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Multifunctional PdH-hydride MOFs for synergistic hydrogen and photothermal antibacterial therapy in accelerated wound healing [PDF]

Frontiers in Pharmacology
IntroductionThe growing threat of bacterial infections poses a critical challenge to public health, underscoring the urgent need for innovative antibacterial agents and therapeutic strategies. In response, we have developed a multifunctional nanoplatform
Qing Wang, Daixing Zhang, Yining Qi, Changbao Huang, Dejun Ding, Chuanliang Liu, Chuanliang Liu   +6 more
doaj   +2 more sources

Metallo‐supramolecular nanofibers based on type‐I photosensitizer for synergistic antibacterial therapy [PDF]

Smart Molecules
Photodynamic therapy (PDT) has shown great merits in treating microbial infections due to its absence of bacterial resistance. However, the pronounced hypoxic microenvironment in the bacterial infections limits the therapeutic efficiency of traditional ...
Shibo Lyu, Lukun Li, Jingdong Gao, Dapeng Liu, Fengling Song   +4 more
doaj   +2 more sources

Protein-Based Systems for Topical Antibacterial Therapy

Frontiers in Medical Technology, 2021
Recently, proteins are gaining attention as potential materials for antibacterial therapy. Proteins possess beneficial properties such as biocompatibility, biodegradability, low immunogenic response, ability to control drug release, and can act as ...
Raj Kumar Thapa, Krister Gjestvang Grønlien, Hanne Hjorth Tønnesen   +2 more
doaj   +1 more source

A multicenter evaluation of antibacterial use in hospitalized patients through the SARS-Cov-2 pandemic waves

BMC Infectious Diseases, 2023
Background Excessive use of antibiotics has been reported during the SARS-CoV-2 pandemic. We evaluated trends in antibiotic use and culture positive Gram-negative (GN)/Gram-positive (GP) pathogens in US hospitalized patients before and during the SARS ...
Laura A. Puzniak, Karri A. Bauer, Kalvin C. Yu, Janet A. Watts, ChinEn Ai, Vikas Gupta   +5 more
doaj   +1 more source

Antibacterial therapy of sepsis in extracorporeal detoxication: current problems and ways to solve them

Вестник анестезиологии и реаниматологии, 2020
The effectiveness of antibacterial therapy is a critical factor to improve treatment outcomes in sepsis patients. Impaired renal function and renal replacement therapy lead to a significant change in the pharmacokinetic parameters of most intravenous ...
A. V. Marukhov, M. V. Zakharov, N. V. Chubchenko, A. N. Belskikh, L. V. Buryakova, D. Yu. Lazarenko   +5 more
doaj   +1 more source

Guidelines of the Association of Anesthesiologists-Intensivists, the Interregional Non-Governmental Organization Alliance of Clinical Chemotherapists and Microbiologists, the Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy (IACMAC), and NGO Russian Sepsis Forum "Diagnostics and antimicrobial therapy of the infections caused by multiresistant microorganisms" (update 2022)

Вестник анестезиологии и реаниматологии, 2022
Strains of microorganisms characterized by resistance to antimicrobial drugs used in medical organizations continue to spread In most regions of the world including Russia.
V. B. Beloborodov, O. V. Goloschapov, V. G. Gusarov, А. V. Dekhnich, M. N. Zamyatin, N. A. Zubareva, S. K. Zyryanov, D. A. Kamyshova, N. N. Klimko, R. S. Kozlov, V. V. Kulabukhov, M. A. Petrushin, Yu. S. Polushin, D. A. Popov, V. A. Rudnov, S. V. Sidorenko, D. V. Sokolov, I. V. Shlyk, M. V. Edelshtein, S. V. Yakovlev   +19 more
doaj   +1 more source

Urinary tract infections in pregnancy (review)

Сибирский научный медицинский журнал, 2020
Urinary tract infections in pregnancy are common in obstetric practice. This urological pathology is recorded in about every third pregnant woman. There is no trend forward to decline the disease prevalence.
N. K. Nikiforovsky, E. A. Stepankova, A. O. Suhorukova   +2 more
doaj   +1 more source

SOME ASPECTS OF THERAPY OF BACTERIAL INFECTIONS OF UPPER RESPIRATORY TRACT: WHAT REMAINS BEYOND CLINICAL GUIDELINES?

Медицинский совет, 2017
Тhe article is devoted to discussion of use of rational antibacterial therapy of diseases of ENTorgans. The start of antibacterial therapy is a key to success of efficiency of treatment, leads to an eradication of bacteria and decrease of risk of chronic
N. G. Berdnikova, O. Y. Klimova, D. V. Tsyganko, V. A. Ekaterinchev   +3 more
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Effectiveness and safety of «Nifuroxazide-ECO» in therapy of escherichioses in children

Журнал инфектологии, 2021
In conditions of increasing antibiotic resistance and widespread antibiotic-associated diarrhea caused by Clostridium difficile, it is necessary to choose a rational drug for the empirical treatment of escherichioses, which has a wide range of ...
N. V. Gonchar, S. G. Mardanly, K. D. Ermolenko, I. V. Razd’yakonova, T. A. Koroleva, E. A. Martens, V. S. Kovalev, A. E. Maklakova   +7 more
doaj   +1 more source

Outpatient Management of Acute Respiratory Infections in Children

Педиатрическая фармакология, 2021
Background. Antimicrobial resistance is one of the most crucial problems in human health care worldwide. The main cause of this crisis is the excessive and misuse of antibacterial drugs (ADs).
Radima A. Mukozheva, Tatyana V. Kulichenko, Tatyana V. Vilchanskaya, Mariya A. Lazareva, Olga V. Romanova, Juliya S. Lashkova, Inga V. Artemova   +6 more
doaj   +1 more source