Results 61 to 70 of about 8,328,368 (232)

Harmonizing Rigidity and Flexibility: Embedding COF Quantum Dots Into Extracellular Matrix Gel as Carbon Monoxide Depot for Acoustically Triggered Time‐Programmable Anti‐Infective Therapy

Advanced Science, EarlyView.
A rigid‑flexible integrated CO depot is engineered by embedding rigid COFQDs into a flexible ECM gel network. The rigid framework enables high‑capacity CO storage and sonodynamic bacterial killing, while the flexible ECM gel controls sustained CO release, collectively eradicating multidrug‑resistant infection and promoting scarless healing.
Baohong Sun, Fang Han, Chunxiao Zhu, Zhiyuan Yang, Haoru Wang, Jinpei Mei, Jie Chen, Jingwen Zhu, Zihan Bo, Taju Wu, Xiaogang Zhou, Tao Ma, Yutian Su, Youhui Lin   +13 more
wiley   +1 more source

Antibiotic-associated diarrhea [PDF]

DMW - Deutsche Medizinische Wochenschrift, 2004
E C, Reisinger, M, Lademann, R, Krause
openaire   +3 more sources

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

The association between histamine 2 receptor antagonist use and Clostridium difficile infection: a systematic review and meta-analysis. [PDF]

, 2013
Background Clostridium difficile infection (CDI) is a major health problem. Epidemiological evidence suggests that there is an association between acid suppression therapy and development of CDI.
Sutton, AJ, Aref A. Bin. Abdulhak, Abdulhak Aref A. Bin., Hernandez, Adrian V., Imad M. Tleyjeh (104252), AlGhamdi, Mushabab, Alex J Sutton, Patricia J. Erwin, Muhammad Riaz (104236), Erwin, Patricia J., Mushabab AlGhamdi (112556), Baddour, LM, Alasmari Faisal A., Baddour, Larry M., Alasmari, Faisal A., Sutton, Alex J., Faisal A. Alasmari, Alasmari, FA, Faisal A. Alasmari (112549), F. A. Alasmari (7656575), A. R. Khan (3951662), Mushabab Alghamdi, AlGhamdi Mushabab, Alex J. Sutton, Khan, AR, Aref A. Bin. Abdulhak (385158), Tleyjeh, IM, I. M. Tleyjeh (7656566), Alex J. Sutton (112577), Garbati Musa A., L. M. Baddour (7656596), M. A. Garbati (7656578), Imad M. Tleyjeh, M. Alghamdi (7687019), Imad M Tleyjeh, Khan Abdur Rahman, Al-Tannir, M, Patricia J Erwin, Muhammad Riaz, Abdur Rahman Khan (104234), Tleyjeh, Imad M., Garbati, MA, Aref Bin Abdulhak, A. B. Abdulhak (7687013), Erwin, PJ, Sutton Alex J., M. Riaz (7656572), Garbati, Musa A., Riaz Muhammad, Abdulhak, Aref A. Bin., Musa A Garbati, M. Al-Tannir (7687016), Mohamad Al-Tannir, Patricia J. Erwin (104246), Abdur Rahman Khan, Al-Tannir Mohamad, A. J. Sutton (7648487), Alghamdi, M, Faisal A Alasmari, Musa A. Garbati, Erwin Patricia J., Larry M Baddour, Baddour Larry M., P. J. Erwin (7656587), Abdulhak, AB, Larry M. Baddour (104249), Riaz, Muhammad, Riaz, M, Khan, Abdur Rahman, Al-Tannir, Mohamad, Tleyjeh Imad M., Mohamad Al-Tannir (385159), Musa A. Garbati (104244), Larry M. Baddour   +73 more
core   +1 more source

Overcoming Transmission Barriers: A Dual‐Functional Adhesive Hydrogel for Direct Monkeypox Virus Neutralization and Wound Healing

Advanced Science, EarlyView.
MPXV infection leads to persistent viral replication and severe local inflammation, while existing treatments cannot simultaneously remove viruses and repair injured tissue. This study constructs Polymer@mPDA@Gel hydrogel via a two‐step hierarchical assembly method: mPDA anchors photothermal polymers to form antiviral photothermal subunits, which are ...
Ming Zhang, Jiaxin Tian, Xiaolong Zhu, Xiao Li, Xiangshu Qiu, Yuanyuan Li, Ben Zhong Tang, Ning Shi   +7 more
wiley   +1 more source

Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice. [PDF]

