Results 151 to 160 of about 2,694,182 (391)

Clinical characteristics and antimicrobial therapy of healthcare-associated carbapenem-non-susceptible gram-negative bacterial meningitis: a 16-year retrospective cohort study

open access: yesBMC Infectious Diseases
Objective Healthcare-associated Gram-negative bacterial meningitis is a substantial clinical issue with poor outcomes, especially for neurosurgical patients.
Jiyan Xu   +7 more
doaj   +1 more source

PK/PD Modeling as a Tool for Predicting Bacterial Resistance to Antibiotics: Alternative Analyses of Experimental Data

open access: yesАнтибиотики и Химиотерапия, 2020
Postexposure number of mutants (NM) is a conventional endpoint in bacterial resistance studies using in vitro dynamic models that simulate antibiotic pharmacokinetics.
M. V. Golikova   +3 more
doaj  

Removal of Steroid Hormone Micropollutants by an Electrochemical Carbon Nanotube Membrane Flow‐Through Reactor: Role of Concentration and Degradation Mechanisms

open access: yesAdvanced Functional Materials, EarlyView.
A flow‐through electrochemical membrane reactor equipped with a carbon nanotube membrane eliminates the mass transfer limitation, achieving removals >97.5% for steroid hormone (SH) micropollutants through electrochemical adsorption and degradation, over a broad initial concentration varying from 50 to 106 ng L−1.
Siqi Liu   +2 more
wiley   +1 more source

Synthesis and Antibacterial Activity of ll-O-(Benzoxaborole-Aminoalkylcarbamoyl) Derivatives of Macrolide Antibiotic Azithromycin

open access: yesАнтибиотики и Химиотерапия, 2020
Benzoxaborole, a structure in medicinal chemistry privileged due to its desirable physicochemical and drug-like properties, was used for the synthesis of azithromycin-benzoxaborole conjugates in which benzoxaborole fragment was attached to the 11-hydroxy
S. S. Printsevskaya   +5 more
doaj  

DENTA: A Dual Enzymatic Nanoagent for Self‐Activating Tooth Whitening and Biofilm Disruption

open access: yesAdvanced Functional Materials, EarlyView.
The nanoapatite with dual enzymes (DENTA) accumulates in dentinal tubules, reducing hypersensitivity caused by dental nerve exposure and facilitating continuous ROS generation through salivary glucose for effective, long‐term whitening. The dentin structures remain non‐destructive due to the low concentration of ROS, demonstrating excellent cell ...
Junseok Kim   +13 more
wiley   +1 more source

ANN for Predicting Antibiotic Susceptibility [PDF]

open access: yes, 2016
: In this research, an Artificial Neural Network (ANN) model was developed and tested to predict efficiency of antibiotics in treating various bacteria types. Attributes that were taken in account are: organism name, specimen type, and antibiotic name as
Ahmed, Maaruf, Randa, Qassas
core  

Antibiotic Overproduction in Streptomyces coelicolor A3(2) Mediated by Phosphofructokinase Deletion [PDF]

open access: hybrid, 2008
Irina Borodina   +6 more
openalex   +1 more source

ANTIBIOTIC RESISTANCE

open access: yesCritical Care Clinics, 1998
Antibiotic resistance is an increasing problem in many parts of the world. Antibiotic resistance has been associated with the use of some antibiotics but not with others. Due to the overuse of antibiotics with a high resistance potential, there has been an increase of resistance with certain bacteria, e.g., Staphylococcus aureus, Pseudomonas aeruginosa
openaire   +3 more sources

Host‐Directed Biomaterials for Combatting Bloodstream Infections: From Macrocyclic Peptides to Immune‐Activating Cell Backpacks

open access: yesAdvanced Functional Materials, EarlyView.
Bloodstream infections (BSI) are one of the leading causes of mortality and morbidity in both civilian and military populations. This paper summarizes recent progress in novel treatment strategies to manage BSI arising from both bacterial and fungal pathogens using molecules, particles, and materials to elicit host‐directed immunity.
Thomas Thomou   +11 more
wiley   +1 more source

Synthesis and Biological Activity of New Antimicrobial Agents - Hybrid Derivatives of Maleimides and Triindolylmethanes

open access: yesАнтибиотики и Химиотерапия, 2020
Methods for the synthesis of hybrid molecules that combine the structure of a highly active antimicrobial compounds - tris(1-alkylindol-3-yl)methylium as well as 3-(indol-1-yl)maleimides that previously showed activity against some protein kinases have ...
S. N. Lavrenov   +11 more
doaj  

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