The Past, Present, and Future in Antinuclear Antibodies (ANA)
Autoantibodies are a hallmark of autoimmunity and, specifically, antinuclear antibodies (ANAs) are the most relevant autoantibodies present in systemic autoimmune rheumatic diseases (SARDs).
Juan Irure-Ventura, Marcos López-Hoyos
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Agreement of three commercial anti-extractable nuclear antigen tests: EUROASSAY Anti-ENA Profile, Polycheck Autoimmune Test and FID Connective Profile [PDF]
BackgroundDetection of antibodies to extractable nuclear antigens (ENAs) is needed for the diagnosis in systemic autoimmune diseases. In this study, we compared three reagents using line immunoblot assay (LIA) or multiplex bead immunoassay for detecting ...
Namhee Kim +4 more
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A sore red eye with systemic involvement [PDF]
The study of happiness has long been a playground for philosophical speculation. By lack of empirical measures of happiness, it was not possible to check propositions about the matter.
Lightman, SL +3 more
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Cirrosis biliar primaria: patología subdiagnosticada. Reporte de caso
Introduction: Primary biliary cirrhosis is a chronic, cholestatic, autoimmune, and progressive liver disease that pre-dominantly affects women.
Delmy Saraí Castillo Álvarez +2 more
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Nuclear matrix protein 2 antibody-positive adult dermatomyositis: a case report and review of the literature [PDF]
Dermatomyositis is a clinically heterogenous inflammatory myopathy with unique cutaneous features. Myositis-specific antibodies can aid in diagnosis and anticipation of patient prognosis.
Cartron, Alexander M +3 more
core
Serum antibodies in first-degree relatives of patients with IBD: A marker of disease susceptibility? A follow-up pilot-study after 7 years [PDF]
Introduction: Various disease-specific serum antibodies were described in patients with inflammatory bowel disease and their yet healthy first-degree relatives.
H.P. Török +29 more
core +4 more sources
Late onset systemic sclerosis with seronegativity: a rare presentation of an uncommon disease
Systemic sclerosis (SSc) is an uncommon connective tissue disorder characterized by multisystem involvement with fibrosis of skin and internal organs. Antibody formation is one of the hallmarks of SSc.
D. Saxena +5 more
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Retroperitoneal fibrosis: a case of a patient (63y/o) treated with low-dose methotrexate (MTX) and 6-methylprednisolone (6-MP) [PDF]
Retroperitoneal fibrosis (RPF), is a rare fibroinflammatory disease. The pathogenesis of RPF is still unclear and numerous theories have been reported such as environmental factors, immunologic process, genetic component, local inflammation and advanced
A. Santoro +6 more
core
Recreational exposure during algal bloom in carrasco beach, uruguay: A liver failure case report [PDF]
In January 2015, a 20-month-old child and her family took part in recreational activities at Carrasco and Malvín beaches (Montevideo, Uruguay). An intense harmful algae bloom (HAB) was developing along the coast at that time.
Andrinolo, Dario +8 more
core +3 more sources
1222 patients with suspicion of different autoimmune connective tissue diseases are investigated. Antinuclear antibodies by indirect immunofluorescence reaction, by methods of ELISA and immunoblotting were determined.
I. A. Pashnina +3 more
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