS/LAHRS expert consensus statement on catheter ablation of ventricular arrhythmias [PDF]
, 2019 Cuculich, Phillip, et al,
core +1 more source