The characterization of Klebsiella pneumoniae associated with neonatal sepsis in low- and middle-income countries to inform vaccine design. [PDF]
Nonne F+17 more
europepmc +1 more source
Transcript Identification Using Arrayed Hydrogels With TrapFISH
TrapFISH is a novel method for high‐throughput single‐cell transcriptomics. It embeds cells in hyaluronic acid hydrogel beads and uses probe hybridization to quantify custom gene panels. By arraying hydrogels in microfluidic devices, cell barcoding is removed, enhancing scalability for studying cellular heterogeneity and rare cell states by targeting ...
David B. Morse+5 more
wiley +1 more source
Pathogenicity and Virulence of Coxiella burnetii: Focus on Q fever. [PDF]
Mezouar S+5 more
europepmc +1 more source
Digital Bioassays on the Slipchip Microfluidic Devices
This review summarizes recent advances in SlipChip‐based digital bioassays, highlighting their simple “load and slip” operation for fluid partitioning which eliminate the need for sophisticated fluidic systems. Applications include digital nucleic acid analysis, digital protein analysis and single‐cell analysis, demonstrating the platform‘s potential ...
Qingqing Luo+5 more
wiley +1 more source
Discovery of glycerol phosphate and an immunogenic glycan motif in rhamnose-rich polysaccharides of Streptococcus uberis. [PDF]
Shi Y+8 more
europepmc +1 more source
Tau protein plays a critical role in the pathology of Alzheimer's disease, utilizing extracellular vesicles (EVs) as a mechanism for intercellular transmission. This study develops a highly sensitive sandwich assay biosensor for detecting and quantifying tau‐associated EVs using surface‐enhanced Raman spectroscopy (SERS).
Saqer Al Abdullah+6 more
wiley +1 more source
Evaluation of the potential for diagnosis of fungal keratitis using a Fusarium-specific antibody. [PDF]
Jo HJ+5 more
europepmc +1 more source
Compact Multichannel Plasmonic Device for Rapid and Versatile Inflammatory Biomarker Analysis
A multichannel plasmonic biosensor has been developed for the simultaneous detection of up to four inflammatory biomarkers relevant to sepsis diagnostics. Its performance has been optimized, and analytical validation has been conducted for the detection in diluted serum, highlighting its potential for clinical applications.
Juliana Fátima Giarola+3 more
wiley +1 more source
Advantages of using complement components in preventive and therapeutic vaccine strategies for infectious and non-infectious diseases. [PDF]
Firdaus NHW+3 more
europepmc +1 more source
Colorimetric Sensors with Enhanced Sensitivity and Angle‐independence
This review discusses various approaches, including the use of photonic crystals and colloidal photonic crystals as structural materials, and surface plasmon resonance as a light manipulation mechanism, to improve the sensitivity of colorimetric sensors.
Hiu Ning Tiffany Chui, Shu Yang
wiley +1 more source