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Dental Clinics of North America, 2003
Through billions of years of evolution, microbes have developed myriad defense mechanisms designed to ensure their survival. This protection is readily transferred to their fellow life forms via transposable elements. Despite very early warnings, humans have chosen to abuse the gift of antibiotics and have created a situation where all microorganisms ...
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Through billions of years of evolution, microbes have developed myriad defense mechanisms designed to ensure their survival. This protection is readily transferred to their fellow life forms via transposable elements. Despite very early warnings, humans have chosen to abuse the gift of antibiotics and have created a situation where all microorganisms ...
openaire +2 more sources
Glycopeptide Antibiotic Resistance
Annual Review of Pharmacology and Toxicology, 2002Glycopeptide antibiotics are integral components of the current antibiotic arsenal that is under strong pressures as a result of the emergence of a variety of resistance mechanisms over the past 15 years. Resistance has manifested itself largely through the expression of genes that encode proteins that reprogram cell wall biosynthesis and thus evade ...
Jeff, Pootoolal +2 more
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Reversing antibiotic resistance
Expert Opinion on Investigational Drugs, 2002Over the past decade many well-tried chemotherapeutic agents have lost their effectiveness. This is due to a phenomenon referred to as multi-drug resistance. The most likely cause of multi-drug resistance is an increase in the activity of an efflux pump mediated through the actions of a P-glycoprotein.
Hodgkinson, Rebecca, Sharples, Derek
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How antibiotics cause antibiotic resistance
Drug Discovery Today, 1999Antimicrobial agents are approaching the end of their effectiveness. The prevailing drug development strategy is based on a presumption that results in resistance: that disease can be cured by exploitation of the vulnerabilities in microbial reproduction. Although some did predict the evolution of resistance to such drugs, the mechanisms by which genes
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Reconsidering Antibiotic Resistance
AJN, American Journal of Nursing, 2017What if our prescribing practices are wrong?
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Antibiotic-resistant enterococci
Journal of Hospital Infection, 1992Enterococci have emerged as an important cause of nosocomial infection. Successful antibiotic treatment of serious enterococcal infection usually depends on the synergistic bactericidal effect achieved by the combination of a cell wall-active agent, such as ampicillin or a glycopeptide, and an aminoglycoside.
J W, Gray, S J, Pedler
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International Journal of Medicine in Developing Countries, 2019
Antimicrobial resistance (AMR) is a universal public health problem affecting the benefit of antibiotics. Antibiotic use, inappropriate dosage, and genetics led to the spread of multidrug resistance among pathogenic bacteria, and it became hard to treat ...
Nuha Mobarki +2 more
semanticscholar +1 more source
Antimicrobial resistance (AMR) is a universal public health problem affecting the benefit of antibiotics. Antibiotic use, inappropriate dosage, and genetics led to the spread of multidrug resistance among pathogenic bacteria, and it became hard to treat ...
Nuha Mobarki +2 more
semanticscholar +1 more source
Minimising antibiotic resistance
The Lancet Infectious Diseases, 2005The problems associated with antibiotic resistance have led to several agency and governmental reports since 1998, along with many sets of usage guidelines. These documents stress the desirability of reducing antimicrobial prescribing, which has subsequently fallen in several countries, including the UK.
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Medical Journal of Australia, 2002
Antibiotic resistance is a consequence of antibiotic use - we need to use antibiotics less and to use them prudently. Plans to combat antibiotic resistance were recently proposed by the World Health Organization, a United States interagency taskforce and the Australian Joint Expert Technical Advisory Committee on Antibiotic Resistance.
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Antibiotic resistance is a consequence of antibiotic use - we need to use antibiotics less and to use them prudently. Plans to combat antibiotic resistance were recently proposed by the World Health Organization, a United States interagency taskforce and the Australian Joint Expert Technical Advisory Committee on Antibiotic Resistance.
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Antibiotic-resistant gonorrhoea
Hospital Medicine, 2000The gonococcus has become either relatively or completely resistant to many antibiotics. However, knowledge of prevailing local resistance patterns and region in the world of acquisition of infection means that effective treatment is always possible.
J S, Bingham, D, Barlow
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