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Antibiotic Resistance: One Health One World Outlook
Antibiotic resistance (ABR) is a growing public health concern worldwide, and it is now regarded as a critical One Health issue. One Health’s interconnected domains contribute to the emergence, evolution, and spread of antibiotic-resistant microorganisms
B. Aslam+11 more
semanticscholar +1 more source
Antibiotics are medicines used to prevent and treat bacterial infections. Antibiotic resistance occurs when the response of bacteria to medicines. Unfortunately nowadays the emergence of resistance among bacterial pathogens is a major public worldwide health problem.
openaire +4 more sources
Mechanisms of antibiotic resistance [PDF]
Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major ...
Lin, Jun+5 more
openaire +6 more sources
A Novel, Integron-Regulated, Class C β-Lactamase
AmpC-type β-lactamases severely impair treatment of many bacterial infections, due to their broad spectrum (they hydrolyze virtually all β-lactams, except fourth-generation cephalosporins and carbapenems) and the increasing incidence of plasmid-
Maria-Elisabeth Böhm+3 more
doaj +1 more source
CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database
The Comprehensive Antibiotic Resistance Database (CARD; https://card.mcmaster.ca) is a curated resource providing reference DNA and protein sequences, detection models and bioinformatics tools on the molecular basis of bacterial antimicrobial resistance (
Brian P. Alcock+33 more
semanticscholar +1 more source
Model Systems of Human Intestinal Flora, to Set Acceptable Daily Intakes of Antimicrobial Residues [PDF]
The veterinary use of antimicrobial drugs in food producing animals may result in residues in food, that might modify the consumer gut flora. This review compares three model systems that maintain a complex flora of human origin: (i) human flora ...
Cemiglia CE+9 more
core +2 more sources
The Association between Insertion Sequences and Antibiotic Resistance Genes
Insertion sequences (ISs) are abundant mobile genetic elements on bacterial genomes, responsible for mobilization of many genes, including antibiotic resistance genes (ARGs).
Mohammad Razavi+3 more
doaj +1 more source
Environmental adaptation of Listeria monocytogenes is a complex process involving various mechanisms that can contribute to their survival in the environment, further spreading throughout the food chain and the development of listeriosis. The aim of this
Tereza Gelbicova+8 more
doaj +1 more source
Colistin Dependency among Colistin-Heteroresistant Acinetobacter baumannii Isolates
Colistin dependent (CD) isolates are dependent on colistin for optimal growth. Here we aimed to systematically determine the emergence of CD among colistin-heteroresistant carbapenem-resistant Acinetobacter baumannii (CRAB) isolates. We also examined the
Hadas Kon+6 more
doaj +1 more source
Minimizing treatment-induced emergence of antibiotic resistance in bacterial infections
Treatment of bacterial infections currently focuses on choosing an antibiotic that matches a pathogen’s susceptibility, with less attention paid to the risk that even susceptibility-matched treatments can fail as a result of resistance emerging in ...
Mathew Stracy+14 more
semanticscholar +1 more source