, 2012
Relapsing C. difficile disease in humans is linked to a pathological imbalance within the intestinal microbiota, termed dysbiosis, which remains poorly understood. We show that mice infected with epidemic C.
Parkhill Julian, Duncan Sylvia H., Deakin, Laura J., Thomas R. Connor (125272), Schreiber Fernanda, Brandt, Cordelia, Pickard Derek J., Flint, Harry J, Harry J. Flint (125298), Parkhill, J, Flint, Harry James, Trevor D. Lawley (125265), Simon Clare, Roland Rad (125284), David Goulding (125280), Julian Parkhill (30393), Claire Raisen (125275), Schreiber, F, Clare Simon, Taane G Clark, Deakin Laura J., Connor Thomas R., Taane G. Clark (106263), Clark, Taane G., Gordon Dougan, Duncan, SH, Sylvia H. Duncan (125296), Stares, Mark D., Raisen Claire, Roland Rad, Trevor D Lawley, Rad, Roland, Derek J. Pickard (125293), Sylvia H Duncan, Walker Alan W., Harry J Flint, Goulding David, Rad, R, Derek J Pickard, Deakin, LJ, Schreiber, Fernanda, Clark, Taane G, Clark, TG, Rad Roland, Walker, Alan W, Flint Harry J., Goulding, David, Alan W. Walker (50247), Raisen, C, Stares, MD, Pickard, Derek J, Flint, Harry J., Lawley, Trevor D, Deakin, Laura J, Connor, Thomas R, Claire Raisen, Brandt, C, Walker, AW, Mark D Stares, Walker, Alan W., Duncan, Sylvia H, Dougan Gordon, Connor, Thomas Richard, Clare, Simon, Pickard, Derek J., Laura J Deakin, Fernanda Schreiber, Fernanda Schreiber (85280), Lawley, TD, Clare, S, Julian Parkhill, Alan W Walker, David Goulding, Lawley, Trevor D., Raisen, Claire, Mark D. Stares (125271), Cordelia Brandt (125287), Laura J. Deakin (125290), Brandt Cordelia, Dougan, Gordon, Pickard, DJ, Duncan, Sylvia H., Parkhill, Julian, Simon Clare (125268), Clark Taane G., Flint, HJ, Gordon Dougan (30395), Thomas R Connor, Stares Mark D., Stares, Mark D, Goulding, D, Cordelia Brandt, Connor, TR, Dougan, G, Lawley Trevor D.   +94 more
core   +1 more source

Probiotics for the Prevention of Pediatric Antibiotic-Associated Diarrhea [PDF]

EXPLORE, 2016
Goldenberg JZ, Lytvyn L, Steurich J, Parkin P, Mahant S, Johnston BC. Probiotics for the prevention of pediatric antibiotic-associated diarrhea.Cochrane Database Syst Rev2015, Issue 12. Art. No.: CD004827. http://dx.doi.org/10.1002/14651858.CD004827.pub4.Antibiotics are frequently prescribed in children.
Shelby R, Hayes, Ashley J, Vargas
openaire   +2 more sources

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

Advanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang, Yishu Zhang, Sijia Feng, Xiaoqing Ma, Jiayi Feng, Junwei Wang, Jialin Gao, An Pan, Dapeng Wu, Kang Ding, Caijuan Zheng, Qi Lv, Lihong Hu   +12 more
wiley   +1 more source

Characterization of Diarrheagenic Enteroaggregative Escherichia coli in Danish Adults—Antibiotic Treatment Does Not Reduce Duration of Diarrhea

Frontiers in Cellular and Infection Microbiology, 2018
Enteroaggregative Escherichia coli (EAEC) is frequently isolated from sporadic cases of diarrhea and in outbreaks of gastroenteritis in several regions of the world.
Betina Hebbelstrup Jensen, Betina Hebbelstrup Jensen, Camilla Adler Sørensen, Stig Hebbelstrup Rye Rasmussen, Dorthe Rejkjær Holm, Alice Friis-Møller, Jørgen Engberg, Hengameh C. Mirsepasi-Lauridsen, Carsten Struve, Anette M. Hammerum, Lone Jannok Porsbo, Randi Føns Petersen, Andreas Munk Petersen, Andreas Munk Petersen, Karen Angeliki Krogfelt   +14 more
doaj   +1 more source

Dual‐Responsive Hydrogels Integrate Bioelectrical Stimulation and Piezo‐Photocatalysis for Regenerative Treatment of Infected Wounds

Advanced Science, EarlyView.
A wireless, dual‐responsive hydrogel (PVA/(PVDF‐TrFE)/BiOClBr@PDA) is developed to promote efficient regeneration of infected wounds by integrating piezoelectric stimulation with piezo‐photocatalytic pathways. Under simultaneous light and ultrasonic stimulation, the hydrogel generates therapeutic electrical cues and reactive oxygen species, disrupting ...
Baoying Dai, Wenxuan Qie, Xiaoye Li, Jingben Zheng, Ao He, Heng Dong, Jiangjiang Yan, Hao Zhang, Ziheng Pan, Hang Yin, Chuyi Zhou, Rui Kong, Hao Wang, Binghan Dai, Yannan Xie, Zhiqun Lin   +15 more
wiley   +1 more source