Results 21 to 30 of about 3,287 (207)
Polyunsaturated fatty acids (PUFA) are particularly susceptible to free radical-induced lipid peroxidation (LPO). Specific deuteration at bis-allylic positions of PUFA (D-PUFA) has been recently proposed as a way to inhibit the LPO.
Rosangela S. Santos +7 more
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Cardiolipin Interactions with Proteins [PDF]
Cardiolipins (CL) represent unique phospholipids of bacteria and eukaryotic mitochondria with four acyl chains and two phosphate groups that have been implicated in numerous functions from energy metabolism to apoptosis. Many proteins are known to interact with CL, and several cocrystal structures of protein-CL complexes exist.
Planas-Iglesias, Joan +5 more
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Structure of Cardiolipin [PDF]
PANGBORN1 considered that the glycerylglycero-phosphate skeleton of cardiolipin contained three phosphoric acid and four glycerol residues (I), the six available hydroxyl groups in this structure being esterified with unsaturated fatty acids in the intact phospholipid.
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Determination of cellular lipids bound to human CD1d molecules. [PDF]
CD1 molecules are glycoproteins that present lipid antigens at the cell surface for immunological recognition by specialized populations of T lymphocytes.
Daryl Cox +7 more
doaj +1 more source
Role of mitochondria and cardiolipins in growth inhibition of breast cancer cells by retinoic acid
Background All-trans-retinoic-acid (ATRA) is a promising agent in the prevention/treatment of breast-cancer. There is growing evidence that reprogramming of cellular lipid metabolism contributes to malignant transformation and progression.
Mineko Terao +15 more
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Background Lipid-protein interactions stabilize protein oligomers, shape their structure, and modulate their function. Whereas in vitro experiments already account for the functional importance of lipids by using natural lipid extracts, in silico methods
Kristyna Pluhackova, Andreas Horner
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2357 Lost and found: Detection of brain cardiolipins in plasma after cardiac arrest
OBJECTIVES/SPECIFIC AIMS: Neurological injury remains as the main limiting factor for overall recovery after cardiac arrest (CA). Currently available indicators of neurological injury are inadequate for early prognostication after return of spontaneous ...
Andrew M. Lamade +9 more
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The interaction of dietary fats and carbohydrates on liver mitochondria were examined in male FBNF1 rats fed 20 different low-fat isocaloric diets.
Irina G. Stavrovskaya +7 more
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A Five-Year Update on Matrix Compounds for MALDI-MS Analysis of Lipids
Matrix-assisted laser desorption and ionization (MALDI) is a widely used soft-ionization technique of modern mass spectrometry (MS). MALDI enables the analysis of nearly all chemical compounds—including polar and apolar (phospho)lipids—with a minimum ...
Jenny Leopold +3 more
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Measuring cardiolipin antibodies [PDF]
EDITOR,—Cardiolipin antibodies have been variously cited as a risk factor for cerebral thrombosis1 2 or splanchnic venous thrombosis,3 or as an epiphenomenon loosely associated with vascular disease.4 Cardiolipin antibodies seem to represent a family of low affinity antibodies which share a limited ability to bind to bovine cardiolipin.
A M, Ward, P A, White
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