Results 161 to 170 of about 867,243 (251)

Rotenoids from the Roots of Vicia faba L. (Fabaceae): Structural Characterization, Cytotoxic Effects, and Molecular Docking

Chemistry &Biodiversity, EarlyView.
ABSTRACT The chemical study of the ethanolic extract from the roots of Vicia faba led to the isolation of two isoflavonoids, alfalone and 8‐O‐methylretusine, as well as a mixture of rotenoids, including clitoriacetal and clitoriacetal B, the latter of which is reported for the first time.
Victor Menezes Sipoloni, João Victor Silva‐Silva, Elthon G. Ferreira, Eric Yoshitaka Lee, João Marcos Batista Junior, Miriam Uemi, Lívia Soman de Medeiros, Paula C. Jimenez, Thiago A. M. Veiga   +8 more
wiley   +1 more source

Ibrutinib-Induced Perianal Rash Complicated by Bacterial Infection in a Patient With Chronic Lymphocytic Leukemia: A Case Report and Literature Review. [PDF]

Cureus
Singh J, Gupta P, Vargas J, Kudelka A, Kobe M, Rocca N.   +5 more
europepmc   +1 more source

Identification of a l‐Threonine‐Utilizing Hydrazine Synthetase for Thrazarine Biosynthesis in Streptomyces coerulescens MH802‐fF5

ChemBioChem, EarlyView.
A putative thrazarine biosynthetic gene cluster is discovered in the genome sequence of Streptomyces coerulescens MH802‐fF5. In vivo and in vitro analyses of ThzN, a hydrazine synthetase with cupin and methionyl‐tRNA synthetase‐like domains encoded in the cluster, showed that it synthesizes a key intermediate of thrazarine by catalyzing condensation ...
Yusuke Shikai, Hideyuki Muramatsu, Masayuki Igarashi, Yohei Katsuyama, Yasuo Ohnishi   +4 more
wiley   +1 more source

Chemotherapy-induced febrile neutropenia followed by acute hepatitis E virus infection in rectal cancer patient with synchronous liver and lung metastasis: a case report. [PDF]

BMC Infect Dis
Zhang D, Chen Z, Wu J, Ning N, Chen L, Tian X.   +5 more
europepmc   +1 more source

Boosting Antibiotic Efficacy of Azole Drugs against Methicillin‐Resistant Staphylococcus Aureus by Coordination to Rhenium Carbonyl Complexes

ChemBioChem, EarlyView.
Coordination of antifungal azoles to rhenium di‐ and tricarbonyl complexes results in compounds with enhanced antimicrobial efficacy—up to 32‐fold minimum inhibitory concentration improvement—against methicillin‐sensitive and methicillin‐resistant Staphylococcus aureus over parent azoles.
Kevin Schindler, Gozde Demirci, Bettina Tran, Sara Nasiri Sovari, Youri Cortat, Nicolas F. Rosa De Sousa, Carola Velti, Baptiste Chapuis, Aurélien Crochet, Aleksandar Pavic, Jelena Djuris, Stefan Salentinig, Fabio Zobi   +12 more
wiley   +1 more source

Improved Clinical Outcomes with Appropriate Meropenem De-escalation in Patients with Febrile Neutropenia. [PDF]

J Glob Infect Dis
Luu T, Fan A, Shaw R, Dalal H, Adams J, Santarossa M, Reid G, Tsai S, Clark NM, Albarillo FS.   +9 more
europepmc   +1 more source

Development of Novel Anticancer Pyrazolopyrimidinones Targeting Glioblastoma

ChemMedChem, Accepted Article.
Glioblastoma (GBM) is the most common and aggressive malignant grade IV brain tumour and is one of the most difficult types of brain cancer to treat with a high incidence of resistance to traditionally used chemotherapeutics. Pyrazolopyrimidinones are fused nitrogen‐containing heterocyclic systems which are a scaffold in several bioactive drugs and ...
Kate Byrne, Natalia Bednarz, Ciara McEvoy, John C. Stephens, James F. Curtin, Gemma Kinsella   +5 more
wiley   +1 more source

Medication Purchases Are Associated With the Number of Dental Treatments. [PDF]

Clin Exp Dent Res
Frankenhaeuser F, Källmén H, Meurman J, Korpi E, Söder B.   +4 more
europepmc   +1 more source

Development of Water‐Dispersible CuS Nanoparticles for Chemo–Photothermal Therapy and Photoacoustic Application

ChemPhysChem, EarlyView.
Water‐dispersible CuS nanoparticles are developed by the soft chemical approach using phosphorylethanolamine as a surface passivation agent for chemo–photothermal therapy and photoacoustic application. Photothermal therapy (PTT) is a promising treatment option for cancer. However, biocompatibility, water dispersibility, and good photoresponsiveness are
Sonali Gupta, Bijaideep Dutta, Subhadip Paul, Ratan K. Saha, Kanhu C. Barick, Puthusserickal A. Hassan   +5 more
wiley   +1 more source

Therapeutic Potential of <i>Ficus benjamina</i>: Phytochemical Identification and Investigation of Antimicrobial, Anticancer, Pro-Wound-Healing, and Anti-Inflammatory Properties. [PDF]

Molecules
Dahan A, Yarmolinsky L, Budovsky A, Khalfin B, Ben-Shabat S.   +4 more
europepmc   +1 more source