Results 21 to 30 of about 9,920 (163)

Case report: MELAS and concomitant presumed antiphospholipid antibody syndrome in an adult woman

Frontiers in Neurology, 2022
Mitochondrial encephalomyopathy, lactic acidosis, stroke-like episodes, and other features (short stature, headaches, seizures, and sensorineural hearing loss) constitute characteristics of MELAS syndrome.
Sirisha Nouduri, Rajiv Padmanabhan, Richard Hicks, Mary-Alice Abbott, Dennis O'Brien, Gottfried Schlaug   +5 more
doaj   +1 more source

Rapid detection of anticardiolipin antibodies [PDF]

American Journal of Hematology, 1998
A rapid screening method for the detection of antiphospholipid antibodies is described. Dense, red dyed polystyrene beads coated with cardiolipin were incubated with test sera for a short period of time, then added to a microtube containing anti-human IgG in a gel provided within a pre-cast card (DiaMed ID Microtyping System).
M W, Stewart, T, McKay, P, Schwind, P A, Gordon   +3 more
openaire   +2 more sources

Prothrombotic Activation of Platelet Pannexin‐1 Channels in Antiphospholipid Syndrome

Arthritis &Rheumatology, EarlyView.
Objective ATP is released from platelets through both degranulation and pannexin‐1 (PANX1) channels. ATP then activates P2X receptors to amplify platelet activation via calcium‐dependent signaling. The objective of this study was to evaluate the role of platelet PANX1 channels in the pathophysiology of antiphospholipid syndrome (APS), an acquired ...
Bruna de Moraes Mazetto Fonseca, Somanathapura K. NaveenKumar, Srilakshmi Yalavarthi, Kavya Sugur, Thalia G. Newman, Claire K. Hoy, Cyrus Sarosh, Jordan K. Schaefer, Ajay Tambralli, Jacqueline A. Madison, Yu Zuo, Fernanda A. Orsi, Michael Holinstat, Jason S. Knight   +13 more
wiley   +1 more source

Cognitive functions and autoantibodies in patients with systemic lupus erythematosus

Psychiatria i Psychologia Kliniczna, 2016
Introduction: Autoantibodies may occur in the course of various diseases. In the case of systemic lupus erythematosus the presence of specific autoantibodies is included in the classification criteria of the disease.
Anna Bogaczewicz, Jakub Ząbek, Tomasz Sobów, Ewa Robak, Jarosław Bogaczewicz, Anna Woźniacka   +5 more
doaj   +1 more source

Molecular Stratification of Antiphospholipid Syndrome Through Integrative Analysis of the Whole‐Blood RNA Transcriptome

Arthritis &Rheumatology, EarlyView.
Objective Antiphospholipid syndrome (APS) is a thromboinflammatory disorder characterized by clinical and mechanistic heterogeneity that complicates early diagnosis and hinders targeted treatment. We aimed to identify distinct molecular endotypes among antiphospholipid antibody (aPL)–positive patients using whole‐blood transcriptomics.
Amala Ambati, Feiyang Ma, Katarina Kmetova, Sherwin Navaz, Claire K. Hoy, Cyrus Sarosh, Ajay Tambralli, Erika Navarro‐Mendoza, Johann E. Gudjonsson, J. Michelle Kahlenberg, Jacqueline A. Madison, Alí Duarte‐García, Jason S. Knight, Yu Zuo   +13 more
wiley   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

Vascular dysfunction in women with recurrent pregnancy loss: Possible association with antiphospholipid antibodies

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 206-214, April 2025.
Abstract Objective Antiphospholipid antibodies (aPL) are recognized to have a pivotal role in recurrent pregnancy loss (RPL) and cardiovascular disease. Therefore, we assessed the vascular function of women with RPL and examined the association with each type of aPL.
Titi Yang, Emi Okada, Maho Todoroki, Siyu Liu, Rukmali Athurupana, Kumie Kataoka, Chiaki Kashino, Takashi Mitsui, Toru Hasegawa, Yasuhiko Kamada, Hisashi Masuyama, Mikiya Nakatsuka   +11 more
wiley   +1 more source

Studying the Role of IFN-γ, Vitamin C, SOD, LH, FSH, APA and ACA in Toxoplasma gondii Infected Miscarriage Women

مجلة بغداد للعلوم, 2019
This study is designed to detect the level of cytokine IFN-γ concentration, and some antioxidants, including super oxide dismutase (SOD) and Vitamin C, and to estimate the level of sex hormones (FSH and LH), and to determine auto-antibodies ...
Ismael et al.
doaj   +1 more source

Long‐Term Dermoscopic Evolution of Reticular Erythematous Mucinosis: Case Report

JEADV Clinical Practice, EarlyView.
ABSTRACT Reticular erythematous mucinosis is a rare dermatosis with a challenging diagnosis. To date, its dermoscopic features have not been well characterised in the literature. Only a limited number of case reports have described dermoscopic findings that may be indicative of the disorder, including the presence of dotted and linear vessels, as well ...
Grażyna Kamińska‐Winciorek, Karolina Zarańska, Anastazja Szlauer‐Stefańska, Jacek Pająk, Sebastian Giebel   +4 more
wiley   +1 more source

A case of pulmonary tuberculosis presenting as diffuse alveolar haemorrhage: is there a role for anticardiolipin antibodies?

BMC Infectious Diseases, 2010
Background Diffuse alveolar haemorrhage (DAH) has been rarely reported in association with pulmonary infections. Case Presentation We report the case of a 43 year old immunocompetent man presenting with dyspnoea, fever and haemoptysis.
Lauria Francesco N, Tommasi Chiara, Corpolongo Angela, Marruchella Almerico, Narciso Pasquale   +4 more
doaj   +1 more source