Results 31 to 40 of about 4,451,314 (357)
Microbiome, 2019 Background Hospital wastewaters contain fecal material from a large number of individuals, of which many are undergoing antibiotic therapy. It is, thus, plausible that hospital wastewaters could provide opportunities to find novel carbapenemases and ...
Nachiket P. Marathe +7 more
doaj +1 more source
Microorganisms, 2021 Using whole-genome sequencing and cloning of the target gene, we identified blaOXA-900 carbapenemase, a novel blaOXA belonging to a distant and distinct sub-family of blaOXA-48-like. The plasmid-mediated gene was identified in a C.
Sammy Frenk +9 more
doaj +1 more source
Clinically relevant mutations in core metabolic genes confer antibiotic resistance
Science, 2021 The many roads to resistance Antibiotic resistance arising from mutation is common among pathogenic bacteria. However, this process is not well understood, and most of the mutations that have been identified to confer resistance do so by modification of ...
A. Lopatkin +9 more
semanticscholar +1 more source
Antibiotics, 2023 Beta-lactam resistance can lead to increased mortality, higher healthcare expenses, and limited therapeutic options. The primary mechanism of beta-lactam resistance is the production of extended-spectrum beta-lactamases (ESBL) and AmpC beta-lactamases ...
Hadas Kon +7 more
doaj +1 more source
Comparative transcriptomics of multidrug-resistant Acinetobacter baumannii in response to antibiotic treatments [PDF]
, 2018 Multidrug-resistant Acinetobacter baumannii, a major hospital-acquired pathogen, is a serious health threat and poses a great challenge to healthcare providers.
Chan, Ting-Fung +8 more
core +2 more sources
mBio, 2018 Antibiotic resistance is a growing crisis and a grave threat to human health. It is projected that antibiotic-resistant infections will lead to 10 million annual deaths worldwide by the year 2050.
Victor I. Band +5 more
doaj +1 more source
Two pandemics: the COVID-19 pandemic’s impact on future AMR collaboration in Europe
Humanities & Social Sciences Communications, 2023 Based on 117 responses to a web survey in 29 European countries and interviews with bureaucrats in managerial positions, this paper investigates how people working professionally with antimicrobial resistance (AMR) assess the impact of the COVID-19 ...
Elina Lampi +3 more
doaj +1 more source
CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database
Nucleic Acids Res., 2016 The Comprehensive Antibiotic Resistance Database (CARD; http://arpcard.mcmaster.ca) is a manually curated resource containing high quality reference data on the molecular basis of antimicrobial resistance (AMR), with an emphasis on the genes, proteins ...
Baofeng Jia +22 more
semanticscholar +1 more source
The Spread of Antibiotic Resistance Genes In Vivo Model
The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2022 Infections caused by antibiotic-resistant bacteria are a major public health threat. The emergence and spread of antibiotic resistance genes (ARGs) in the environment or clinical setting pose a serious threat to human and animal health worldwide ...
Shuan Tao +4 more
semanticscholar +1 more source
A degenerate PCR-based strategy as a means of identifying homologues of aminoglycoside and ß-lactam resistance genes in the gut microbiota [PDF]
, 2014 peer-reviewedBackground: The potential for the human gut microbiota to serve as a reservoir for antibiotic resistance genes has been the subject of recent discussion. However, this has yet to be investigated using a rapid PCR-based approach.
Cotter, Paul D. +4 more
core +1 more source