Results 191 to 200 of about 217,789 (260)

Nanodiamonds as Bioactive Platforms to Modulate Microbial, Mammalian, and Vertebrate Systems

Advanced NanoBiomed Research, EarlyView.
Nanodiamonds (NDs) are biocompatible and antibacterial nanomaterials that support mammalian cell growth while inhibiting bacterial pathogens. NDs showed strong antibacterial activity, with Escherichia coli being more sensitive than Staphylococcus aureus. At 10 mg/mL, both bacteria exhibited ~8% viability.
Aaqil Rifai, Ayushi Priyam, Ahmed Rashed, Gebreselassie Addisu Tilaye, Kamal Poudel, Aaron G. Schultz, Richard J. Williams   +6 more
wiley   +1 more source

Cysteine Thioaldehydes: Photolytic Generation, Reactivity, and Biological Implications

Angewandte Chemie, EarlyView.
Photolysis of cysteine phenacylsulfides bearing non‐conjugating electron‐withdrawing substituents leads to high conversions into cysteine thioaldehydes through a Norrish type‐II pathway. This methodology enabled the study of the aqueous reactivity of these important biosynthetic intermediates, which, depending on peptide sequence, pH and buffer ...
Ardra Karthika, Matthew Murray, Guillermo Palop, Lee‐Ann J. Keane, Patrick McArdle, Nicholas D. J. Yates, Christopher D. Spicer, Alison Parkin, Martin A. Fascione, Eddie L. Myers   +9 more
wiley   +2 more sources

Antibiotic Use and Antibiotic Susceptibility of Common Environmental Bacterial Species in the Intensive Care Unit at Mbarara Regional Referral Hospital, Uganda. [PDF]

Cureus
Mwandah DC, Namakula MK, Kiprotich J, Babirye S, Kamoga NM, Masinde S, Nakiguli AB, Kiyimba K, Mugide N, Yadesa TM, Tusiimire J, Ttendo S, Oloro J, Bazira J, Agaba AG.   +14 more
europepmc   +1 more source

Modified Titanium Dental Implants: The Current Progress of Soft‐Tissue Integration Methods

Advanced NanoBiomed Research, EarlyView.
Dental implants are an established solution for tooth loss, yet achieving soft tissue integration (STI) around the transmucosal region remains a challenge. The natural tooth–gingiva interface is poorly replicated on titanium implants. This review explores surface modification strategies, ranging from surface chemistry and topography to biological ...
Daniel De Maria, Amy Gelmi, Peter C. Sherrell, Stefan Di Medio, Nhiem Tran, Kate Fox   +5 more
wiley   +1 more source

Deep Learning Enables Identification of Antimicrobial Peptides Through Mechanochromic Fingerprints

Angewandte Chemie, EarlyView.
We demonstrate a new platform for antimicrobial peptide identification by combining polydiacetylene, hyperspectral imaging, and deep learning. The trained model classifies distinct spectral fingerprints into 14 peptide classes with 96.79% accuracy, revealing previously hidden molecular information beyond conventional colorimetric sensing.
Jiali Chen, Che‐Lun Chin, Qingzhen Zhu, Ling Chao, Kaori Sugihara   +4 more
wiley   +2 more sources

Antibiotic susceptibility profile of bacterial isolates in paediatric cancer patients: a prospective cross-sectional study. [PDF]

BMC Pediatr
Hackman HK, Annison L, Arhin RE, Mensah AC, Aidoo EK, Appiah L, Gawugah RB, Nwachuku A, Agyei BA.   +8 more
europepmc   +1 more source

Nanostructured Deep Eutectic Systems in Healthcare: From Bioactive Solvents to Intelligent Biointerfaces, Wearables, and AI‐Driven Design

Advanced NanoBiomed Research, EarlyView.
Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley   +1 more source

Qualitative analysis of genomic mutations and antibiotic susceptibility testing of Pseudomonas aeruginosa isolates from chronic lung infections. [PDF]

PLoS One
Fluit AC, Bayjanov JR, Aguilar MD, Cantón R, Gilpin DF, Tunney MM, Ekkelenkamp MB.   +6 more
europepmc   +1 more source

Involvement of HemI, an ECF sigma factor, in hemin acquisition and antibiotic susceptibility in <i>Stenotrophomonas maltophilia</i>. [PDF]

Front Cell Infect Microbiol
Liao CH, Ku RH, Lu HF, Hu EW, Li LH, Yang TC.   +5 more
europepmc   +1 more source

Nanomotion-enabled ultra-rapid antibiotic susceptibility testing with magnetic bead-based pathogen enrichment for accelerated sepsis diagnostics. [PDF]

Sci Rep
Jóźwiak G, Pla Verge M, Luraschi-Eggemann A, Mestiri C, McSorley E, Wilson-Owen D, La Fauci S, García-Castillo M, Delarze E, Fromm K, Munch L, Vogel C, Balasopoulos D, Cathomen G, Reiter S, Świątkowski M, Totu R, Häussler S, Tenson T, Pagliara S, Cantón R, Greub G, Lisby G, Mullen W, Lockhart D, Cichocka D, Sturm A, ERADIAMR consortium.   +27 more
europepmc   +1 more source