Results 1 to 10 of about 1,060,384 (315)

A Scientific Roadmap for Antibiotic Discovery: A Sustained and Robust Pipeline of New Antibacterial Drugs and Therapies is Critical to Preserve Public Health [PDF]

, 2016
In recent decades, the discovery and development of new antibiotics have slowed dramatically as scientific barriers to drug discovery, regulatory challenges, and diminishing returns on investment have led major drug companies to scale back or abandon ...
Allan Coukell, Carolyn Shore, Elizabeth Jungman, Kathy Talkington, Pooja Kothari, Susan K. Urahn   +5 more
core  

Empiric antibiotic treatment of lesser pelvis inflammatory diseases at the hospital stage

Гинекология, 2013
Acute salpingo-oophoritis treatment is based on the general principles of infectious pathology management and implies appropriate antibacterial therapy, which is often empiric.
E V Eliseeva, I P Torgovitskaya, A V Tyrtyshnikova, Yu V Feoktistova, E A Poddubny, L M Grekhneva   +5 more
doaj  

The impact of antibiotic selection and interval time among advanced non‐small cell lung cancer patients receiving prior antibacterial treatment and first‐line chemotherapy

Cancer Medicine, 2022
Background To determine whether antibiotic use before chemotherapy is associated with chemotherapy responses and patient outcomes among NSCLC patients and define the optimal interval between chemotherapy initiation and antibiotic treatment. Materials and
Xiaoman Tian, Ting Mei, Min Yu, Yanying Li, Rui Ao, Youling Gong   +5 more
doaj   +1 more source

Antibiotic usage in organic pigs - Will consumers benefit from restricted antibiotic usage in organic pigs? [PDF]

, 2012
Spread of antibiotic resistance (AR) along the food-chain is a major food safety concern due to the risk of treatment failure of human foodborne infections. Can lower AR levels be claimed as a particular quality of organic pork due to the restrictions on
Anonymous, .
core  

Synergistic Activity of Fosfomycin, Ciprofloxacin, and Gentamicin Against Escherichia coli and Pseudomonas aeruginosa Biofilms [PDF]

, 2019
Gram-negative (GN) rods cause about 10% periprosthetic joint infection (PJI) and represent an increasing challenge due to emergence of antimicrobial resistance.
Di Luca, Mariagrazia, Gonzalez Moreno, Mercedes, Tkhilaishvili, Tamta, Trampuz, Andrej, Wang, Lei   +4 more
core   +1 more source

Peripheral Intravenous Therapy in Internal Medicine Department—Antibiotics and Other Drugs’ Consumption and Characteristics of Vascular Access Devices in 2-Year Observation Study

Antibiotics
Background: The aim of the study was to characterize the procedure of peripheral intravenous therapy (IT), including the characteristics of vascular access and related complications and qualitative and quantitative analyses of drug consumption. Materials
Piotr Piekiełko, Anna Mucha, Ewa Stawowczyk, Jadwiga Wójkowska-Mach   +3 more
doaj   +1 more source

Treatment of helicobacter pylori infection in atrophic gastritis [PDF]

, 2018
Helicobacter pylori (Hp) is a major human pathogen causing chronic, progressive gastric mucosal damage and is linked to gastric atrophy and cancer. Hp-positive individuals constitute the major reservoir for transmission of infection.
Annibale, B, Carabotti, M, Lahner, E
core   +1 more source

Brucellar Endocarditis of the Tricuspid Valve: A Case Report and Review of the Literature

Pathogens
Brucellar endocarditis is a rare entity commonly described as a severe disease associated with high mortality and generally requiring valve surgery for cure.
Evangelo Boumis, Pierangelo Chinello, Vincenzo Galati, Simone Topino, Francesca Gavaruzzi, Stefania Cicalini   +5 more
doaj   +1 more source

Distinct Bacterial Pathways Influence the Efficacy of Antibiotics against Mycobacterium tuberculosis

mSystems, 2020
Effective tuberculosis treatment requires at least 6 months of combination therapy. Alterations in the physiological state of the bacterium during infection are thought to reduce drug efficacy and prolong the necessary treatment period, but the nature of
Michelle M. Bellerose, Megan K. Proulx, Clare M. Smith, Richard E. Baker, Thomas R. Ioerger, Christopher M. Sassetti   +5 more
doaj   +1 more source

Mortality Risk and Antibiotic Therapy for Patients with Infections Caused by Elizabethkingia Species—A Meta-Analysis

Medicina
Background and Objectives: Patients with infections caused by Elizabethkingia species require prompt identification and effective antibiotic treatment since these spp.
Chienhsiu Huang, Sufang Kuo, Lichen Lin
doaj   +1 more source