Results 31 to 40 of about 4,826 (241)
Modular detergents tailor the purification and structural analysis of membrane proteins including G-protein coupled receptors [PDF]
, 2020 Detergents enable the purification of membrane proteins and are indispensable reagents instructural biology. Even though a large variety of detergents have been developed in the lastcentury, the challenge remains to identify guidelines that allowfine ...
Almeida, F. +12 more
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BMC Biology, 2021 Background Lipid-protein interactions stabilize protein oligomers, shape their structure, and modulate their function. Whereas in vitro experiments already account for the functional importance of lipids by using natural lipid extracts, in silico methods
Kristyna Pluhackova, Andreas Horner
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Mitochondrial ADP/ATP Carrier in Dodecylphosphocholine Binds Cardiolipins with Non-native Affinity. [PDF]
, 2017 Biophysical investigation of membrane proteins generally requires their extraction from native sources using detergents, a step that can lead, possibly irreversibly, to protein denaturation.
Chipot, Christophe +4 more
core +4 more sources
2357 Lost and found: Detection of brain cardiolipins in plasma after cardiac arrest
Journal of Clinical and Translational Science, 2018 OBJECTIVES/SPECIFIC AIMS: Neurological injury remains as the main limiting factor for overall recovery after cardiac arrest (CA). Currently available indicators of neurological injury are inadequate for early prognostication after return of spontaneous ...
Andrew M. Lamade +9 more
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LPS remodeling triggers formation of outer membrane vesicles in Salmonella. [PDF]
, 2016 Outer membrane vesicles (OMV) are proposed to mediate multiple functions during pathogenesis and symbiosis. However, the mechanisms responsible for OMV formation remain poorly understood.
Bording-Jorgenson, Michael +5 more
core +3 more sources
Journal of Lipid Research, 2013 The interaction of dietary fats and carbohydrates on liver mitochondria were examined in male FBNF1 rats fed 20 different low-fat isocaloric diets.
Irina G. Stavrovskaya +7 more
doaj +1 more source
A Five-Year Update on Matrix Compounds for MALDI-MS Analysis of Lipids
Biomolecules, 2023 Matrix-assisted laser desorption and ionization (MALDI) is a widely used soft-ionization technique of modern mass spectrometry (MS). MALDI enables the analysis of nearly all chemical compounds—including polar and apolar (phospho)lipids—with a minimum ...
Jenny Leopold +3 more
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Structure of Cardiolipin [PDF]
Nature, 1958 PANGBORN1 considered that the glycerylglycero-phosphate skeleton of cardiolipin contained three phosphoric acid and four glycerol residues (I), the six available hydroxyl groups in this structure being esterified with unsaturated fatty acids in the intact phospholipid.
openaire +2 more sources
Cardiolipin Interactions with Proteins [PDF]
Biophysical Journal, 2015 Cardiolipins (CL) represent unique phospholipids of bacteria and eukaryotic mitochondria with four acyl chains and two phosphate groups that have been implicated in numerous functions from energy metabolism to apoptosis. Many proteins are known to interact with CL, and several cocrystal structures of protein-CL complexes exist.
Planas-Iglesias, Joan +5 more
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Osmotic shock stimulates de novo synthesis of two cardiolipins in an extreme halophilic archaeon
Journal of Lipid Research, 2004 The present report illustrates the response to osmotic stress of an extreme halophilic archaeon, Halorubrum sp., isolated from the saltern ponds of Margherita di Savoia in southern Italy.
Patrizia Lopalco +3 more
doaj +1 more source