Results 151 to 160 of about 868,436 (327)

Procjena genotoksičnosti bleomicina i mitomicina C metodom kometnog testa [PDF]

open access: yes, 2004
Although chemotherapy targets cancer tissue, it also damages the DNA of non-cancer cells. The aim of this study was to evaluate the in vitro genotoxic potential of therapeutic concentrations of bleomycin and mitomycin C, added alone or in combination to ...
Mirta Milić, Nevenka Kopjar
core   +1 more source

Diamond Chemistry: Advances and Perspectives

open access: yesAngewandte Chemie International Edition, EarlyView.
In their review, Yang, Krueger, and Hamers highlight recent advances in diamonds that impact chemical scientists. Advances in growth of diamonds have yielded improved quality and lower cost, while new and emerging applications in areas such as energy storage, photo‐ and electro‐catalysis, sensing, and quantum science have expanded applications ...
Nianjun Yang   +2 more
wiley   +1 more source

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu   +11 more
wiley   +1 more source

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

open access: yesAngewandte Chemie International Edition, Accepted Article.
This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
wiley   +1 more source

In vitro sensitivity testing of human renal cell carcinoma with cytostatic agents and interferon alpha-2a [PDF]

open access: yes, 1991
AC Buzaid   +32 more
core   +1 more source

Engineering A Multifunctional Nanoenzyme Platform for Synergistic Melanoma Therapy: Integrating Enzyme Activity, Immune Activation, and Low‐Temperature Photothermal Effects

open access: yesAngewandte Chemie International Edition, Accepted Article.
Melanoma is characterized by rapid growth and high invasiveness, resulting in an exceptionally high malignancy and a significant propensity for metastasis. Current therapeutic modalities, such as chemotherapy and radiotherapy, exhibit limited efficacy due to severe side effects and immunosuppressive effects. Consequently, the development of precise and
Qihang Ding   +6 more
wiley   +1 more source

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