Results 101 to 110 of about 1,093,095 (408)
Abstract Pelvic organ prolapse (POP) affects many women, with an estimated lifetime risk of surgical intervention of 18.7%. There is a need for alternative approaches as the use of synthetic nondegradable mesh was stopped due to severe adverse events, and as current methods for pelvic floor repair have high POP recurrence rates.
Sofie Husted Laursen+6 more
wiley +1 more source
Bacterial fitness shapes the population dynamics of antibiotic-resistant and -susceptible bacteria in a model of combined antibiotic and anti-virulence treatment [PDF]
Bacterial resistance to antibiotic treatment is a huge concern: introduction of any new antibiotic is shortly followed by the emergence of resistant bacterial isolates in the clinic. This issue is compounded by a severe lack of new antibiotics reaching the market.
arxiv
The aim of the study was to assess the effect of timing of preoperative surgical antibiotic prophylaxis (SAP) on surgical site infection (SSI) and compare the different timing intervals.
S. D. de Jonge+5 more
semanticscholar +1 more source
Antibiotic prophylaxis in cataract surgery – An evidence-based approach
Various protocols are being followed for endophthalmitis prophylaxis in cataract surgery, and this subject continues to be a matter of debate. We summarize the most recent evidence-based studies on this topic with additional stress on intracameral (IC ...
Aravind Haripriya
doaj +1 more source
This retrospective study investigated risk factors for surgical site infections (SSIs) in right‐sided colon cancer surgeries using intracorporeal anastomosis (IA). The results demonstrated that preoperative oral antibiotics (OA) significantly reduced SSI rates, with OA identified as an independent protective factor, suggesting its beneficial role in ...
Naoya Ozawa+8 more
wiley +1 more source
Adherence to guidelines for surgical antibiotic prophylaxis: a review
Context and objectives: The appropriate use of antibiotic prophylaxis in the perioperative period may reduce the rate of infection in the surgical site.
Marise Gouvêa+3 more
doaj
Making SMART decisions in prophylaxis and treatment studies [PDF]
The optimal prophylaxis, and treatment if the prophylaxis fails, for a disease may be best evaluated using a sequential multiple assignment randomised trial (SMART). A SMART is a multi-stage study that randomises a participant to an initial treatment, observes some response to that treatment and then, depending on their observed response, randomises ...
arxiv
Adherence to hospital’s guidelines [PDF]
This study was designed to assess the compliance to local hospital guidelines for antimicrobial prophylaxis in general surgery in terms of the appropriateness of prophylactic antibiotic indication, the choice of antibiotic, the dose administered, the ...
Bonello, Daniela, Stafrace, Yanika
core
Extended Prophylactic Antibiotics for Mastectomy with Immediate Breast Reconstruction: A Meta-analysis [PDF]
Background: The risk of surgical site infection (SSI) for breast surgery in patients without additional risk factors is low, below 5%. Evidence shows the risk of SSI is significantly elevated in patients undergoing immediate breast reconstruction (IBR ...
Chong, Weelic, Hai, Yang, Lazar, Melissa
core +1 more source
From the microbiome to the central nervous system, an update on the epidemiology and pathogenesis of bacterial meningitis in childhood [version 1; referees: 3 approved] [PDF]
In the past century, advances in antibiotics and vaccination have dramatically altered the incidence and clinical outcomes of bacterial meningitis. We review the shifting epidemiology of meningitis in children, including after the implementation of ...
Janowski, Andrew B, Newland, Jason G
core +3 more sources