Primary biliary cholangitis (PBC) is a chronic autoimmune liver disease characterized by the presence of antimitochondrial and antinuclear antibodies in patients’ serum.
Alicja Bauer +2 more
doaj +1 more source
Antimitochindrial and antinuclear antibodies in primary biliary cholangitis [PDF]
In this work we reviewed the key antimitochondrial and antinuclear antibodies in primary biliary cholangitis – an autoimmune cholestatic disorder with destruction of intralobular biliary ductules.
Dana Saipiyeva +6 more
doaj +1 more source
Background: Autoimmune connective tissue diseases (AICTD) present with a myriad of clinical manifestations, including cutaneous. These disorders occur because of immune dysregulation that produces autoantibodies targeting connective tissue and internal ...
Rupa D Kondeti +5 more
doaj +1 more source
Complement Activation in Patients With Probable Systemic Lupus Erythematosus and Ability to Predict Progression to American College of Rheumatology-Classified Systemic Lupus Erythematosus. [PDF]
ObjectiveTo evaluate the frequency of cell-bound complement activation products (CB-CAPs) as a marker of complement activation in patients with suspected systemic lupus erythematosus (SLE) and the usefulness of this biomarker as a predictor of the ...
Alexander, Roberta Vezza +12 more
core +2 more sources
Can Antinuclear Antibodies (ANA) be Monoclonal?
Background. Nuclear staining by immunofluorescence in a kidney biopsy is often seen in patients with positive antinuclear antibodies (ANA) in the serum. These ANA are usually polyclonal, but herein we report 9 cases with an unusual finding of monoclonal ...
Laura Biederman +7 more
doaj +1 more source
Antimelanocyte antibodies: A possible role in patients with vitiligo
Background: Vitiligo is an acquired depigmenting skin disorder with multifactorial pathogenesis including genetic, autoimmune, and neuronal factors. Both humoral- and cell-mediated immunities are supposed to have a role in the pathogenesis of vitiligo ...
Maha A El-Gayyar +4 more
doaj +1 more source
Do we need broad immunological work-up in all patients with CIS? [PDF]
BACKGROUND: The aim of this study was to determine the prevalence of altered immunological tests and their clinical significance in patients with clinically isolated syndrome (CIS) suggestive of multiple sclerosis (MS). ----- PATIENTS AND METHODS:
Adamec, Ivan +6 more
core +1 more source
Belimumab : a technological advance for systemic lupus erythematosus patients? Report of a systematic review and meta-analysis [PDF]
Objectives: To undertake a systematic review and meta-analysis to investigate clinical effectiveness of belimumab for patients with systemic lupus erythematosus (SLE) and antinuclear and/or anti-double-stranded DNA (dsDNA) autoantibodies.
Clarke, Aileen +9 more
core +1 more source
Assessment of Serum Prolactin Level in Patients Women with Rheumatoid Arthritis
The prolactin hormone played role in the many autoimmune disorders. To determine the importance of high levels of prolactin in triggering rheumatoid arthritis, thirty patient's women with hyperprolactinemia aged (20-45) years old have been investigated ...
Baghdad Science Journal
doaj +1 more source
Frequency of antinuclear antibodies and rheumatoid factor in healthy Turkish children
The frequency of antinuclear antibodies (ANA) and rheumatoid factor (RF) was investigated in 118 apparently healthy children (56 male, 62 female). The mean age was 9.8 ± 2.3 years.
Özgür Kasapçopur +5 more
doaj +1 more source

