Results 1 to 10 of about 4,826 (241)
Malassezia globosa lipidome: The dynamics of uptake and secreted lipids [PDF]
VirulenceMalassezia globosa plays a crucial role as part of the human skin’s mycobiome. However, this yeast has been detected in other niches, such as the gut.
Catherine Eliana Cabrera Díaz +3 more
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Cell Death and Disease, 2022 The role played by lipids in the process of granulocytic differentiation activated by all-trans retinoic acid (ATRA) in Acute-Promyelocytic-Leukemia (APL) blasts is unknown.
Maurizio Gianni’ +12 more
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Cell Reports, 2020 Summary: Cardiolipin (CL) is a phospholipid specific for mitochondrial membranes and crucial for many core tasks of this organelle. Its acyl chain configurations are tissue specific, functionally important, and generated via post-biosynthetic remodeling.
Gregor Oemer +12 more
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The lipidome of the kidney tubules of ob/ob mice is affected at the infralesional level [PDF]
Cell Death DiscoveryWhether changes in tubular lipidomic composition precede the onset of observable kidney damage in obesity is unknown. We manually isolated the proximal convoluted tubule (PCT), the cortical thick ascending limb of Henle’s loop (cTAL) and the cortical ...
Lydie Cheval +4 more
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Cardiolipin acyl chain composition tailors the conformation of mammalian ATP synthase dimers [PDF]
Communications ChemistryThe interplay between ATP synthase dimers and the four-tailed lipid cardiolipin (CL) shapes mitochondrial cristae structure and function. In the mitochondrial disorder Barth syndrome (BTHS), cristae membranes accumulate a less unsaturated, three-tailed ...
M. Makowski +2 more
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Cardiolipins and biomembrane function [PDF]
BBA - Biomembranes, 1992 Evidence is discussed for roles of cardiolipins in oxidative phosphorylation mechanisms that regulate State 4 respiration by returning ejected protons across and over bacterial and mitochondrial membrane phospholipids, and that regulate State 3 respiration through the relative contributions of proteins that transport protons, electrons and/or ...
exaly +4 more sources
Ionization constants pKa of cardiolipin. [PDF]
PLoS ONE, 2013 Cardiolipin is a phospholipid found in the inner mitochondrial membrane and in bacteria, and it is associated with many physiological functions. Cardiolipin has a dimeric structure consisting of two phosphatidyl residues connected by a glycerol bridge ...
Gerd Olofsson, Emma Sparr
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Diagnostic Value of Menstrual Blood Lipidomics in Endometriosis: A Pilot Study [PDF]
BiomoleculesEndometriosis is a prevalent chronic inflammatory disease characterized by a considerable delay between initial symptoms and diagnosis through surgery.
Natalia Starodubtseva +8 more
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Research, 2022 Precise metabolic rewiring during heart organogenesis underlies normal cardiac development. Herein, we utilized high-coverage, quantitative lipidomic approaches to construct lipidomic atlases of whole hearts (861 lipids; 31 classes) and mitochondria (587
Huan Miao +9 more
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Cardiolipin drives the catalytic activity of GPX4 on membranes: Insights from the R152H mutant
Redox Biology, 2023 The aim of this study was to examine, in biochemical detail, the functional role of the Arg152 residue in the selenoprotein Glutathione Peroxidase 4 (GPX4), whose mutation to His is involved in Sedaghatian-type Spondylometaphyseal Dysplasia (SSMD).
Antonella Roveri +11 more
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