Results 61 to 70 of about 107,637 (299)

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source

Probiotics for the Prevention of Pediatric Antibiotic-Associated Diarrhea [PDF]

EXPLORE, 2016
Goldenberg JZ, Lytvyn L, Steurich J, Parkin P, Mahant S, Johnston BC. Probiotics for the prevention of pediatric antibiotic-associated diarrhea.Cochrane Database Syst Rev2015, Issue 12. Art. No.: CD004827. http://dx.doi.org/10.1002/14651858.CD004827.pub4.Antibiotics are frequently prescribed in children.
Shelby R, Hayes, Ashley J, Vargas
openaire   +2 more sources

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

The fecal microbiome in dogs with acute diarrhea and idiopathic inflammatory bowel disease. [PDF]

, 2012
Recent molecular studies have revealed a highly complex bacterial assembly in the canine intestinal tract. There is mounting evidence that microbes play an important role in the pathogenesis of acute and chronic enteropathies of dogs, including ...
Cook, Audrey K., Dillman, Enricka M., Dowd, Scot E., García Mazcorro, José Francisco, Heilmann, Romy M., Heimesaat, Markus M., Ivanov, Ivan, Kachroo, Priyanka, Markel, Melissa, Minamoto, Yasushi, Steiner, Jörg M., Suchodolski, Jan S., Toresson, Linda, Unterer, Stefan   +13 more
core   +5 more sources

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

Advanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng, Kaiwen Chen, Qiwei Ying, Shuya Wang, Xin Li, Guanlin Li, Yantao Zhao, Binghua Ma, Huanan Wang, Dawei Li, Lijun Zhang, Jian Zhang, Yu Zhao, Changle Ren, Baodong Chen, Yueming Song   +15 more
wiley   +1 more source

Lauric acid is an inhibitor of Clostridium difficile growth in vitro and reduces inflammation in a mouse infection model [PDF]

, 2018
Indexación: Scopus.Clostridium difficile is a Gram-positive, spore-forming anaerobic human gastrointestinal pathogen. C. difficile infection (CDI) is a major health concern worldwide, with symptoms ranging from diarrhea to pseudomembranous colitis, toxic
Ababouch, Abt, Ananthakrishnan, Barbour, Bartolotta, Bergsson, Bhattacharjee, Buckley, Burke, Carpo, Chen, Clark, Croasdell, Crowther, Dapa, Dapa, Dayrit, de Roos, Deakin, Deng, Desai, Edwards, Ekanayaka, Eyres, Ferreyra, Fischer, Francis, Galbraith, German, Harnvoravongchai, Hinton, Huang, Hung, Hung, Immanuel, Johnson, Kabara, Katan, Kim, Kint, Kitahara, Kliewer, Liu, Louie, Lynch, Martin, Martin, May, McDonald, McEllistrem, Miller, Nakatsuji, Namkung, Nobmann, Pettit, Pizarro-Guajardo, Pruitt, Rodriguez-Palacios, Rouse, Ruhr, Ruzin, Shearer, Shilling, Smits, Sorg, Surawicz, Theinsathid, Thompson, Vardakas, Villafuerte Galvez, Wilcox, Yonezawa   +71 more
core   +1 more source

Ultrasound‐Activated Bifunctional Piezoelectric Hydrogel Dressings Promote Infected Wound Healing via Regulating Angiogenesis and Lymphangiogenesis

Advanced Science, EarlyView.
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li, Zhen Ding, Zhihua Liu, Hao Chen, Jianyang Shan, Yanxuan Shao, Yaling Yu, Gen Wen   +7 more
wiley   +1 more source

Systematic review of antimicrobial drug prescribing in hospitals. [PDF]

, 2006
Prudent antibiotic prescribing to hospital inpatients has the potential to reduce the incidences of antimicrobial resistance and healthcare-associated infection.
Brown, E, Davey, P, Fenelon, L, Finch, R, Gould, I.M., Homes, A, Ramsay, Craig R, Taylor, E, Wiffen, P, Wilcox, M   +9 more
core   +3 more sources

The Spectrum of Pseudomembranous Enterocolitis and Antibiotic-Associated Diarrhea [PDF]

Archives of Internal Medicine, 2002
Pseudomembranous (entero)colitis is primarily caused by Clostridium difficile infection. The most common predisposing factor is prior use of antibiotics, including vancomycin and metronidazole, which themselves are therapy for C difficile colitis. Other risk factors have also been described.
Brian W, Hurley, Cuong C, Nguyen
openaire   +2 more sources

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

Advanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng, Qipeng Cheng, Xiaoxu Zhang, Honglan Wang, Jinghan Zhang, Xinyi Ding, Pengfei Zhang, Lanhua Yi, Kwok‐Yin Wong, Kin‐Fai Chan, Sheng Chen, Sharon Shui Yee Leung   +11 more
wiley   +1 more source