Results 31 to 40 of about 4,426,359 (306)

The expression of antibiotic resistance genes in antibiotic‐producing bacteria [PDF]

Molecular Microbiology, 2014
SummaryAntibiotic‐producing bacteria encode antibiotic resistance genes that protect them from the biologically active molecules that they produce. The expression of these genes needs to occur in a timely manner: either in advance of or concomitantly with biosynthesis. It appears that there have been at least two general solutions to this problem.
Stefanie, Mak, Ye, Xu, Justin R, Nodwell
openaire   +2 more sources

Towards an ecological approach to antibiotics and antibiotic resistance genes [PDF]

Clinical Microbiology and Infection, 2009
Antibiotics are likely the most important compounds used for human therapy. Conversely, antibiotic resistance is a relevant medical problem. However, besides their relevance for human health, antibiotics and their resistance genes are important elements that can influence the structure of microbial populations.
Fajardo, A., Linares, J.F., Martínez, J.L.   +2 more
openaire   +3 more sources

Comparison of Antibiotic Resistance Mechanisms in Antibiotic-Producing and Pathogenic Bacteria

Molecules, 2019
Antibiotic resistance poses a tremendous threat to human health. To overcome this problem, it is essential to know the mechanism of antibiotic resistance in antibiotic-producing and pathogenic bacteria. This paper deals with this problem from four points
Hiroshi Ogawara
doaj   +1 more source

Antibiotic Resistance in Aquatic Systems [PDF]

, 2017
Rivers, lakes and the ocean receive antibiotic resistance genes from human environments.
Pruden, Amy, Amy Pruden, Satoru Suzuki, Tong Zhang, Virta, Marko, Zhang, Tong, Suzuki, Satoru, Marko Virta   +7 more
core   +1 more source

Evolution by Pervasive Gene Fusion in Antibiotic Resistance and Antibiotic Synthesizing Genes [PDF]

Computation, 2015
Phylogenetic (tree-based) approaches to understanding evolutionary history are unable to incorporate convergent evolutionary events where two genes merge into one. In this study, as exemplars of what can be achieved when a tree is not assumed a priori, we have analysed the evolutionary histories of polyketide synthase genes and antibiotic resistance ...
Coleman, Orla, Hogan, Ruth, McGoldrick, Nicole, Rudden, Niamh, Mcinerney, James   +4 more
openaire   +2 more sources

Metagenomic Survey Reveals More Diverse and Abundant Antibiotic Resistance Genes in Municipal Wastewater Than Hospital Wastewater

Frontiers in Microbiology, 2021
Alongside antibiotic resistance, co-selection of antibiotics, biocides, and metal resistance is a growing concern. While hospital wastewater is considered a hotspot for antibiotic-resistant bacteria (ARB) and genes (ARGs), the scenario in India, one of ...
Dengwei Zhang, Dengwei Zhang, Ye Peng, Ye Peng, Chak-Lun Chan, Chak-Lun Chan, Hilda On, Hogan Kok-Fung Wai, Hogan Kok-Fung Wai, Sandeep Singh Shekhawat, Akhilendra Bhushan Gupta, Alok Kumar Varshney, Alok Kumar Varshney, Rungtip Chuanchuen, Xudong Zhou, Yankai Xia, Suisha Liang, Suisha Liang, Keiji Fukuda, Krishna Mohan Medicherla, Krishna Mohan Medicherla, Hein M. Tun, Hein M. Tun, Hein M. Tun   +23 more
doaj   +1 more source

Co‐localization of clinically relevant antibiotic‐ and heavy metal resistance genes on plasmids in Klebsiella pneumoniae from marine bivalves

MicrobiologyOpen, 2023
Klebsiella pneumoniae is an opportunistic pathogen frequently associated with antibiotic resistance and present in a wide range of environments, including marine habitats.
Fredrik Håkonsholm, Marit A. K. Hetland, Iren H. Löhr, Bjørn Tore Lunestad, Nachiket P. Marathe   +4 more
doaj   +1 more source

Dissemination of antibiotic resistance genes from antibiotic producers to pathogens [PDF]

Nature Communications, 2017
AbstractIt has been hypothesized that some antibiotic resistance genes (ARGs) found in pathogenic bacteria derive from antibiotic-producing actinobacteria. Here we provide bioinformatic and experimental evidence supporting this hypothesis.
Xinglin Jiang, Mostafa M. Hashim Ellabaan, Pep Charusanti, Christian Munck, Kai Blin, Yaojun Tong, Tilmann Weber, Morten O. A. Sommer, Sang Yup Lee   +8 more
openaire   +7 more sources

Shotgun metagenomics reveal antibiotic resistance genes associated with ESKAPE organisms in a polluted river in Trinidad

Heliyon
Antibiotic-resistant pathogens are often reported in aquatic environments due to pollution from anthropogenic activities. The introduction of untreated wastewater into rivers and streams makes these environments ideal reservoirs for the spread and ...
Aarti Pustam, Omar Ali, Stephen D.B. Ramnarine, Jayaraj Jayaraman, Adesh Ramsubhag   +4 more
doaj   +1 more source

Sampling and Pooling Methods for Capturing Herd Level Antibiotic Resistance in Swine Feces using qPCR and CFU Approaches. [PDF]

PLoS ONE, 2015
The aim of this article was to define the sampling level and method combination that captures antibiotic resistance at pig herd level utilizing qPCR antibiotic resistance gene quantification and culture-based quantification of antibiotic resistant ...
Gunilla Veslemøy Schmidt, Anders Mellerup, Lasse Engbo Christiansen, Marie Ståhl, John Elmerdahl Olsen, Øystein Angen   +5 more
doaj   +1 more source