Results 11 to 20 of about 5,312 (162)

Structure of Cardiolipin [PDF]

open access: yesNature, 1958
PANGBORN1 considered that the glycerylglycero-phosphate skeleton of cardiolipin contained three phosphoric acid and four glycerol residues (I), the six available hydroxyl groups in this structure being esterified with unsaturated fatty acids in the intact phospholipid.
openaire   +2 more sources

Measuring cardiolipin antibodies [PDF]

open access: yesBMJ, 1995
EDITOR,—Cardiolipin antibodies have been variously cited as a risk factor for cerebral thrombosis1 2 or splanchnic venous thrombosis,3 or as an epiphenomenon loosely associated with vascular disease.4 Cardiolipin antibodies seem to represent a family of low affinity antibodies which share a limited ability to bind to bovine cardiolipin.
A M, Ward, P A, White
openaire   +2 more sources

Clarifying the Roles of Cardiolipin [PDF]

open access: yesBiophysical Journal, 2014
Cardiolipins (CL) are uniquely structured double lipids that are universally found in membranes which couple electron transport and phosphorylation. The proposed roles of CL in these membranes include mainly two aspects: the effects on the structure and dynamics of the membranes' lipid component and the interplay with membrane-associated proteins.
Pöyry, Sanja   +7 more
openaire   +1 more source

An essential bacterial-type cardiolipin synthase mediates cardiolipin formation in a eukaryote

open access: yes, 2012
Cardiolipin is important for bacterial and mitochondrial stability and function. The final step in cardiolipin biosynthesis is catalyzed by cardiolipin synthase and differs mechanistically between prokaryotes and eukaryotes.
Bütikofer, Peter, Serricchio, Mauro
core   +1 more source

Structural insights into cardiolipin replacement by phosphatidylglycerol in a cardiolipin-lacking yeast respiratory supercomplex

open access: yes, 2023
Cardiolipin is a hallmark phospholipid of mitochondrial membranes. Despite established significance of cardiolipin in supporting respiratory supercomplex organization, a mechanistic understanding of this lipid-protein interaction is still lacking.
Venkata K. P. S. Mallampalli   +19 more
core   +1 more source

Cardiolipin synthesizing enzymes form a complex that interacts with cardiolipin-dependent membrane organizing proteins.

open access: yes, 2018
The mitochondrial glycerophospholipid cardiolipin plays important roles in mitochondrial biology. Most notably, cardiolipin directly binds to mitochondrial proteins and helps assemble and stabilize mitochondrial multi-protein complexes.
Vissa, Adriano   +9 more
core   +1 more source

Cardiolipin remodeling: a regulatory hub for modulating cardiolipin metabolism and function [PDF]

open access: yesJournal of Bioenergetics and Biomembranes, 2014
Cardiolipin (CL), the signature phospholipid of mitochondria, is involved in a plethora of cellular processes and is crucial for mitochondrial function and architecture. The de novo synthesis of CL in the mitochondria is followed by a unique remodeling process, in which CL undergoes cycles of deacylation and reacylation. Specific fatty acyl composition
Cunqi, Ye   +2 more
openaire   +2 more sources

Patch clamp characterization of the effect of cardiolipin on MscS of E-coli

open access: yes, 2015
The bacterial mechanosensitive channels MscS and MscL are gated by an increase in membrane tension when the bacterium experiences hypoosmotic shock. It has been well established that membrane lipids modulate the mechanosensitivity and gating behavior of ...
Nakayama, Yoshitaka   +4 more
core   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin   +14 more
wiley   +1 more source

Cardiolipin and Lyso-cardiolipin Analysis by LC/MS.

open access: yes, 2013
A. The dominant cardiolipin (18∶1) peak in mass spectrometry was observed as a doubly charged ion in the negative ion mode. B. Cardiolipin was hydrolyzed by iPLA2 in a mixed-micelle assay and the cardiolipin was extracted by the Bligh/Dyer method and ...
Darren S. Dumlao (393530)   +3 more
core   +1 more source

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