Results 51 to 60 of about 12,138 (223)

PATHOGENIC SERUM IGG ANTICARDIOLIPIN ANTIBODIES AND THE IDIOTYPIC NETWORK

, 1993
OBJECTIVES: To determine whether active immunisation of mice with pathogenic anticardiolipin antibodies (IgG and IgM), derived from the serum of a patient with the antiphospholipid syndrome, could dysregulate the idiotypic cascade and induce the ...
Y. Shoenfeld, R. Bakimer, J. Cohen, M. Blank, VALESINI, Guido   +4 more
core   +1 more source

Clinical Utility of Stillbirth Investigations in Australia: A Cohort Study

Australian and New Zealand Journal of Obstetrics and Gynaecology, Volume 66, Issue 3, June 2026.
ABSTRACT Background Stillbirths impact over two million parents globally every year. Despite current knowledge, technology, and investigations, many stillbirths remain unexplained and are not fully investigated. An important step forward in addressing this gap is determining which investigations produce the highest utility in identifying the cause of ...
Tania Marsden, Mu Cheng, T. Yee Khong, Jane E. Dahlstrom, David Ellwood, Ali Moghimi, Stacey Prystupa, Cecilia Obrien, Fathima S. Cassim, Skye Martin, Michael Coory, Frances M. Boyle, Heidi Shukralla, Alison L. Kent, Ashwati Krishnan Varikara, Patricia Hannaford, Joanne Frost, Joanna Perry‐Keene, Gretchen Pomare, Yin Ping Wong, Geok Chin Tan, Vicki Flenady, Jessica Sexton   +22 more
wiley   +1 more source

Estimation of Antiphospholipid Antibodies, Anticardiolipin Antibodies, Beta-2 Glycoprotein 1 Antibodies in Recurrent Pregnancy Loss - A Case-control Study [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Recurrent miscarriage is the occurrence of three or more consecutive pregnancy loss before 20 weeks of gestation. Antiphospholipid Antibodies (APAs) are one of the causes responsible for recurrent pregnancy loss.
Nilam Bhasker, Meenakshi Kar, Dharmendra Kumar   +2 more
doaj   +1 more source

IgG anti-apolipoprotein A-1 antibodies in patients with systemic lupus erythematosus are associated with disease activity and corticosteroid therapy: an observational study. [PDF]

, 2015
IgG anti-apolipoprotein A-1 (IgG anti-apoA-1) antibodies are present in patients with systemic lupus erythematosus (SLE) and may link inflammatory disease activity and the increased risk of developing atherosclerosis and cardiovascular disease (CVD) in ...
Davari, M, Yiannis Ioannou, Isenberg, D, Paul Bassett, Rahman, A, David Isenberg, Anisur Rahman, Maria Davari, Alber, KF, Ioannou, Y, Oliver Leach, Giles, I, Bassett, P, Karim Alber, Ian Giles, Leach, O, Sara Croca, Chambers, S, Croca, S, Sharon Chambers   +19 more
core   +1 more source

Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci, Feliciana Real‐Fernandez, Federico Pratesi, Francesca Nuti, Paolo Rovero, Anna Maria Papini   +5 more
wiley   +1 more source

Deep capillary retinal ischemia and high-titer prothrombin-associated antiphospholipid antibodies: A case series of three patients

American Journal of Ophthalmology Case Reports, 2019
Purpose: Acute macular neuroretinopathy has been shown to be due to ischemia of the deep capillary retinal plexus and most cases occur in young women; we hypothesized that there may be an association with antiphospholipid antibodies.
Jill R. Schofield, Alan G. Palestine, Victoria Pelak, Marc T. Mathias   +3 more
doaj   +1 more source

Endometrial Epithelial Lactate Deficiency Drives CD8+ T‐Cells Dysregulation in Unexplained Recurrent Implantation Failure

Advanced Science, Volume 13, Issue 26, 8 May 2026.
Unexplained recurrent implantation failure (RIF) represents a significant clinical challenge. Our results demonstrate that reduced lactate production in the RIF endometrium impairs the suppression of cytotoxic CD8+ T‑cells, allowing their proliferation and thereby disrupting the local immune balance essential for successful embryo implantation.
Yuanlin He, Kang Ke, Qingxia Meng, Yichun Guan, Jichun Tan, Hong Lv, Boxian Huang, Chan Tian, Qinyan Zou, Mingxing An, Yao Gao, Jingjing Chen, Xiaoyu Wei, Xi Wang, Hongxia Ma, Yuan Lin, Feiyang Diao, Yayun Gu, Zhibin Hu   +18 more
wiley   +1 more source

Diagnosis of antiphospholipid syndrome in routine clinical practice.

, 2013
The updated international consensus criteria for definite antiphospholipid syndrome (APS) are useful for scientific clinical studies. However, there remains a need for diagnostic criteria for routine clinical use.
Hills, J, Cohen, H, Gardiner, C, Machin, SJ   +3 more
core  

anticardiolipin antibodies and pneumocystis carinii pneumonia

, 1989
On the basis of an increased incidence of anticardiolipin antibodies in patients with infectious mononucleosis which has induce to postulate the existence of cross-reactions between infectious (viral) antigens and cardiolipin, the AUthors report here ...
CONTINI, Carlo, VULLO, Vincenzo, CONTINI C., MASALA, Cesare, MISASI R, LENTI, Luisa, DIPRIMA MA, VULLO V., MASALA C, DI PRIMA, Maria Anna, MISASI, Roberta, SORICE, Maurizio, LENTI L, SORICE M   +13 more
core   +1 more source

Molecular Stratification of Antiphospholipid Syndrome Through Integrative Analysis of the Whole‐Blood RNA Transcriptome

Arthritis &Rheumatology, Volume 78, Issue 5, Page 1124-1133, May 2026.
Objective Antiphospholipid syndrome (APS) is a thromboinflammatory disorder characterized by clinical and mechanistic heterogeneity that complicates early diagnosis and hinders targeted treatment. We aimed to identify distinct molecular endotypes among antiphospholipid antibody (aPL)–positive patients using whole‐blood transcriptomics.
Amala Ambati, Feiyang Ma, Katarina Kmetova, Sherwin Navaz, Claire K. Hoy, Cyrus Sarosh, Ajay Tambralli, Erika Navarro‐Mendoza, Johann E. Gudjonsson, J. Michelle Kahlenberg, Jacqueline A. Madison, Alí Duarte‐García, Jason S. Knight, Yu Zuo   +13 more
wiley   +1 more source