Intracellular and circulating neuronal antinuclear antibodies in human epilepsy
Neurobiology of Disease, 2013 There are overwhelming data supporting the inflammatory origin of some epilepsies (e.g., Rasmussen's encephalitis and limbic encephalitis). Inflammatory epilepsies with an autoimmune component are characterized by autoantibodies against membrane-bound ...
Philip H. Iffland, II +8 more
doaj +1 more source
Immunology markers that can be predictive for the diagnosis of juvenile idiopathic arthritis
Journal of Laboratory Medicine, 2020 This study aimed to investigate the implications of antinuclear antibodies (ANAs) in juvenile idiopathic arthritis (JIA), the association with uveitis and the favorable evolution of the disease.
Sur Lucia M. +9 more
doaj +1 more source
Catastrophic Antiphospholipid Syndrome after Orthotopic Liver Transplant
Case Reports in Transplantation, 2022 Background. Catastrophic antiphospholipid syndrome (CAPS) is an autoimmune thrombogenic disorder of small and large vessels caused by autoantibodies against phospholipids and phospholipid-binding proteins.
R. Okeke +8 more
doaj +1 more source
Clinical and serological features of systemic sclerosis in a multicenter African American cohort: Analysis of the genome research in African American scleroderma patients clinical database. [PDF]
, 2017 Racial differences exist in the severity of systemic sclerosis (SSc). To enhance our knowledge about SSc in African Americans, we established a comprehensive clinical database from the largest multicenter cohort of African American SSc patients assembled
Boin, Francesco +28 more
core +1 more source
Evaluation of the primary biliary cholangitis-related serologic profile in a large cohort of Belgian systemic sclerosis patients [PDF]
, 2020 Background: Systemic sclerosis (SSc) and primary biliary cholangitis (PBC) are autoimmune diseases that may occur concomitantly and are both strongly associated with disease-specific autoantibodies.
Bonroy, Carolien +6 more
core +1 more source
Diagnostic Pathology, 2009 It has been more than 50 years since antinuclear antibodies were first discovered and found to be associated with connective tissue diseases. Since then different methods have been described and used for their detection or confirmation.
Minz Ranjana +2 more
doaj +1 more source
BMC Rheumatology, 2023 Background Antinuclear antibodies (ANA) are antibodies present in several autoimmune disorders. However, a large proportion of the general population (20%) also have a positive test; very few of these individuals will develop an autoimmune disease, and ...
Jacy T. Zanussi +8 more
doaj +1 more source
The importance of detecting anti-DFS70 in routine clinical practice : comparison of different care settings [PDF]
, 2018 Background: Screening for antinuclear antibodies by indirect immunofluorescence (ANA-IIF) is essential in the diagnostic workup of ANA-associated autoimmune rheumatic diseases (AARDs).
Berth, Mario +7 more
core +2 more sources
Antinuclear antibodies in systemic sclerosis associated with increased risk of malignancy
Przegląd Dermatologiczny, 2018 Patients with systemic sclerosis are at 1.5–5-fold increased risk of developing malignant diseases. It has been shown that some types of antinuclear antibodies associated with systemic sclerosis may have predictive value for development of malignant ...
Anna Stochmal +3 more
doaj +1 more source
CD4 T lymphocyte autophagy is upregulated in the salivary glands of primary Sjögren’s syndrome patients and correlates with focus score and disease activity [PDF]
, 2017 Background: Primary Sjögren’s syndrome (pSS) is a common chronic autoimmune disease characterized by lymphocytic infiltration of exocrine glands and peripheral lymphocyte perturbation.
A Bhattacharya +58 more
core +3 more sources