Results 131 to 140 of about 868,436 (327)
A pangenome analysis of the plant pathogen Pseudomonas syringae reveals two novel natural product families that facilitate niche adaptation. Comprehensive genomic and chemical analyses uncover unique biosynthetic gene clusters linked to host specificity and environmental fitness.
Shuaibing Zhang+7 more
wiley +2 more sources
Growth-dependent bacterial susceptibility to ribosome-targeting antibiotics [PDF]
Bacterial growth environment strongly influences the efficacy of antibiotic treatment, with slow growth often being associated with decreased susceptibility. Yet in many cases the connection between antibiotic susceptibility and pathogen physiology remains unclear.
arxiv
Computational and AI‐Driven Design of Hydrogels for Bioelectronic Applications
This review highlights the role of AI in advancing hydrogel design for bioelectronics, exploring natural, and synthetic gels tailored for applications like wound healing, biosensing, and tissue engineering. It emphasizes the synergy between hydrogels, electronics, and AI in creating responsive, multifunctional systems, showcasing recent innovations ...
Rebekah Finster+2 more
wiley +1 more source
Drug-induced liver injury (DILI) has become a serious public health issue worldwide. Many drugs (chemotherapy drugs, fever-reducing medications, nonsteroidal anti-inflammatory drugs, immunosuppressants, antibiotics, antivirals, and antineoplastic drugs ...
Jin-Wei Zhao+3 more
doaj +1 more source
Background Medication safety in cancer patients receiving complex medication regimens is an important problem in various settings. Medication related events, interceptions and interventions are not well described in this area.
Marium Azim+3 more
doaj +1 more source
Bifurcation analysis and global dynamics of a mathematical model of antibiotic resistance in hospitals [PDF]
Antibiotic-resistant bacteria has posed a grave threat to public health by causing a number of nosocomial infections in hospitals. Mathematical models have been used to study the transmission of antibiotic-resistant bacteria within a hospital and the measures to control antibiotic resistance in nosocomial pathogens.
arxiv
Extended-spectrum β-lactamase-producing Gram-negative pathogens in community-acquired urinary tract infections: an increasing challenge for antimicrobial therapy [PDF]
Background: Extended-spectrum β-lactamases (ESBLs) are an increasing challenge in the treatment of urinary tract infections (UTIs), and also in the community.
Hasse, B.+4 more
core
This review summarizes recent developments in the design of photothermal charge transfer cocrystals for antibacterial therapy, cancer eradication, and bone regeneration, highlighting the design motivations and chemical principles of the strategies. It offers deep insights into the future development of advanced photothermal cocrystals for targeted ...
Arshad Khan+8 more
wiley +1 more source
Macromolecular platinum-based anticancer agents [PDF]
A thesis submitted to the faculty of Science, University of the Witwatersrand, in fulfillment of the degree of Doctor of Philosophy in Science Johannesburg, 2012Platinum is nowadays one of the best and widely used antitumor agents in cancer chemotherapy.
Diainabo, Kayembe Jacques
core