Results 191 to 200 of about 868,436 (327)

Causes of drug-induced photosensitivity: an analysis using FDA adverse event reporting system database. [PDF]

Sci Rep
Ge L, Huang X, Dong Z, Zhong T.
europepmc   +1 more source

Bioactives From Brown Algae: Antioxidant, Anti‐Inflammatory, Anticancer, and Antimicrobial Potential

ChemBioEng Reviews, EarlyView.
This review explores key bioactives in brown algae and their antioxidant, anti‐inflammatory, anticancer, and antimicrobial properties. Covering studies from 2014 to 2024, it highlights their relevance in pharmaceuticals, nutraceuticals, cosmetics, and foods, while addressing challenges and future directions to unlock their full potential.
Irvin Fonseca‐Barahona, Kaveh Shahbaz, Saeid Baroutian   +2 more
wiley   +1 more source

Silver nanoparticles derived from Streptomyces sp. YJD18 with multifunctional biomedical applications. [PDF]

Sci Rep
Niu L, Lin Z, Hu W, Yang D, Shen H, Guo F.   +5 more
europepmc   +1 more source

Inhibition of Surfactin Biosynthesis in Bacillus Subtilis Using Cell‐Permeable Adenylation Domain Inhibitors

ChemBioChem, EarlyView.
L‐Leu‐AMS‐based adenylation domain inhibitors with the modification of 2′‐OH in the adenosine skeleton are synthesized. Coupled with affinity‐based protein profiling of nonribosomal peptide synthetases (NRPSs), their activities toward surfactin‐NRPSs in Bacillus subtilis are evaluated.
Fumihiro Ishikawa, Sho Konno, Hideaki Kakeya, Genzoh Tanabe   +3 more
wiley   +1 more source

Synthesis and Evaluation of Pseudoglucosinolates Releasing Isothiocyanates in the Presence of Azoreductases

ChemBioChem, EarlyView.
An expansion of the concept of pseudoglucosinolates (psGSLs) is reported introducing the first azoreductase‐responsive psGSL‐based probe releasing an isothiocyanate under simultaneous fluorescence turn‐on in the presence of AzoR, an azoreductase from Escherichia coli.
Aishi Chakrabarti, Charity S. G. Ganskow, Mervic D. Kagho, Claire. C. Jimidar, Lorenz Wiese, Neslihan Beyazit, Ulrike Beutling, Margarita Seeger, Silvana Smits, Stella Nyström, Anne Farewell, Anett Schallmey, Mark Brönstrup, Philipp Klahn   +13 more
wiley   +1 more source

Ibrutinib-Induced Perianal Rash Complicated by Bacterial Infection in a Patient With Chronic Lymphocytic Leukemia: A Case Report and Literature Review. [PDF]

Cureus
Singh J, Gupta P, Vargas J, Kudelka A, Kobe M, Rocca N.   +5 more
europepmc   +1 more source

PHP58 Direct Cost of Adverse Drug Reaction Treatment in Hospitalized Patients in Nakhon Pathom Hospital, Thailand [PDF]

, 2012
Auekusonsomboon, K., Junklub, J., Kongchat, J., Kornkaew, J., Maitreemit, P., Sonchaem, T.   +5 more
core   +1 more source

Unveiling New Triazoloquinoxaline‐Based PROTACs Designed for the Selective Degradation of the ncBAF Chromatin Remodeling Subunit BRD9

Chemistry – A European Journal, EarlyView.
We present new BRD9‐targeting degraders featuring a chemical warhead and E3 ligase ligand that distinctly differ from the typical chemical units used for BRD9 degradation. Specifically, we identified two VHL‐based PROTACs (2 and 9) based on a [1,2,4]triazolo[4,3‐a]quinoxaline scaffold that effectively and selectively degrade BRD9 and exhibit ...
Martina Pierri, Guglielmo Bove, Erica Gazzillo, Ester Colarusso, Francesca Scala, Giacomo Pepe, Stefania Terracciano, Maria Giovanna Chini, Nicla Simonelli, Ines Bruno, Angela Nebbioso, Pietro Campiglia, Giuseppe Bifulco, Lucia Altucci, Nunzio Del Gaudio, Gianluigi Lauro   +15 more
wiley   +1 more source

Anthrapyrazole Antineoplastic Antibiotic [PDF]

, 2020
openaire   +1 more source

Novel quinazolinones active against multidrug‐resistant Mycobacterium tuberculosis: synthesis, antimicrobial evaluation and in silico exploration of PonA1 as a potential target

ChemMedChem, Accepted Article.
Quinazolinone derivatives have emerged as promising scaffolds in antimicrobial drug discovery. This work focuses on the design, synthesis, and evaluation of novel quinazolinone‐based compounds and predicts their potential to interact with mycobacterial penicillin‐binding proteins (PBPs).
MAREK KERDA, Daria Nawrot, Petr Slechta, Mirek Domanský, Asal Askari, Hanieh Kamangar, Ondřej Janďourek, Klára Konečná, Pavla Paterová, Ingrid Hlbočanová, Miloslav Macháček, Matteo Mori, Fiorella Meneghetti, Martin Doležal, Jan Zitko, Ghada Bouz   +15 more
wiley   +1 more source