Results 1 to 10 of about 1,022,019 (313)

Evaluation of Dilution Susceptibility Testing Methods for Aztreonam in Combination with Avibactam against Enterobacterales

Microbiology Spectrum, 2022
As multidrug and pan-resistance among Enterobacterales continue to increase, there is an urgent need for more therapeutic options to treat these infections.
C. J. Kelley, A. Kennedy-Mendez, O. N. Walser, M. T. Thwaites, F. F. Arhin, C. M. Pillar, D. A. Hufnagel   +6 more
doaj   +1 more source

A standardized nomenclature for resistance-modifying agents in the Comprehensive Antibiotic Resistance Database

Microbiology Spectrum, 2023
Resistance-modifying agents have been historically underrepresented in the Comprehensive Antibiotic Resistance Database (CARD). In the process of curating over 60 new molecules into CARD’s Antibiotic Resistance Ontology, the limitations of current ...
Keaton W. Smith, Brian P. Alcock, Shawn French, Maya A. Farha, Amogelang R. Raphenya, Eric D. Brown, Andrew G. McArthur   +6 more
doaj   +1 more source

Effect of temperature on Escherichia coli bloodstream infection in a nationwide population-based study of incidence and resistance

Antimicrobial Resistance and Infection Control, 2022
Background The incidence of Escherichia coli bloodstream infections (BSI) is high and increasing. We aimed to describe the effect of season and temperature on the incidence of E. coli BSI and antibiotic-resistant E.
Sarah F. Feldman, Elizabeth Temkin, Liat Wulffhart, Amir Nutman, Vered Schechner, Pnina Shitrit, Racheli Shvartz, Mitchell J. Schwaber, Yehuda Carmeli   +8 more
doaj   +1 more source

Discovery of a novel integron-borne aminoglycoside resistance gene present in clinical pathogens by screening environmental bacterial communities

Microbiome, 2020
Background New antibiotic resistance determinants are generally discovered too late, long after they have irreversibly emerged in pathogens and spread widely.
Maria-Elisabeth Böhm, Mohammad Razavi, Nachiket P. Marathe, Carl-Fredrik Flach, D. G. Joakim Larsson   +4 more
doaj   +1 more source

A framework for identifying the recent origins of mobile antibiotic resistance genes

Communications Biology, 2021
Ebmeyer and colleagues developed a genomic framework for identification and scrutiny of the origins of antibiotic resistance genes. Using data scoured from the literature and publicly available genomes, their results indicate that only 81% of previously ...
Stefan Ebmeyer, Erik Kristiansson, D. G. Joakim Larsson   +2 more
doaj   +1 more source

Metagenomics and antibiotics [PDF]

Clinical Microbiology and Infection, 2012
Most of the bacterial species that form part of the biosphere have never been cultivated. In this situation, a comprehensive study of bacterial communities requires the utilization of non-culture-based methods, which have been named metagenomics.
María Blanca Sánchez, José L. Martínez, Leonor Garmendia, Alvaro Hernández   +3 more
openaire   +2 more sources

Pharmacogenomics of Antibiotics [PDF]

International Journal of Molecular Sciences, 2020
Although the introduction of antibiotics in medicine has resulted in one of the most successful events and in a major breakthrough to reduce morbidity and mortality caused by infectious disease, response to these agents is not always predictable, leading to differences in their efficacy, and sometimes to the occurrence of adverse effects.
Stocco G., Lucafo M., Decorti G.
openaire   +5 more sources

Perioperative Antibiotics [PDF]

The Journal of Arthroplasty, 2014
infection, arthroplasty ...
Hansen, Erik, Belden, Katherine, Silibovsky, Randi, Vogt, Markus, Arnold, William, Bicanic, Goran, BINI, STEFANO, CATANI, Fabio, Chen, Jiying, Ghazavi, Mohammad, Godefroy, Karine M., Holham, Paul, Hosseinzadeh, Hamid, Kim II, Kang, Kirketerp Moøller, Klaus, Lidgren, Lars, Lin, Jian Hao, Lonner, Jess H., Moore, Christopher C., Papagelopoulos, Panayiotis, Poultsides, Lazaros, Randall, R. Lor, Roslund, Brian, Saleh, Khalid, Salmon, Julia V., Schwarz, Edward, Stuyck, Jose, Dahl, Annette W, Yamada, Koji   +28 more
openaire   +8 more sources

Mobile resistome of human gut and pathogen drives anthropogenic bloom of antibiotic resistance

Microbiome, 2020
Background The impact of human activities on the environmental resistome has been documented in many studies, but there remains the controversial question of whether the increased antibiotic resistance observed in anthropogenically impacted environments ...
Kihyun Lee, Dae-Wi Kim, Do-Hoon Lee, Yong-Seok Kim, Ji-Hye Bu, Ju-Hee Cha, Cung Nawl Thawng, Eun-Mi Hwang, Hoon Je Seong, Woo Jun Sul, Elizabeth M. H. Wellington, Christopher Quince, Chang-Jun Cha   +12 more
doaj   +1 more source

A Novel, Integron-Regulated, Class C β-Lactamase

Antibiotics, 2020
AmpC-type β-lactamases severely impair treatment of many bacterial infections, due to their broad spectrum (they hydrolyze virtually all β-lactams, except fourth-generation cephalosporins and carbapenems) and the increasing incidence of plasmid-
Maria-Elisabeth Böhm, Mohammad Razavi, Carl-Fredrik Flach, D. G. Joakim Larsson   +3 more
doaj   +1 more source