Results 221 to 230 of about 867,243 (251)

Enzymatic release of nitric oxide from L-alanosine, an antineoplastic antibiotic

Biochemical and Biophysical Research Communications, 1982
Abstract L-Alanosine is an antineoplastic drug which is the 3-isonitramino analog of L -aspartic acid. The drug is known to be metabolized to the corresponding 2-oxo acid. Unlike the parent amino acid, the 2-oxo acid is unstable under mild conditions.
Theodore A. Alston, Harold J. Bright
openaire   +3 more sources

Daunomycin: A New Antibiotic with Antitumor Activity

Tumori Journal, 1963
Daunomycin is a new antibiotic isolated from cultures of Streptomyces peucetius. For its physicochemical characteristics it may belong to the group of antibiotics described by Ollis and Sutherland (11). The toxico-pharmacologic studies of Daunomycin administered i.v. to mice and rats indicated an acute LD50 value of 15-20 mg/kg.
Gaetani M, Dorigotti L, Dimarco A, M Soldati, Bellini O   +4 more
openaire   +4 more sources

Preliminary Pharmacokinetics of Streptozotocin, an Antineoplastic Antibiotic

The Journal of Clinical Pharmacology, 1977
A. J. Weiss, R. W. Manthei, A. B. Adolphe, W. M. Troetel, E. D. Glasofer   +4 more
openaire   +3 more sources

[Clinical experiences with antineoplastic antibiotic sarkomycin].

Gan, 1954
Hiroshi Takahashi, Shoichi Sumita, Yoshiki Shirasuga, Masae Ida, Shunji Ishiyama, Susumu Izeki, Isao Ishiyama, Susumu Shirado   +7 more
openaire   +3 more sources

Resonance Rayleigh scattering spectra for studying the interaction of anthracycline antineoplastic antibiotics with some anionic surfactants and their analytical applications.

Analytica Chimica Acta, 2007
Shao-pu Liu, Fen Wang, Zhongfang Liu, Xiaoli Hu, Aoer Yi, Hui Duan   +5 more
semanticscholar   +1 more source

[Structure of the antineoplastic antibiotic variamycin].

Bioorganicheskaia khimiia, 1991
The results of the structural study of antitumor antibiotic variamycin and its peracetyl derivative by 1H-and 13C-NMR spectroscopy are reported. Structures of carbohydrate chains of the antibiotics molecule are revised. Variamycin is shown to be 2-[beta-cymmarosyl(1-3)-beta-oliosyl (1-3)-beta-olivosyl]-6-[beta-olivosyl (1-3)-beta-olivosyl ...
A S, Shashkov, D V, Iashunskiĭ, Iu V, Zhdanovich, G B, Lokshin   +3 more
openaire   +1 more source

SYNTHESIS OF POTENTIAL ANTINEOPLASTIC AGENTS. 33. BETA-DIKETONE ANALOGS OF THE GLUTARIMIDE ANTIBIOTICS.

Journal of Medicinal Chemistry, 1964
R. Struck, H. Schaeffer, C. A. Krauth, R. T. Kemp, Y. Shealy, J. Montgomery   +5 more
semanticscholar   +1 more source

ANTITUMOR ANTIBIOTICS. VI. CORRELATION OF COVALENT CROSS-LINKING OF DNA BY BIFUNCTIONAL AZIRIDINOQUINONES WITH THEIR ANTINEOPLASTIC ACTIVITY

, 1976
M. H. Akhtar, A. Begleiter, Douglas S. Johnson, J. Lown, L. McLaughlin, S. Sim   +5 more
semanticscholar   +1 more source

Antineoplastic isnʼt antibiotic

Nursing, 2004
openaire   +2 more sources

[Secondary microbial metabolites with potentials for antineoplastic actions: antineoplastic antibiotics and immunopotentiators].

Gan to kagaku ryoho. Cancer & chemotherapy, 1983
Studies of microbial secondary metabolites are being continued for the purpose of finding compounds useful in the treatment of curing cancer. Derivatives and analogs which have lower characteristic toxicities of parent antitumor antibiotics such as adriamycin, bleomycin, mitomycin, etc. are being developed.
openaire   +1 more source