Results 201 to 210 of about 2,694,182 (391)

The global distribution of the macrolide esterase EstX from the alpha/beta hydrolase superfamily

Communications Biology
Macrolide antibiotics, pivotal in clinical therapeutics, are confronting resistance challenges mediated by enzymes like macrolide esterases, which are classified into Ere-type and the less studied Est-type.
Jiafu Lin, Hua Lv, Tiantian Wang, Hongkun Tao, Yi Zhong, Yang Zhou, Yibo Tang, Feng Xie, Guoqing Zhuang, Changwen Xu, Yiwen Chu, Xinrong Wang, Yongqiang Yang, Tao Song   +13 more
doaj   +1 more source

Clinical applications of population pharmacokinetic models of antibiotics: Challenges and perspectives

, 2018
Femke de Velde, Johan W. Mouton, Brenda C. M. de Winter, Teun van Gelder, Birgit C. P. Koch   +4 more
openalex   +2 more sources

A Novel Core–Shell Hydrogel 3D Model for Studying Macrophage Mechanosensing and Foreign Body Giant Cell Formation

Advanced Healthcare Materials, EarlyView.
The foreign body response (FBR) to biomaterials is primarily driven by macrophages, which often fuse into destructive foreign body giant cells (FBGCs). To address the limited understanding of FBGC formation, a novel microscale core–shell hydrogel 3D model is developed using heterogeneous alginate‐collagen microcapsules with varying stiffness, offering ...
Manisha Mahanty, Wenquan Ou, Xiaoping Zhu, Jonathan S Bromberg, Xiaoming He, Shaik O. Rahaman   +5 more
wiley   +1 more source

Association of Antibiotic Resistance, Cell Adherence, and Biofilm Production with the Endemicity of NosocomialKlebsiella pneumoniae [PDF]

, 2018
María Dolores Alcántar‐Curiel, Carmen Alejandra Ledezma-Escalante, Ma Dolores Jarillo-Quijada, Catalina Gayosso-Vázquez, Rayo Morfín‐Otero, Eduardo Rodríguez-Noriega, María L. Cedillo‐Ramírez, José Ignacio Santos-Preciado, Jorge A. Girón   +8 more
openalex   +1 more source

A Novel Brain Penetrable Nanocarrier Delivers Brain‐Derived Neurotrophic Factor to Treat Alzheimer's Disease

Advanced Healthcare Materials, EarlyView.
A novel blood‐brain barrier‐penetrating terpolymer nanoparticle to deliver brain‐derived neurotrophic factor (BDNF) for the treatment of Alzheimer's disease (AD) is designed. The BDNF‐TPN significantly enhances BDNF accumulation in the brain following intravenous injection, reduces apoptosis and neuroinflammation, thus promoting neuronal survival and ...
Lily Yi Li, Elliya Park, Chunsheng He, Azhar Z. Abbasi, Pei Zhi, Paul E. Fraser, Andrew M. Rauth, Jeffery T. Henderson, Xiao Yu Wu   +8 more
wiley   +1 more source

Systemic Antibiotic Prophylaxis in Maxillofacial Trauma: A Scoping Review and Critical Appraisal [PDF]

, 2022
Femke Goormans, Ruxandra Coropciuc, Maximilien Vercruysse, Isabel Spriet, Robin Willaert, Constantinus Politis   +5 more
openalex   +1 more source

Antibiotics: past, present and future.

Current Opinion in Microbiology, 2019
M. Hutchings, A. Truman, B. Wilkinson
semanticscholar   +1 more source

Decellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis

Advanced Healthcare Materials, EarlyView.
Decellularized liver extracellular matrix scaffolds provide a platform to study dormant liver‐metastatic colorectal cancer. They induce reversible dormancy, in combination with nutrient depletion and low dose chemotherapy, through cell cycle arrest and chemotherapy resistance.
Sabrina N. VandenHeuvel, Lucia L. Nash, Abigail J. Clevenger, Claudia A. Collier, Oscar R. Benavides, Sanjana Roy, Brinlee Goggans, Aelita Salikhova, Anvitha Tharakesh, Svasti Haricharan, Amber N. Stratman, Scott Kopetz, Alex J. Walsh, Shreya A. Raghavan   +13 more
wiley   +1 more source

Antibiotic Susceptibility Testing of the Gram-Negative Bacteria Based on Flow Cytometry [PDF]

, 2016
Claude Saint‐Ruf, Steve Crussard, Christine Franceschi, Sylvain Orenga, Jasmine Ouattara, Mahendrasingh Ramjeet, Jérémy Surre, Ivan Matić   +7 more
openalex   +1 more source

Antibiotics [PDF]

Paediatrics & Child Health, 1998
openaire   +2 more sources