Results 31 to 40 of about 1,145,667 (304)

Antimicrobial activity of ceftobiprole and comparator agents when tested against gram-positive and -negative organisms collected across China (2016–2018)

BMC Microbiology, 2022
Background Ceftobiprole is a fifth-generation cephalosporin which has been reported to have broad antibacterial spectrum when tested against bacteria collected from other countries except China.
Yin Dandan, Wu Shi, Yang Yang, Zheng Yonggui, Demei Zhu, Guo Yan, Fupin Hu   +6 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Ebosin Attenuates the Inflammatory Responses Induced by TNF-α through Inhibiting NF-κB and MAPK Pathways in Rat Fibroblast-Like Synoviocytes

Journal of Immunology Research, 2022
Tumor necrosis factor-α (TNF-α) lies at the apex of signal transduction cascades that results in induced destruction of joints in rheumatoid arthritis. It is therefore of great medicinal interest to modulate the cellular responses to TNF-α.
Yang Zhang, Lifei Wang, Liping Bai, Rong Jiang, Jianbo Wu, Yuan Li   +5 more
doaj   +1 more source

ANTIPSEUDOMONAL ANTIBIOTICS

Medical Clinics of North America, 2001
Pseudomonas aeruginosa is responsible for a variety of nosocomial infections associated with high morbidity and mortality, involving the immunocompromised and immunocompetent host. There are several groups of antipseudomonal antibiotics available today: antipseudomonal penicillins (carboxy and ureido penicillins), antipseudomonal cephalosporins ...
Giamarellou, H, Antoniadou, A
openaire   +3 more sources

New antibiotics for antibiotic-resistant bacteria [PDF]

F1000 Biology Reports, 2009
The need for new antibiotics to effectively treat antibiotic-resistant infections remains unfulfilled. Despite the well-publicised concern over this issue, only two novel antibiotic classes have been introduced in the past 20 years alongside several new agents of existing classes.
Stubbings, William, Labischinski, Harald
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Application of Basic Pharmacology and Dispensing Practice of Antibiotics in Accredited Drug-Dispensing Outlets in Tanzania. [PDF]

, 2013
Provision of pharmaceutical services in accredited drug-dispensing outlets (ADDOs) in Tanzania has not been reported. This study compared the antibiotics dispensing practice between ADDOs and part II shops, or duka la dawa baridi (DLDBs), in Tanzania ...
Minzi, O. M., Manyilizu, Vs, Manyilizu, V. S., Minzi, Om   +3 more
core   +1 more source

Evaluation of the Immunochromatographic NG-Test Carba 5, RESIST-5 O.O.K.N.V., and IMP K-SeT for Rapid Detection of KPC-, NDM-, IMP-, VIM-type, and OXA-48-like Carbapenemase Among Enterobacterales

Frontiers in Microbiology, 2021
BackgroundEnterobacterales are the most common pathogens for nosocomial infections. The emergence and spread of KPC, NDM, and OXA-48-like carbapenemase-producing Enterobacterales with their extensively drug-resistant characteristics have posed great ...
Renru Han, Renru Han, Yan Guo, Yan Guo, Mingjia Peng, Mingjia Peng, Qingyu Shi, Qingyu Shi, Shi Wu, Shi Wu, Yang Yang, Yang Yang, Yonggui Zheng, Yonggui Zheng, Dandan Yin, Dandan Yin, Fupin Hu, Fupin Hu   +17 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Are patient views about antibiotics related to clinician perceptions, management and outcome? A multi-country study in outpatients with acute cough

, 2013
Background: outpatients with acute cough who expect, hope for or ask for antibiotics may be more unwell, benefit more from antibiotic treatment, and be more satisfied with care when they are prescribed antibiotics.
Francis, N.K., Hasse Melbye, Butler, Christopher, GRACE Project Group, Little, P, Verheij, Theo J. M., Francis, N., Nick Francis (475899), Verheij, Theo J.M., Samuel Coenen (397250), Paul Little (475903), Butler, C.C., Goossens, Herman, Nuttall, Jacqui, Kelly, M., Mark Kelly, Little, P., Melbye, H., Goossens, H., Samuel Coenen, Hasse Melbye (475905), Melbye, H, Jacqui Nuttall, Kelly, Mark, Melbye, Hasse, Paul Little, Kerenza Hood, Herman Goossens, Mark Kelly (475900), Herman Goossens (305529), Nuttall, J, Nuttal, Jacqui, Butler, Christopher C., Goossens, H, Hood, K., Little, Paul, Coenen, S, Grace Project Group, x, Jacqui Nuttall (475902), Theo J M Verheij, Verheij, T.J., Theo J. M. Verheij (475904), Verheij, TJ, Francis, Nicholas, Coenen, S., Nuttall, J., Francis, Nick, Nick Francis, Hood, K, Coenen, Samuel, Christopher C Butler, Kerenza Hood (475901), Christopher C. Butler (475906), Kelly, M, Verheij, Th.J.M., Francis, N, Kelly, M.J., Hood, Kerenza, Butler, CC   +58 more
core   +1 more source