Resistance of Gram-Negative Bacteria to Current Antibacterial Agents and Approaches to Resolve It
Antimicrobial resistance represents an enormous global health crisis and one of the most serious threats humans face today. Some bacterial strains have acquired resistance to nearly all antibiotics.
Zeinab Breijyeh+2 more
semanticscholar +1 more source
An improved dental composite with potent antibacterial function [PDF]
A new BisGMA-based antibacterial dental composite has been formulated and evaluated. Compressive strength and bacterial viability were utilized to evaluate the formed composites.
Almousa, Rashed+3 more
core +1 more source
Detection of bacterial sulfatase activity through liquid- and solid-phase colony-based assays
Bacterial arylsulfatases are crucial to biosynthesis in many microorganisms, as bacteria often utilize aryl sulfates as a source of sulfur. The bacterial sulfatases are associated with pathogenesis and are applied in many areas such as industry and ...
Hey Young Yoon+3 more
doaj +1 more source
Klebsiella pneumoniae poses a critical challenge to clinical and public health. Along with conjugative plasmids, nonconjugative resistance or virulence plasmids associated with carbapenem-resistant K. pneumoniae (CRKP), hypervirulent K. pneumoniae (hvKP),
Xiaoli Wang+10 more
doaj +1 more source
Facilitators and barriers to the successful implementation of pediatric antibacterial drug trials: Findings from CTTI's survey of investigators. [PDF]
An urgent need exists to develop new antibacterial drugs for children. We conducted research with investigators of pediatric antibacterial drug trials to identify facilitators and barriers in the conduct of these trials.
Benjamin, Daniel K+8 more
core +2 more sources
Antibiotic resistance is one of the biggest public health problems of our time. The nanoparticles are a powerful alternative to these antibiotics. Engineered nanoparticles show toxic effects on bacteria by different mechanisms.
Yeşim Dağlıoğlu+4 more
doaj +1 more source
Multifunctional antibiotic- and zinc-containing mesoporous bioactive glass scaffolds to fight bone infection [PDF]
Bone regeneration is a clinical challenge that requires multiple approaches. Sometimes, it also includes the development of new osteogenic and antibacterial biomaterials to treat the occurrence of possible infection processes derived from surgery. This study evaluates the antibacterial properties of meso-macroporous scaffolds coated with gelatin and ...
arxiv +1 more source
Antioxidant Capacity and Antimicrobial Activity of Commercial Samples of Guava Leaves (\u3cem\u3ePsidium guajava\u3c/em\u3e) [PDF]
Psidium guajava is a small tree native to South and Central America. Guava leaves have traditionally been used for treating different illnesses. These benefits can be attributed to phenolics and flavonoids produced by guava.
Alsaidi, Sahar+11 more
core +2 more sources
Do CVD grown graphene films have antibacterial activity on metallic substrates? [PDF]
Accurate assessment of the antibacterial activity of graphene requires consideration of both the graphene fabrication method and, for supported films, the properties of the substrate. Large-area graphene films produced by chemical vapor deposition were grown directly on copper substrates or transferred on a gold substrate and their effect on the ...
arxiv +1 more source
Metal nanoparticles: understanding the mechanisms behind antibacterial activity
As the field of nanomedicine emerges, there is a lag in research surrounding the topic of nanoparticle (NP) toxicity, particularly concerned with mechanisms of action. The continuous emergence of bacterial resistance has challenged the research community
Y. Slavin+3 more
semanticscholar +1 more source