Porcine proliferative enteropathy: overview of disease dynamics and non-antibiotic alternatives for prevention and control strategies. [PDF]
Gómez-Osorio LM +6 more
europepmc +1 more source
AM symbiosis induces GhWAK13 to promote fungal colonization. GhNTF3 negatively regulates symbiosis by promoting SA biosynthesis. GhWAK13 sequesters GhNTF3 at the membrane, limiting its nuclear translocation and relieving SA‐mediated suppression. Under Verticillium stress, GhNTF3 enters the nucleus and interacts with GhJAZ6 to activate SA signaling ...
Shuangjie Jia +10 more
wiley +1 more source
A Comparative Study of Formic Acid, Herbal Mixture and Spirulina Powder as Antibiotic Alternatives in Broiler Diets: Effects on Growth, Carcass Traits, Blood Biochemistry and Microbial Load. [PDF]
Ashour EA +7 more
europepmc +1 more source
ALTERNATIVE TO ANTIBIOTICS - PREPARATION FOR POST ANTIBIOTIC ERA
Emergence of resistance against antibiotics is perhaps leading towards a stage of total ineffectiveness of these medicines as some tools to protect lives from infection of pathogenic micro organisms. The research communities are trying in various ways to find out means and tools to overcome such possible situation.
openaire +1 more source
One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong +11 more
wiley +1 more source
Antibiotic Alternatives and Next-Generation Therapeutics for <i>Salmonella</i> Control: A One Health Approach to Combating Antimicrobial Resistance. [PDF]
Saleh M, Verma A, Shaaban KA, Helmy YA.
europepmc +1 more source
A Synthetic Platform for Antibody Junctional Diversification Beyond Natural Constraints
ARESEC is a synthetic platform that reconstructs functional V(D)J recombination in HEK293T cells. By introducing RSS elements and co‐expressing RAG1/2 and TdT across all three antibody CDRs, it enables programmable junctional diversification and direct generation of high‐affinity variants targeting PD‐1/PD‐L1, overcoming the evolutionary constraints of
Wang Liu +3 more
wiley +1 more source
<i>In vitro</i> inhibitory effects of gentamicin and ceftiofur against <i>Trypanosoma evansi</i>: Promising antibiotic alternatives for equine trypanosomosis in Thailand. [PDF]
Rudeekiatthamrong A +2 more
europepmc +1 more source
Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy
Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song +7 more
wiley +1 more source

