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The Food Additive Benzaldehyde Confers a Broad Antibiotic Tolerance by Modulating Bacterial Metabolism and Inhibiting the Formation of Bacterial Flagella. [PDF]
Xiao X +6 more
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Adaptation to skin mycobiota promotes antibiotic tolerance inStaphylococcus aureus
Kowalski CH +4 more
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BatR: A novel regulator of antibiotic tolerance inPseudomonas aeruginosabiofilms
Piazza A +7 more
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A dietary source of antibiotic tolerance
Cell Metabolism, 2021Antibiotic tolerance enables microorganisms to survive the exposure to antibiotics and serves as a precursor to antibiotic resistance. In a recent issue of Nature Microbiology, Liu et al. (2021) describe that high-fat-diet-induced changes in the intestinal microbiome and metabolome facilitate the development of antibiotic tolerance by bacterial ...
Patrick, Lundgren +2 more
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Tolerance to antibiotics affects response
Science, 2020Bacterial tolerance to antibiotics reduces the ability to prevent ...
Andrew D, Berti, Elizabeth B, Hirsch
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Tolerance of staphylococci to bactericidal antibiotics
Injury, 2006Antibiotic therapy for deep-seated staphylococcal infections, especially when they are associated with artificial devices used for orthopedic surgery is often associated with failure. Standard anti-staphylococcal bactericidal antibiotics, such as semi-synthetic penicillins, cephalosporins, or glycopeptides, are effective when given prophylactically in ...
Vaudaux, Pierre, Lew, Daniel Pablo
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Antibiotic-induced disease tolerance
Nature Reviews Drug Discovery, 2020The tetracycline antibiotic doxycycline is shown to not only have direct antimicrobial effects but also promote disease tolerance mechanisms, including tissue repair and metabolic reprogramming.
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Microbial phenotypic heterogeneity and antibiotic tolerance
Current Opinion in Microbiology, 2007Phenotypic heterogeneity, defined as metastable variation in cellular parameters generated by epigenetic mechanisms, is crucial for the persistence of bacterial populations under fluctuating selective pressures. Diversity ensures that some individuals will survive a potentially lethal stress, such as an antibiotic, that would otherwise obliterate the ...
Neeraj, Dhar, John D, McKinney
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