StaR-related lipid transfer-like domain-containing protein CLDP43 affects cardiolipin synthesis and mitochondrial function in Trypanosoma brucei. [PDF]
PLoS ONE, 2022 Cardiolipin is known to interact with bacterial and mitochondrial proteins and protein complexes. Unlike in Escherichia coli and Saccharomyces cerevisiae, the synthesis of cardiolipin is essential for growth of Trypanosoma brucei parasites in culture ...
Alessio Loffreda +2 more
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Ionization constants pKa of cardiolipin. [PDF]
PLoS ONE, 2013 Cardiolipin is a phospholipid found in the inner mitochondrial membrane and in bacteria, and it is associated with many physiological functions. Cardiolipin has a dimeric structure consisting of two phosphatidyl residues connected by a glycerol bridge ...
Gerd Olofsson, Emma Sparr
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Cross-species complementation of bacterial- and eukaryotic-type cardiolipin synthases [PDF]
Microbial Cell, 2017 The glycerophospholipid cardiolipin is a unique constituent of bacterial and mitochondrial membranes. It is involved in forming and stabilizing high molecular mass membrane protein complexes and in maintaining membrane architecture.
Petra Gottier +4 more
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Assessing phospholipase A2 activity toward cardiolipin by mass spectrometry. [PDF]
PLoS ONE, 2013 Cardiolipin, a major component of mitochondria, is critical for mitochondrial functioning including the regulation of cytochrome c release during apoptosis and proper electron transport.
Yuan-Hao Hsu +3 more
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Cardiolipin Alterations during Obesity: Exploring Therapeutic Opportunities
Biology, 2022 Cardiolipin is a specific phospholipid of the mitochondrial inner membrane that participates in many aspects of its organization and function, hence promoting proper mitochondrial ATP production.
Alexandre Prola, Fanny Pilot-Storck
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Structural insights into cardiolipin replacement by phosphatidylglycerol in a cardiolipin-lacking yeast respiratory supercomplex [PDF]
Nature Communications, 2023 Cardiolipin is a hallmark phospholipid of mitochondrial membranes. Despite established significance of cardiolipin in supporting respiratory supercomplex organization, a mechanistic understanding of this lipid-protein interaction is still lacking.
Corey F. Hryc +9 more
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Phase Behavior Of Cardiolipin [PDF]
, 2012 Cardiolipin is a phospholipid with negatively charged headgroups. This lipid is structurally unique in its quadruple-chained configuration and functionally unique in its nearly exclusive involvement in the cellular energy production processes.
Chen, Yi-fan
core +6 more sources
Redox Biology, 2023 Cardiolipin is a unique phospholipid of the inner mitochondrial membrane (IMM) as well as in bacteria. It performs several vital functions such as resisting osmotic rupture and stabilizing the supramolecular structure of large membrane proteins, like ATP
Sehwan Jang, Sabzali Javadov
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Cell cycle arrest and cell survival induce reverse trends of cardiolipin remodeling. [PDF]
PLoS ONE, 2014 Cell survival from the arrested state can be a cause of the cancer recurrence. Transition from the arrest state to the growth state is highly regulated by mitochondrial activity, which is related to the lipid compositions of the mitochondrial membrane ...
Yu-Jen Chao +4 more
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Ischemia In Vivo Induces Cardiolipin Oxidation in Rat Kidney Mitochondria
Biology, 2022 Cardiolipin is a mitochondrial phospholipid that plays a significant role in mitochondrial bioenergetics. Cardiolipin is oxidized under conditions like oxidative stress that occurs during ischemia/reperfusion; however, it is known that even during ...
Arvydas Strazdauskas +5 more
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